Phospho-Jak2 (Tyr1007) (D15E2) Rabbit mAb 4406S from Cell Signaling Technology

Product Specs
ItemPhospho-Jak2 (Tyr1007) (D15E2) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number4406S
Quantity100 µl
ApplicationsW
ReactivityH, M
TargetJak2 (Tyr1007) phosphate
IsotypeIgG
ModificationsJak2 (Tyr1007) phosphate
HostRabbit
CloneD15E2
Molecular Weight125
NCBI Gene AliasesJTK10
ClonalityMonoclonal
NCBI Full Gene NameJanus kinase 2
Research AreaImmunology and Inflammation

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Total flavonoids extracted from Penthorum chinense Pursh inhibits oxidative stress and inflammation in liver cancer cells through the JAK2/STAT3 pathwayTranslational Cancer ResearchJanuary 31, 2026Xiaoyan Li, Xiaoqiang Zhang, Junchao Xuewith primary antibodies β-actin (#4967, 45 kDa, 1:1,000, CST, Danvers, MA, USA), phospho- (p-)JAK2 (#4406, 125 kDa, 1:1,000, CST), JAK2 (#3230, 125 kDa, 1:1,000, CST), p-STAT3 (#52075, 86 kDa, 1:1,000, CST),

(2) PLB1 enhances adhesion and invasion of Trichosporon asahii to lung epithelial cells: insights into the mechanisms of Cav1/JAK/STAT3-induced arginine metabolismRespiratory ResearchJanuary 23, 2026He Zhu, Junhong Ao, Xiaoxian Cheng, Xin Yang, Haitao Li, Rongya Yang1:1000, DF7577, Affinity; anti-CCL12: ab9737, Abcam; anti-JAK2: 1:1000, 3230, CST; anti-p-JAK2: 1:1000, 4406, CST; anti-STAT3: 1:1000, 12640, CST; anti-p-STAT3: 1:2000, 9145, CST; anti-GAPDH: 1:10000, ab181602,

(3) RP105 exerts hepatoprotective effects in sepsis by modulating the SOCS2/JAK2/STAT3 signaling pathwayInt J Mol MedOctober 16, 2025Qin Deng, Hong Duo, Qifa Ye, Ruoping Chen, Zhihui Fu, Jiansheng Xiao, Huaqin Pan, Qi Xiao1:500, cat. no. A13487; ABclonal Biotech Co., Ltd.), anti-phosphorylated-JAK2 (p-JAK2; 1:2,000; cat. no. 4406; Cell Signaling Technology, Inc.), anti-STAT3 (1:1,000; cat. no. 30835; Cell Signaling Technology, Inc.),

(4) Targeting JAK2 with a multifunctional nanoinhibitor for long-lasting anti-inflammatory effects and bone repairJ NanobiotechnologyOctober 10, 2025Yang Liu, Duan Wang, Wenqian Zheng, Yuxuan Wang, Peiyu Wang, Yuping Zhao, Xiaofan Liu, Yaru Shi, Yi Wang, Na Zhou, et al.Proteintech), anti-β-actin (66009-1-Ig, 1:5000, Proteintech), anti-JAK2 (3230, 1:1000, CST), anti-p-JAK2 (4406, 1:1000, CST), anti-STAT3 (4904, 1:2000, CST), and anti-p-STAT3 (9145, 1:2000, CST). Membranes were

(5) Single‐Cell Transcriptomics Reveals ITGA2‐Mediated Metabolic Reprogramming and Immune Crosstalk in Pediatric Thyroid CarcinogenesisAdvanced ScienceSeptember 23, 2025Zhi‐jun Zhan, Ning Li, Yan Sun, Lu Chen, Jun‐da Yin, Yun‐han Shan, Jia‐xing Zeng, Zhe‐cheng Li, Hai‐long Tan, Neng Tang, et al.dilution 1:4000), JAK2 (Proteintech, 17670‐1‐AP, dilution 1:600), pJAK2 (Cell Signaling Technology, 4406S, dilution 1:1000), STAT3 (Cell Signaling Technology, 9139S, dilution 1:1000), pSTAT3 (Cell Signaling Technology

(6) The RNA binding protein CARHSP1 facilitates tumor growth, metastasis and immune escape by enhancing IL-17RA mRNA stabilization in prostate cancerCell BiosciMarch 7, 2025YiFan Jiang, Yanan Wang, KaiHua Xue, JianBin Ma, Shan Xu, Ke Wang, Peng Guo(12790), Cyclin D3 (2936), E-cadherin (3195), N-cadherin (13116), Snail (3895), Phospho-Jak2 (Tyr1007) (4406), NF-κB p65 (8242), Phospho-NF-κB p65 (Ser536) (3033), β-actin (3700), and Vinculin (4650) were purchased

(7) ISRIB facilitates post-spinal cord injury recovery through attenuation of neuronal apoptosis and modulation of neuroinflammationJ Orthop TranslatMarch 7, 2025Qingyang Li, Chi Zhang, Enlin Qi, Mingxin Wu, Haijian Sun, Tao Zhang, Yunpeng Jiang, Hao Li, Ruizhi Jiang, Chuang Li, et al.21891-1-AP), Histone-H3 (1:2000, Proteintech, 17168-1-AP), JAK2 (1:1000, CST, 3230), p-JAK2 (1:1000, CST, 4406), STAT3 (1:2000, Proteintech, 10253-2-AP), p-STAT3 (1:2000, CST, 9145) at 4 °C overnight, and then incubated

(8) Puerarin Ameliorates the Ferroptosis in Diabetic Liver Injure Through the JAK2/STAT3 Pathway Inhibition Based on Network Pharmacology and Experimental ValidationDrug Des Devel TherFebruary 1, 2025Xiaoxu Fan, Shuangqiao Liu, Jing Yu, Jian Hua, Yingtong Feng, Zhen Wang, Yiwei Shen, Wei Lan, Jingxia Wangthis study are as follows: anti-JAK2 (3230T, 1:1000), anti-STAT3 (4904S, 1:2000), anti-phospho-JAK2 (4406T, 1:1000), and anti-phospho-STAT3 (9145T, 1:2000) were purchased from Cell Signaling Technology (Danvers,

(9) Ginsenoside Rh2 regulates triple-negative breast cancer proliferation and apoptosis via the IL-6/JAK2/STAT3 pathwayFront PharmacolJanuary 8, 2025Rumeng Ding, Quancheng Kan, Ting Wang, Ran Xiao, Yanan Song, Duolu Li(1:1,000, #30835, CST); p-Stat3 (1:1,000, #94994, CST); Jak2 (1:1,000, #3230, CST); p-Jak2 (1:1,000, #4406, CST); IL-6 (1:1,000, ab259341, abcam); IL-6R (1:1,000, ab271042, abcam); AMPK α1 (1:1,000, ab32047,

(10) Mechanism of Qingdai in Alleviating Acute Lung Injury by Inhibiting the JAK2/STAT3 Signaling PathwayJournal of Inflammation ResearchDecember 21, 2024Lu Qi, Shun Wang, Tao Guo, Zhuocao Qi, Suwan Wu, Dan Gao, Zhiqiang Yan, Bo Tan, Aidong YangChina). For antibody detection, the following antibodies were used: Anti-JAK2 (3230, 1:1000), Anti-p-JAK2 (4406, 1:1000), Anti-STAT3 (12640, 1:1000), Anti-p-STAT3 (9145, 1:2000), and Anti-COX2 (12282, 1:1000), all

(11) Tumor cell–intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenanceJournal of Experimental MedicineOctober 7, 2024Naijun Miao, Dongqing Cao, Jingsi Jin, Guizhi Ma, Haihui Yu, Junwen Qu, Guiping Li, Caixia Gao, Dong Dong, Fan Xia, et al.Proteintech, RRID: AB_2107436), anti-β-actin (23660-1-AP; Proteintech, RRID: AB_2879307), anti-p-JAK2 (4406; Cell Signaling Technology, RRID: AB_10706164), anti-JAK2 (3230; Cell Signaling Technology, RRID: AB_2128522),

(12) Network Pharmacology and Experimental Validation of the Anti-Inflammatory Effect of Tingli Dazao Xiefei Decoction in Acute Lung Injury TreatmentJ Inflamm ResDecember 19, 2023Chengxi Zhang, Xiaoqian Li, Dan Gao, Huahe Zhu, Shun Wang, Bo Tan, Aidong Yangactivator of transcription 3 (STAT3; 12,640), p-STAT3 (9145), Janus kinase 2 (JAK2; 3230), p-JAK2 (4406), β-actin (4970) were obtained from Cell Signaling Technology (Boston, MA, USA). Protease and phosphatase

(13) IL-6/JAK2-dependent G6PD phosphorylation promotes nucleotide synthesis and supports tumor growthMolecular MetabolismDecember 1, 2023Xuemei Qiu, Hongping Ye, Xiaofei Li, Dan Li, Lu Jiang, Rui Liu, Zhe Zhao, Dan Heand methods 2.1 Materials Antibodies recognizing JAK2 (#3230), STAT3 pY705 (#9145), JAK2 pY1007 (#4406), JAK1 (#77692), JAK3 (#8827) STAT3 (#9139), and Tyk2 (#14193) were purchased from Cell Signaling Technology.

(14) "Surface functionalization of extracellular vesicle nanoparticles with antibodies: a first study on the protein corona ""variable"""Nanoscale advancesSeptember 12, 2023Musicò A, Zenatelli R, Romano M, Zendrini A, Alacqua S, Tassoni S, Paolini L, Urbinati C, Rusnati M, Bergese P, et al.Santa Cruz Biotechnology, USA), mouse anti-CD45 (sc-1178, 35-Z6, Santa Cruz Biotechnology, USA), rabbit anti-EGFR (4406, clone 15F8, Cell Signalling Technology Inc.), mouse anti-HBA1 (H00003039-M02, clone 4F9, Abnova, Jhouzih

(15) IL-27 promotes cardiac fibroblast activation and aggravates cardiac remodeling post myocardial infarctionHeliyonJune 18, 2023Xiaoxue Ma, Qingshu Meng, Shiyu Gong, Shanshan Shi, Xiaoting Liang, Fang Lin, Li Gong, Xuan Liu, Yinzhen Li, Mimi Li, et al.(1:1000, A1352, ABclonal, USA), anti-Col III (1:1000, A0817, ABclonal, USA), anti-phosphor-JAK2 (1:1000, #4406, Cell signaling technology, USA), anti-JAK2 (1:1000, #3230, Cell signaling technology, USA) and anti-β-actin

(16) LncRNA KIAA0087 suppresses the progression of osteosarcoma by mediating the SOCS1/JAK2/STAT3 signaling pathwayExperimental & Molecular MedicineApril 3, 2023Haoli Gong, Ye Tao, Sheng Xiao, Xin Li, Ke Fang, Jie Wen, Pan He, Ming Zeng(1:1000, #9585, Cell Signaling Technology), SOCS1 (1:2000, ab62584, Abcam), p-JAK2 (Tyr1007, 1:1000, #4406, Cell Signaling Technology), JAK2 (1:1500, #3230, Cell Signaling Technology), p-STAT3 (Tyr705, 1:1000,

(17) Delamanid suppresses CXCL10 expression via regulation of JAK/STAT1 signaling and correlates with reduced inflammation in tuberculosis patientsFrontiers in ImmunologyNovember 8, 2022Min Qiao, Shanshan Li, Jinfeng Yuan, Weicong Ren, Yuanyuan Shang, Wei Wang, Rongmei Liu, Fuzhen Zhang, Qing Li, Xiao Wu, et al.(D2E12) Rabbit mAb (CST, cat#3230, 1:1000 dilution), phospho-JAK2 (Tyr1007) (D15E2) Rabbit mAb (CST, cat#4406,1:500 dilution), STAT1 (D1K9Y) Rabbit mAb (CST, cat#14994,1:1000 dilution), phospho-STAT1 (Ser727) (Abcam

(18) Promoted CD4(+) T cell-derived IFN-γ/IL-10 by photobiomodulation therapy modulates neurogenesis to ameliorate cognitive deficits in APP/PS1 and 3xTg-AD miceJournal of neuroinflammationOctober 10, 2022Wu X, Shen Q, Chang H, Li J, Xing D.1:1000); anti-β-Actin (Santa Cruz, sc-47778, 1:1000); anti-CD4 (RD, MAB554-SP, 1:1000); anti-p-JAK2 (CST, 4406, 1:1000); anti-p-STAT4 (Absin, abs131066, 1:1000); anti-p-STAT5 (CST, 4322, 1:1000); anti-T-bet (CST,

(19) FTY720 attenuates APAP‑induced liver injury via the JAK2/STAT3 signaling pathwayInternational journal of molecular medicineMay 1, 2022He X, Kang K, Pan D, Sun Y, Chang B.immunofluorescence),Dilution,Product no.,Company F4/80,1:500,70076,"Cell Signaling Technology, Inc." p-JAK2,"1:1,000",4406,"Cell Signaling Technology, Inc." JAK2,"1:1,000",3230,"Cell Signaling Technology, Inc." p-STAT3,"1:1,000",52075,"Cell Signaling Technology

(20) GM-CSF-miRNA-Jak2/Stat3 Signaling Mediates Chemotherapy-Induced Cancer Cell Stemness in Gastric CancerFrontiers in pharmacologyJanuary 1, 2022Xiang X, Ma HZ, Chen YQ, Zhang DZ, Ma SX, Wang HJ, Liu DM, Yuan Y, Cai H.anti-SOCS2 (2779T, Cell Signaling Technology), anti-JAK2 (3230T, Cell Signaling Technology), anti-p-JAK2 (4406T, Cell Signaling Technology), anti-STAT3 (9139T, Cell Signaling Technology), anti-p-STAT3 (9145T, Cell Signaling Technology

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9/14/2016Perfect Phosphor-Jak2 Antibody Franz RicklefsThis is a very good phosphor-JAK2 antibody. Just follow the instructions of the manufacturer. I am interested in multiple pathways inside the cell.

Phospho-Jak2 (Tyr1007) (D15E2) Rabbit mAb

Phospho-Jak2 (Tyr1007) (D15E2) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-Jak2 (Tyr1007) (D15E2) Rabbit mAb from Cell Signaling Technology

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