The HDAC1 Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to HDAC1, and Histone Deacetylase 1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The HDAC1 Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, Precipitation, ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, Immunoprecipitation, and Western Blot.
Description
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis