MTA1 (D40D1) XP ® Rabbit mAb 5647S from Cell Signaling Technology

Product Specs
ItemMTA1 (D40D1) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $371.00 Inquire
Catalog Number5647S
Quantity100 µl
ApplicationsW, IHC-P
ReactivityH, M, R, Mk
TargetMTA1
HostRabbit
ClonalityMonoclonal
NCBI Full Gene Namemetastasis associated 1
Research AreaChromatin Regulation / Nuclear Function
IsotypeIgG
CloneD40D1
Molecular Weight78-82

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) The noncanonical function of liver-type phosphofructokinase potentiates the efficacy of HDAC inhibitors in cancerSignal Transduct Target TherOctober 14, 2025Taiyu Shang, Tianyi Jiang, Jiangqi Tan, Haolin Jiang, Mengyou Xu, Yufei Pan, Yunkai Lin, Xiaowen Cui, Chenxi Tian, Huibo Feng, et al.Thermo Fisher Scientific. Antibodies against cleaved caspase-3 (9664), PARP (9532), p-H2A.x (9718), MTA1 (5647), LSD1 (4218), acetylated lysine (9441), HDAC1 (34589), HDAC2 (5113), and HDAC3 (3949) were purchased

(2) Unraveling the cohesin-chromatin interface: identifying protein interactions that modulate chromosome structure and functionEpigenetics ChromatinJune 2, 2025Natalie L. Rittenhouse, Riya Gohil, June E. Arricastres, Jill M. DowenA9851); NuRD subunits CHD4 (Cell Signaling Technology, 12011S) and MTA1 (Cell Signaling Technology, 5647T); MLL subunits RBBP5 (Bethyl, A300109 A) and WDR5 (Cell Signaling Technology, 13105S); NuA4 subunit

(3) ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancerCell reportsDecember 24, 2024DiCiaccio B, Seehawer M, Li Z, Patmanidis A, Bui T, Foidart P, Nishida J, D'Santos CS, Papachristou EK, Papanastasiou M, et al.(Cell Signaling Technology, 2117), anti-PKN2 (Abcam, ab87812), anti-MTA1 (Cell Signaling Technology, 5647), anti-MTA2 (Cell Signaling Technology, 15793), anti-MBD2 (Abcam, ab188474), anti-MBD3 (Cell Signaling Technology

(4) Histone demethylase enzymes KDM5A and KDM5B modulate immune response by suppressing transcription of endogenous retroviral elementsbioRxivSeptember 28, 2024Huadong Chen, Letitia Sarah, Daniela Pucciarelli, Ying Mao, Morgan E. Diolaiti, Danica Galonić Galonić Fujimori, Alan Ashworth(Cell Signaling, no. 5113, 1:1000), anti-MBD3 (Cell Signaling, no. 14540, 1:1000), anti-MTA1 (Cell Signaling, no. 5647, 1:1000), anti-RBAP46 (Cell Signaling, no. 6882, 1:1000), anti-H4 (Cell Signaling, no. 2592, 1:1000),

(5) The feedback loop between MTA1 and MTA3/TRIM21 modulates stemness of breast cancer in response to estrogenCell Death & DiseaseAugust 17, 2024Jingyao Zhang, Yinuo Wang, Jingjing Zhang, Xin Wang, Jiaxiang Liu, Miaomiao Huo, Ting Hu, Tianyu Ma, Die Zhang, Yu Li, et al.for breast cancer. Materials and methods Antibodies and reagents Antibodies were purchased MTA1(5647, 5646), E-Cadherin (3195), α-N-Cadherin (3240), γ-Catenin (2309), N-Cadherin (13116), Vimentin (5741),

(6) HCN2 Channels in the Ventral Hippocampal CA1 Regulate Nociceptive Hypersensitivity in MiceInternational Journal of Molecular SciencesSeptember 7, 2023Yawen Zheng, Shan Shao, Yu Zhang, Shulu Yuan, Yuanwei Xing, Jiaxin Wang, Xuetao Qi, Kun Cui, Jifu Tong, Fengyu Liu, et al.PBS and subsequently incubated with secondary antibodies at room temperature for 60 min: Alexa Fluor 5647-conjugated goat anti-rabbit IgG (1:500, ab150075, Abcam, Cambridge, UK). The brain slices were stained

(7) The stem cell-supporting small molecule UM171 triggers Cul3-KBTBD4-mediated degradation of ELM2 domain-harboring proteinsThe Journal of biological chemistryMay 1, 2023Žemaitis K, Ghosh S, Hansson J, Subramaniam A.Thermo Fisher Scientific). The following antibodies were used. primary antibodies: RCOR1 (LS-B8157), MTA1 (5647T), MTA2 (15793) HDAC1 (34589T), HDAC2 (5113T), LSD1 (2184S), and ZNF217 (82306) from Cell Signaling Technology.

(8) MTA1-TJP1 interaction and its involvement in non-small cell lung cancer metastasisTranslational OncologyNovember 1, 2022Wei Wang, Mingsheng Ma, Li Li, Yunchao Huang, Guangqiang Zhao, Yongchun Zhou, Yantao Yang, Yichen Yang, Biying Wang, Lianhua YeImageJ software (National Institutes of Health, USA). The antibodies used in the study were: MTA1 (CST, #5647, 1:1000), tight junction protein 1(TJP1) (CST, #6487,1:1000), β-Actin (ABclonal, AC026,1:50,000). RNA

(9) MUC1-C integrates type II interferon and chromatin remodeling pathways in immunosuppression of prostate cancerOncoimmunologyJanuary 1, 2022Hagiwara M, Fushimi A, Bhattacharya A, Yamashita N, Morimoto Y, Oya M, Withers HG, Hu Q, Liu T, Liu S, et al.dilution; Sigma, St. Louis, MO, USA), anti-FBXW7 (ab109617, 1:1000; abcam, Cambridge, MA, USA), anti-MTA1 (5647, 1:1000; CST), anti-MBD3 (14540, 1:1000; CST), anti-IDO1 (86630, 1:1000; CST), anti-WARS (GTX110223,

(10) Low NCOR2 levels in multiple myeloma patients drive multidrug resistance via MYC upregulationBlood cancer journalDecember 4, 2021Mori T, Verma R, Nakamoto-Matsubara R, Siu KT, Panaroni C, Fulzele KS, Mukaihara K, Onyewadume C, Maebius A, Kato H, et al.antibody was purchased from Novus Biologicals. c-Myc (#5605; 1:1,000), IKAROS (#9034; 1:1,000), MTA1 (#5647; 1:1,000), MBD3 (#14540; 1:1,000), HDAC1 (#5356; 1:1,000), and HDAC2 (#5113; 1:1,000), antibodies were

(11) MTA1 Expression Can Stratify the Risk of Patients with Multifocal Non-Small Cell Lung Cancers ≤3 cmTherapeutics and Clinical Risk ManagementDecember 3, 2021Wei Wang et al.The blocking solution was removed and 300 µL of primary antibody (MTA1, diluted at 1:50, Catalog No. 5647S, CST) was added and incubated overnight at 4 °C. The primary antibody solution was removed and the sections

(12) Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic nicheCell reportsSeptember 7, 2021He X, Smith SE, Chen S, Li H, Wu D, Meneses-Giles PI, Wang Y, Hembree M, Yi K, Zhao X, et al.Anti-GRP78/BiP (ET-21) antibody produced in rabbit,Sigma,G9043-200UL;RRID:AB_2279879 MTA1 (D40D1) XP® Rabbit mAb 100ul (10 western blots),Cell Signaling Technology,5647S;RRID:AB_10705601 BrdU antibody,VWR,95019-028 CD44,Fisher,MA1-81995;RRID:AB_928369 Biological samples,Biological

(13) FOXP3 Inhibits the Metastasis of Breast Cancer by Downregulating the Expression of MTA1Frontiers in oncologyJanuary 1, 2021Liu C, Han J, Li X, Huang T, Gao Y, Wang B, Zhang K, Wang S, Zhang W, Li W, et al.(10494-1-AP, Proteintech, 1:500 dilution), GAPDH (10494-1-AP, Proteintech, 1:2000 dilution) or MTA1 (#5647, CST, 1:1000 dilution) and a secondary HRP-conjugated IgG antibody. Enhanced chemiluminescence (Thermo Fisher

(14) Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulationThe Journal of experimental medicineMay 4, 2020Zhan X, Guo S, Li Y, Ran H, Huang H, Mi L, Wu J, Wang X, Xiao D, Chen L, et al.Cell Signaling, RRID:AB_10612242), HDAC2 (1:1,000, 5113, Cell Signaling, RRID:AB_10624871), MTA1 (1:1,000, 5647, Cell Signaling, RRID:AB_10705601), and RBBP7 (1:1,000, 6882, Cell Signaling, RRID:AB_10830730). Western blot

(15) PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesisScience advancesApril 1, 2020Hou Y, Liu W, Yi X, Yang Y, Su D, Huang W, Yu H, Teng X, Yang Y, Feng W, et al.1:1000 for WB), and HIF1α (ab1; ChIP; 1:500 for WB) from Abcam; SUZ12 (3737s; 1:1000 for WB); MTA1 (5647/5647s; IP; ChIP; 1:1000 for WB), and cyclin D1 (55506; 1:200 for IHC) from Cell Signaling Technology; EED

(16) MUC1-C Activates the NuRD Complex to Drive Dedifferentiation of Triple-Negative Breast Cancer CellsCancer ResearchNovember 15, 2019Tsuyoshi Hata et al.USA), anti-MYC (#ab32072; Abcam), anti-ERα (#ab108398; Abcam) anti-β-actin (#A5441; Sigma), anti-MTA1 (#5647), anti-MBD3 (#14540), anti-CHD4 (#11912), anti-HDAC1 (#5356), anti-SOX2 (#D6D9), anti-KLF4 (#D1F2),

(17) FOXO1 Confers Maintenance of the Dark Zone Proliferation and Survival Program and Can Be Pharmacologically Targeted in Burkitt LymphomaCancers (Basel)September 25, 2019Franziska Gehringer, Stephanie E Weissinger, Lotteke Jym Swier, Peter Möller, Thomas Wirth, Alexey UshmorovRelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function. J. Immunol. 2015, 195, 5637–5647. [CrossRef] Dan, H.C.; Cooper, M.J.; Cogswell, P.C.; Duncan, J.A.; Ting, J.P.; Baldwin, A.S. Akt-dependent

(18) Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complexNucleic acids researchFebruary 20, 2019Ivanochko D, Halabelian L, Henderson E, Savitsky P, Jain H, Marcon E, Duan S, Hutchinson A, Seitova A, Barsyte-Lovejoy D, et al.using antibodies for GFP (Living Colors JL-8, Clontech), RBBP4 (R&D systems, MAB7416-SP), MTA1 (CST, 5647) and HDAC2 (CST, 5113). Endogenous co-IP experiments were performed on T47D and MCF7 cells using the

(19) Metastasis-associated protein 1 (MTA1) is transferred by exosomes and contributes to the regulation of hypoxia and estrogen signaling in breast cancer cellsCell communication and signaling : CCSFebruary 19, 2019Hannafon BN, Gin AL, Xu YF, Bruns M, Calloway CL, Ding WQ.(AB06723PU-N, OriGene), internal epitope (sc-17773, Santa Cruz Biotechnology), C-terminal epitope (5647, Cell Signaling Technology), GAPDH (20035, ProMab Biotechnologies, Richmond, CA), RFP (600–401-379,

(20) Refinement of the subunit interaction network within the nucleosome remodelling and deacetylase (Nu RD ) complexThe FEBS JournalDecember 1, 2017Mario Torrado et al.Technology, Danvers, MA, USA: anti-FLAG-HRP (2044S, 1:2,000), anti-HA-HRP (2999S, 1:10,000), anti-MTA1 (5647S, 1:1,000), anti-HDAC1 (5356S, 1:1,000), anti-RBBP4/7 (9067S, 1:1,000); from Santa Cruz Biotechnology:

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MTA1 (D40D1) XP ® Rabbit mAb

MTA1 (D40D1) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (30)

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MTA1 (D40D1) XP ® Rabbit mAb from Cell Signaling Technology

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