Amyloid Beta (N) Anti-Human Rabbit IgG Affinity Purify 18584 from IBL- America

Product Specs
ItemAmyloid Beta (N) Anti-Human Rabbit IgG Affinity Purify
CompanyIBL- America
Price $596.00Supplier Page View Company Product Page
Catalog Number18584
ApplicationsIHC, WB
HostRabbit
ReactivityHuman
Quantity100 ug
IsotypeIgG
Regulatory StatusFor research use only, not for use in diagnostic procedures
ClonalityPolyclonal
FormatLyophilized product from 1% BSA in PBS containing 0.05% NaN3
PurityAffinity purify
ImmunogenSynthetic peptide for N-terminal of Human Amyloid β
StorageLyophilized product: 5 years at 2 - 8 °C; Solution: 2 years at -20°C

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IBL- America

8201 Central Ave NE Suite P

Minneapolis, Minnesota 55432

United States

Phone: 888-523-1246
763-780-2988

Company Profile

Website: http://www.ibl-america.com/

(1) Molecular signatures of resilience to Alzheimer’s disease in neocortical layer 4 neuronsNature CommunicationsJanuary 31, 2026S. Akila Parvathy Dharshini, Jorge Sanz-Ros, Jie Pan, Weijing Tang, Kristen Vallejo, Yu Chen Liu, Marcos Otero-Garcia, Inma Cobosperoxidase activity. The primary antibodies used included rabbit anti-human amyloid beta (1:500, IBL 18584), rabbit anti-GFAP (1:2000, Dako Z0334), and rabbit anti-Iba1 (1:500, FujiFilm 019-19741). Sections

(2) Transferrin receptor-binding blood-brain barrier shuttle enhances brain delivery and plaque-clearing efficacy of a therapeutic anti-Aβ antibodyFluids and Barriers of the CNSNovember 27, 2025Marta Ramos Vega, Henrik H. Hansen, Camilla Stampe Jensen, Evdoxia Alexiou, Martin R. Madsen, Franziska Wichern, Maiken Søndergaard Kristiansen, Jacob Lercke Skytte, Casper Graversen Salinas, Florence Sotty, et al.#709-655-149, polyclonal, Jackson ImmunoResearch, West Grove, PA) and rabbit anti-human Aβ (1:100; #18584, polyclonal, IBL, Minneapolis, MN) in PBS with 0.2% Triton X-100/3% donkey serum/5% DMSO at 37 °C for

(3) Tau Accumulation Induces Microglial State Alterations in Alzheimer's Disease Model MiceeNeuroNovember 26, 2024Kenichi Nagata, Shoko Hashimoto, Daisuke Joho, Ryo Fujioka, Yukio Matsuba, Misaki Sekiguchi, Naomi Mihira, Daisuke Motooka, Yu-Chen Liu, Daisuke Okuzaki, et al.(R&D Systems, catalog #AF1197, RRID:AB_2234687), rabbit anti-amyloid-β antibody (IBL-America, catalog #18584, RRID:AB_10705431), mouse anti-phosphorylated tau antibody (Fujirebio Europe NV, catalog #90206), mouse

(4) Molecular Signatures of Resilience to Alzheimer’s Disease in Neocortical Layer 4 NeuronsbioRxivNovember 6, 2024S Akila Parvathy Dharshini, Jorge Sanz-Ros, Jie Pan, Weijing Tang, Kristen Vallejo, Marcos Otero-Garcia, Inma Cobosperoxidase activity. The primary antibodies used included rabbit anti-human amyloid beta (1:500, IBL 18584), rabbit anti-GFAP (1:2000, Dako Z0334), and rabbit anti-Iba1 (1:500, FujiFilm 019–19741). Sections

(5) APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer diseaseMolecular therapy : the journal of the American Society of Gene TherapyMay 1, 2024Jackson RJ, Keiser MS, Meltzer JC, Fykstra DP, Dierksmeier SE, Hajizadeh S, Kreuzer J, Morris R, Melloni A, Nakajima T, et al.quantification Every 10th section was stained as described above using rabbit anti-Abeta (1:500, IBL, 18584) for amyloid beta. Amyloid dense core plaques were labeled by 0.05% ThioS (Sigma-Aldrich) in 50% ethanol

(6) Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer’s diseaseScientific ReportsDecember 5, 2022Heng Zhou, Hanyan Li, Niket Gowravaram, Moqin Quan, Naila Kausar, Stephen N. GompertsAxio Imager Z2). Expression of amyloid-β plaque was assessed using amyloid-β primary antibody (IBL 18584, 1:500) and secondary fluorescent antibody (Invitrogen A21207, 1:500). Statistical analysis All group

(7) Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microgliaMolecular neurodegenerationJune 11, 2022Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK, et al.was performed using the following primary antibodies: rabbit anti-human amyloid beta (IBL America, 18584; 1:500), rat anti-CD68 (BioRad, MCA1957A; 1:500), goat anti-Iba1 (Novus, NB100-1028; 1:500), mouse anti-pTau

(8) Hop flower extracts mitigate retinal ganglion cell degeneration in a glaucoma mouse modelScientific ReportsDecember 10, 2020Tomoko Hasegawa, Hanako O. Ikeda, Sachiko Iwai, Norio Sasaoka, Akira Kakizuka, Akitaka Tsujikawa1% bovine serum albumin, sections were incubated overnight with anti-amyloid β antibody (2.5 μg/mL, 18584, Immuno-Biological Laboratories, Fujioka, Gunma, Japan). The sections were then washed with TBST and

(9) Multiple BACE1 inhibitors abnormally increase the BACE1 protein level in neurons by prolonging its half-lifeAlzheimer's & dementia : the journal of the Alzheimer's AssociationSeptember 1, 2019Liu L, Lauro BM, Ding L, Rovere M, Wolfe MS, Selkoe DJ.805901, (rabbit, Biolegend); for hAβ (1–42 specific), 21Fl2, (mouse, homemade); for hAβ (1–43 specific), 18584, (rabbit, IBL, RRID: AB_2341377); and for BACE1 BAF931 (goat, R&D system). For TACE, Cathepsin B and

(10) A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursorThe Journal of cell biologyFebruary 4, 2019Liu L, Ding L, Rovere M, Wolfe MS, Selkoe DJ.specific), HJ-2 (mouse, homemade); for Aβ (1–42 specific), 21Fl2 (mouse, homemade); for Aβ (1–43 specific), 18584 (rabbit, RRID: AB_2341377; IBL). For the commercial ELISA assay, ELISA for APP-CTFβ, 27776 (IBL); for

(11) Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegenerationNature immunologyNovember 1, 2018Ryu JK, Rafalski VA, Meyer-Franke A, Adams RA, Poda SB, Rios Coronado PE, Pedersen LØ, Menon V, Baeten KM, Sikorski SL, et al.(1:1000; J. L. Degen, Cincinnati Children’s Hospital Medical Center), and human Aβ (1:500; IBL-America #18584). Amyloid plaques were labeled with methoxy-XO4 (fluorescent probe for Aβ, Tocris) as described63. Images

(12) Istradefylline reduces memory deficits in aging mice with amyloid pathologyNeurobiology of diseaseFebruary 1, 2018Orr AG, Lo I, Schumacher H, Ho K, Gill M, Guo W, Kim DH, Knox A, Saito T, Saido TC, et al.et al. Page 6 Author Manuscript rabbit anti-human amyloid-β (N) IgG antibody (1:250, IBL-America, 18584), followed by a 1-h incubation at room temperature with goat anti-mouse IgG2a-488, goat anti-mouse IgG1-546

(13) The age-related slow increase in amyloid pathology in APP.V717I mice activates microglia, but does not alter hippocampal neurogenesisNeurobiology of AgingJanuary 1, 2018Lianne Hoeijmakers, Gideon F. Meerhoff, Janneke W. de Vries, Silvie R. Ruigrok, Anne-Marie van Dam, Fred van Leuven, Aniko Korosi, Paul J. Lucassenan antibody directed against the N-terminal of the amyloid peptide (rabbit polyclonal anti-Ab[N], #18584, IBL Japan, Gumma, Japan; Marlatt et al., 2013). IHC for CD68 marked microglial lysosomal activation

(14) Prolonged Running, not Fluoxetine Treatment, Increases Neurogenesis, but does not Alter Neuropathology, in the 3xTg Mouse Model of Alzheimer’s DiseaseNeurogenesis and Neural PlasticityAugust 27, 2015Michael W. Marlatt, Michelle C. Potter, Thomas A. Bayer, Henriette van Praag, Paul J. Lucassenincubation with 88 % FA. The primary Ab was directed against N-terminal Aβ peptides (1:250 IBL Japan #18584). Sections were developed using biotinylated secondary Ab, Goat anti-Rabbit 1:200, and Vector Labs ABC

(15) Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse BrainScience Translational MedicineNovember 20, 2013Eloise Hudry et al.immunostaining for amyloid plaques (rabbit anti-human Aβ antibody, Immuno-Biological Laboratories, 18584). Scale bar, 200 μm. (B) Analysis of the density of amyloid deposits in the cortex (left panel) and

(16) Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brainMolecular NeurodegenerationDecember 1, 2010Maho Kondo et al.2D1 antibodies were generated as described in [26]. Rabbit polyclonal antibodies to human Aβ (IBL #18584) and 4G8 (Signet COVANCE), and the APP cytoplasmic domain (Sigma #8717) were purchased. Brain lysates,

(17) Accumulation of intraneuronal Abeta correlates with ApoE4 genotypeActa neuropathologicaMay 1, 2010Christensen DZ, Schneider-Axmann T, Lucassen PJ, Bayer TA, Wirths O.antibodies used were directed against N-terminal Ab peptides [Ab[N], IBL (rabbit polyclonal, catalog No. 18584), Hamburg, Germany, 1:200] [35], G2-10 (Ab40, The Genetics Company, Switzerland, 1:500), fibrillar Ab

(18) Formic acid is essential for immunohistochemical detection of aggregated intraneuronal Abeta peptides in mouse models of Alzheimer's diseaseBrain researchDecember 8, 2009Christensen DZ, Bayer TA, Wirths O.

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Amyloid Beta (N) Anti-Human Rabbit IgG Affinity Purify from IBL- America

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IBL- America

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Amyloid Beta (N) Anti-Human Rabbit IgG Affinity Purify from IBL- America

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