Phospho-Histone H2AX-S139 Rabbit mAb AP0687 from ABclonal Technology

Product Specs
ItemPhospho-Histone H2AX-S139 Rabbit mAb
CompanyABclonal Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAP0687
Antibody TypePrimary Antibody
ClonalityMonoclonal
ReactivityHuman, Mouse, Rat
FormatStore at -20℃. Avoid freeze / thaw cycles.:Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3
ApplicationsWB, IHC, IF
IsotypeIgG
ImmunogenA synthesized peptide derived from human Phospho-Histone H2A.X (S139)
Research AreaDNA Damage & Repair,Epigenetic Modifications,Epigenetic Modifications_Acetylation,Epigenetic Modifications_Phosphorylation,Epigenetics & Nuclear Signaling,Histones,Protein phosphorylation
ModificationsPhospho S139
TargetHistone H2A
Conjugate/TagUnconjugated
HostRabbit
Quantity100 µL
PurityAffinity purification
NCBI Full Gene NameH2A.X variant histone
NCBI Gene AliasesH2AFX, H2A/X, H2A.X
Clone8H6G3
Concentration0.33 mg/ml

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ABclonal Technology

500W Cummings Park, Ste. 6500

Woburn, MA 01801

United States

Phone: 888.754.5670
Int’l: +1857.259.4898

Email: service@abclonal.com

Company Profile

Website: https://abclonal.com/

(1) hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinomaMol CancerDecember 4, 2023Lei Xu, Xiao Ma, Xiuzhong Zhang, Chong Zhang, Yi Zhang, Shuai Gong, Nai Wu, Peng Zhang, Xinyu Feng, Jiaxuan Guo, et al.(BF03008, Biodragon, China), HRP-goat anti-mouse IgG (H + L) (BF03001, Biodragon, China), anti-γ-H2AX (AP0687, Abclonal, China), CoraLite594-conjugated Goat Anti-Rabbit IgG (H + L) (SA00013-4, Proteintech, USA),

(2) Fbxo22 inhibits metastasis in triple-negative breast cancer through ubiquitin modification of KDM5A and regulation of H3K4me3 demethylationCell biology and toxicologyAugust 1, 2023Li S, He J, Liao X, He Y, Chen R, Chen J, Hu S, Sun J.with 10% goat serum for 40 min and incubated with the primary antibodies of rabbit anti-γH2AX (1:50, AP0687, ABclonal, Boston, MA) overnight at 4 °C. Subsequently, cells were then incubated with fluorescent secondary

(3) Ipatasertib exhibits anti‑tumorigenic effects and enhances sensitivity to paclitaxel in endometrial cancer in vitro and in vivoInternational Journal of OncologyJuly 28, 2023Jillian O'Donnell, Ziyi Zhao, Lindsey Buckingham, Tianran Hao, Hongyan Suo, Xin Zhang, Yali Fan, Catherine John, Boer Deng, Xiaochang Shen, et al.Technologies, Inc.), p-S6 (1:500; cat. no. 4858; Cell Signaling Technologies, Inc.), p-H2AX (1:100; cat. no. AP0687; ABclonal Biotech Co., Ltd.) and KIF14 (1:150; cat. no. A10275; ABclonal Biotech Co., Ltd.) for 2 h

(4) Increased cellular senescence in doxorubicin-induced murine ovarian injury: effect of senolyticsGeroScienceJanuary 17, 2023Yueyue Gao, Tong Wu, Xianan Tang, Jingyi Wen, Yan Zhang, Jinjin Zhang, Shixuan Wangprimary antibody (p16 #A0262, ABclonal Technology, China; p21 #A11454, ABclonal Technology, China; γH2AX #AP0687, ABclonal Technology, China) overnight at 4 °C. The next day the sections were incubated with secondary

(5) Peroxiredoxin IV plays a critical role in cancer cell growth and radioresistance through the activation of the Akt/GSK3 signaling pathwaysThe Journal of biological chemistryJuly 1, 2022Ding N, Jiang H, Thapa P, Hao Y, Alshahrani A, Allison D, Izumi T, Rangnekar VM, Liu X, Wei Q.three times and incubated with rabbit mAb against Phospho-Histone H2AX (serine 139) (1:100 dilution) (AP0687; ABclonal) for overnight at 4 °C. After incubation, cells were washed with PBS for three times and stained

(6) Atp11b Deletion Affects the Gut Microbiota and Accelerates Brain Aging in MiceBrain SciencesMay 30, 2022Cuiping Liu, Shibo Zhang, Hongwei Shi, Haicong Zhou, Junyi Zhuang, Yiyang Cao, Natalie Ward, Jiao Wangantibody, rabbit anti-p16INK4 (1:100, A5025, ABclonal, Wuhan, China), or rabbit anti-p-Histone H2AX (1:100, AP0687, ABclonal, Wuhan, China). The slides were washed 5 times with PBS (pH 7.4) for 3 min each and then incubated

(7) HSP90 promotes radioresistance of cervical cancer cells via reducing FBXO6-mediated CD147 polyubiquitinationCancer scienceApril 1, 2022Song Q, Wen J, Li W, Xue J, Zhang Y, Liu H, Han J, Ning T, Lu Z.phosphate‐buffered saline (DPBS) for 1 h. Then, the slides were incubated with a primary antibody against γ‐H2AX (AP0687, ABclonal, Wuhan, China) in a 1:200 dilution in the 3% albumin solution overnight at 4°C. Then, the

(8) IQGAP3 in clear cell renal cell carcinoma contributes to drug resistance and genome stabilityPeerJJanuary 1, 2022Li W, Wang Z, Wang H, Zhang J, Wang X, Xing S, Chen S.from Proteintech (10366-1-AP, 1:1000). Human Phospho-H2AX-S139 antibody was obtained from Abclonal (AP0687, 1:1000). Western blotting The collected cells were centrifuged and lysed in RIPA buffer (150 mM NaCl,

(9) RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 bindingCell death & diseaseDecember 17, 2021Feng X, Jiang T, Yang C, Pang S, Ding Z, Hu H, Wang H, Dong L, Yang N.10494-1-AP), and anti-NQO1 (Cat# 11451-1-AP) were purchased from Proteintech Group, Inc. Anti-p-H2AX (Cat# AP0687) was purchased from Abclonal Inc, China. Anti-p-p38 (Cat# 4511) and anti-p38 (Cat# 8690) were purchased

(10) Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liverNature CommunicationsDecember 1, 2021Heng Lin et al.H167, 250x for IHC), Lamin B1 (ABclonal, A1910, lot# 3560261001, 1000x for IHC), and γH2AX (ABclonal, AP0687, lot# 4000000110, 1000x for IHC). For immunofluorescence, AlexaFluor 488, 594, or 647-conjugated secondary

(11) N6-methyladenosine regulates ATM expression and downstream signalingJournal of CancerJanuary 1, 2021Zhang X, Liu P, Zheng X, Wang J, Peng Q, Li Z, Wei L, Liu C, Wu Y, Wen Y, et al.m6A (202003, Synaptic Systems); BRCA1 (20649-1-AP, Proteintech); H2A.X (A11361, ABclonal); γH2A.X (AP0687, ABclonal ); GAPDH(60004-1-Ig, Proteintech); eIF3A (3411T, CST); Flag (F1804, Sigma-Aldrich); anti‐rabbit IgG HRP‐linked

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Phospho-Histone H2AX-S139 Rabbit mAb from ABclonal Technology

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Phospho-Histone H2AX-S139 Rabbit mAb from ABclonal Technology

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