SMC3 (D47B5) Rabbit mAb 5696S from Cell Signaling Technology

Product Specs
ItemSMC3 (D47B5) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number5696S
Quantity100 µl
ApplicationsW, IP, IF-IC
ReactivityH, M, R, Mk
TargetSMC3
HostRabbit
NCBI Gene AliasesBAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1
ClonalityMonoclonal
NCBI Full Gene Namestructural maintenance of chromosomes 3
Research AreaCell Cycle / Checkpoint Control
IsotypeIgG
CloneD47B5
Molecular Weight140

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Chromatin-mediated anticipatory control of type I interferon production in plasmacytoid dendritic cellsImmunityFebruary 10, 2026Nicholas M. Adams, Aleksandra Galitsyna, Ioanna Tiniakou, Eduardo Esteva, Ai C. Ra, Simon Ullrich, Stephen T. Yeung, Yanjun Tan, Joseph N. Pucella, Igor Dolgalev, et al.(M-20),Santa Cruz Biotechnology,Cat# sc-6217 Rabbit anti-SMC3 mAb (D47B5),Cell Signaling Technology,Cat# 5696; RRID:AB_10705575 AlexaFluor 488 goat anti-rabbit IgG (H+L),Thermo Fisher Scientific,Cat# A-11034;

(2) Lysine deacetylase inhibitors have low selectivity in cells and exhibit predominantly off‐target effectsFEBS Open BioOctober 31, 2024Kiara E. Bornes, Marcus A. Moody, Thomas M. Huckaba, Megan C. Benz, Emily C. McConnell, Maryam Foroozesh, Van H. Barnes, Bridgette M. Collins‐Burow, Matthew E. Burow, Terry J. Watt, et al.Cell Signaling Technologies, Danvers, MA USA, unless otherwise noted) were used in this study: SMC3 (5696), SMC3‐acetyl‐K105/K106 (Sigma Aldrich MABE1073, St. Louis, MO, USA), α‐Tubulin (3873), α‐Tubulin‐acetyl‐K40

(3) The NIPBL-gene mutation of a Cornelia de Lange Syndrome patient causes deficits in the hepatocyte differentiation of induced Pluripotent Stem Cells via altered chromatin-accessibilityCellular and molecular life sciences : CMLSOctober 25, 2024Foglia M, Guarrera L, Kurosaki M, Cassanmagnago GA, Bolis M, Miduri M, Cereseto A, Umbach A, Craparotta I, Fratelli M, et al.anti-NIPBL (Betyl Biotech A301-779A), anti-SMC1A (Cell Signaling #6892), anti-SMC3 (Cell Signaling #5696), anti-RAD21 (Abcam ab992), anti-MAU2 (Abcam ab183033), anti-HistoneH3 (Upstate 06–599) and anti-TOPO

(4) Discovery of a Highly Potent and Selective HDAC8 Degrader: Advancing the Functional Understanding and Therapeutic Potential of HDAC8Journal of Medicinal ChemistryAugust 8, 2024Yufeng Xiao, Nikee Awasthee, Yi Liu, Chengcheng Meng, Michael Y. He, Seth Hale, Rashmi Karki, Zongtao Lin, Megan Mosterio, Benjamin A. Garcia, et al.(H3K27ac, Cell Signaling Technology, 8173, 1:10,000 dilution), anti-SMC3 (Cell Signaling Technology, 5696, 1:2000 dilution), anti-SMC3 acetylated at lysines 105 and 106 (Millipore-Sigma, MABE1073, 1:2000 dilution),

(5) Sulfotransferase SULT2B1 facilitates colon cancer metastasis by promoting SCD1‐mediated lipid metabolismClinical and Translational MedicineFebruary 19, 2024Gang Che, Wankun Wang, Jiawei Wang, Cheng He, Jie Yin, Zhendong Chen, Chao He, Xujing Wang, Yan Yang, Jian Liu(proteintech) GAPDH,60004‐1‐Ig (proteintech) Ki67,27309‐1‐AP (proteintech) SMC1A,21695‐1‐AP (proteintech) SMC3,#5696S (CST) secondary antibodies,"#7074, #7076 (CST)" Fluorescent secondary antibody,"SA00013‐4, SA00014‐10

(6) Endogenous expression of inactive lysine deacetylases reveals deacetylation-dependent cellular mechanismsPLOS ONESeptember 18, 2023Tasha B. Toro, Elena V. Skripnikova, Kiara E. Bornes, Kun Zhang, Terry J. Watt(Santa Cruz Biotechnology sc-28386), KDAC8 (Cell Signaling Technologies 66042), SMC3 (Cell Signaling Technologies 5696), SMC3-acetyl-K105/K106 (Sigma Aldrich MABE1073), β-Tubulin (Developmental Hybridoma Studies Bank E7),

(7) The Sponge-Derived Brominated Compound Aeroplysinin-1 Impairs the Endothelial Inflammatory Response through Inhibition of the NF-κB PathwayMarine drugsSeptember 26, 2022Vidal I, Castilla L, Marrero AD, Bravo-Ruiz I, Bernal M, Manrique I, R Quesada A, Medina MÁ, Martínez-Poveda B.overnight at 4 °C. Phospho-Akt (Ser473) rabbit mAb (#9271), Akt (#9272), SMC3 (D47B5) rabbit mAb (#5696), phospho-IKKα/β (Ser176/180; 16A6) rabbit mAb (#2697), IKKβ (D30C6) rabbit mAb (#8943) and α-Tubulin (DM1A) mouse mAb

(8) cccDNA Surrogate MC-HBV-Based Screen Identifies Cohesin Complex as a Novel HBV Restriction FactorCellular and molecular gastroenterology and hepatologyJanuary 1, 2022Wu Z, Wang L, Wang X, Sun Y, Li H, Zhang Z, Ren C, Zhang X, Li S, Lu J, et al.used for Western blot in this study were as follows: rabbit anti-SMC3 monoclonal antibody (1:2000, 5696; Cell Signaling Technology, Danvers, MA), rabbit anti-SMC1A monoclonal antibody (1:10,000, ab109238;

(9) CTCF Expression and Dynamic Motif Accessibility Modulates Epithelial-Mesenchymal Gene ExpressionCancersJanuary 1, 2022Johnson KS, Hussein S, Chakraborty P, Muruganantham A, Mikhail S, Gonzalez G, Song S, Jolly MK, Toneff MJ, Benton ML, et al.anti-BORIS/CTCFL (PA5-97639, polyclonal rabbit, 1:1000, Thermo Fisher Scientific, Waltham, MA, USA), anti-SMC3 (#5696, monoclonal rabbit, 1:1000, Cell Signaling Technologies, Danvers, MA, USA), anti-YY1 (#46395S, monoclonal

(10) Cohesin mutations are synthetic lethal with stimulation of WNT signalingeLifeDecember 7, 2020Chue Vin Chin, Jisha Antony, Sarada Ketharnathan, Anastasia Labudina, Gregory Gimenez, Kate M Parsons, Jinshu He, Amee J George, Maria Michela Pallotta, Antonio Musio, et al.Supplementary file 1. Antibodies Primary antibodies used are as follows: anti-RAD21 (ab992), anti-SMC3 (#5696, CST), anti-STAG2 (ab4463), anti-γ-Tubulin (T5326; Sigma-Aldrich) in 1:5000, anti-fibrillarin (ab5821),

(11) Regulation of sister chromatid cohesion by nuclear PD-L1Cell researchJuly 1, 2020Yu J, Qin B, Moyer AM, Nowsheen S, Tu X, Dong H, Boughey JC, Goetz MP, Weinshilboum R, Lou Z, et al.(HA) tag. Sororin plasmid was purchased from Origene. Anti-SMC1 antibody (4802S), anti-SMC3 antibody (5696S), anti-SCC1 antibody (4321S), anti-STAG2 antibody (5882S), anti-WAPL antibody (77428S) and anti-PD-L1

(12) Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomicsMolecular oncologyJune 1, 2020Bensimon A, Koch JP, Francica P, Roth SM, Riedo R, Glück AA, Orlando E, Blaukat A, Aebersold DM, Zimmer Y, et al.(#4934), cdc2 (#9116T), cell cycle‐dependent kinase 2 (CDK2; #2546T), H2AX (#7631S), 11 (#8967), SMC3 (#5696), and MET (#8198S and #4560) antibodies were all obtained from Cell Signaling Technology (Danvers, MA,

(13) Interactome of the Autoimmune Risk Protein ANKRD55Frontiers in immunologyJanuary 1, 2019Ugidos N, Mena J, Baquero S, Alloza I, Azkargorta M, Elortza F, Vandenbroeck K.rabbit polyclonal (Cat. No. 21695-1-AP; 1:500) from Proteintech; anti-SMC3 rabbit monoclonal (Cat. No. 5696; 1:2,000), anti-14-3-3 pan (1:1,000) from Cell Signaling Technology; anti-PRKDC mouse monoclonal (Cat.

(14) A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous diseaseNature communicationsOctober 25, 2018Arnadottir GA, Norddahl GL, Gudmundsdottir S, Agustsdottir AB, Sigurdsson S, Jensson BO, Bjarnadottir K, Theodors F, Benonisdottir S, Ivarsdottir EV, et al.

(15) Interactions among oscillatory pathways in NF-kappa B signalingBMC Systems BiologyDecember 1, 2011Yunjiao Wang, Pawel Paszek, Caroline A Horton, Douglas B Kell, Michael RH White, David S Broomhead, Mark R MuldoonMRH: Oscillations in NF-kappa B signaling control the dynamics of gene expression. Science 2004, 306(5696):704-708. 13. Horton CA: Computational Modelling of Cell Signalling Pathway Dynamics. PhD thesis School

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SMC3 (D47B5) Rabbit mAb

SMC3 (D47B5) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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SMC3 (D47B5) Rabbit mAb from Cell Signaling Technology

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