Mouse TGF¿ß RII Biotinylated Antibody BAF532 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse TGF¿ß RII Biotinylated Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $579.00Supplier Page View Company Product Page
Catalog NumberBAF532
NCBI Gene AliasesRIIDN, TbetaR-II, 1110020H15Rik, TBR-II, TbetaRII, DNIIR
ApplicationsFlow Cytometry,Western Blot
Conjugate/TagBiotin
ReactivityMouse
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
IsotypeIgG
TargetTGF-beta RII
HostGoat
Quantity50 ug
NCBI Full Gene Nametransforming growth factor, beta receptor II
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse TGF¿ß RII and S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TGF¿ß RII, Ile24-Asp184, Accession # Q62312
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Biotin

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) TGF-β and Eomes control the homeostasis of CD8+ regulatory T cellsThe Journal of experimental medicineJanuary 4, 2021Mishra S, Liao W, Liu Y, Yang M, Ma C, Wu H, Zhao M, Zhang X, Qiu Y, Lu Q, et al.purchased from eBioscience, Biolegend, Invitrogen, and Tonbo. TGF-β RII antibody was from R&D Systems (BAF532). Anti-CD16/32 (2.4G2) was produced in the laboratory and used in all FACS staining as FcR blocker.

(2) An immortalized cell line derived from renal erythropoietin-producing (REP) cells demonstrates their potential to transform into myofibroblastsScientific reportsAugust 2, 2019Sato K, Hirano I, Sekine H, Miyauchi K, Nakai T, Kato K, Ito S, Yamamoto M, Suzuki N.with biotin-conjugated CD73 antibody (Thermo Fisher Scientific) or biotin-conjugated TGFβR2 antibody (BAF532; R&D Systems) for 30 minutes on ice and then washed and stained with streptavidin-APC for 30 minutes.

(3) SMAD4 impedes the conversion of NK cells into ILC1-like cells by curtailing non-canonical TGF-β signalingNature immunologySeptember 1, 2017Cortez VS, Ulland TK, Cervantes-Barragan L, Bando JK, Robinette ML, Wang Q, White AJ, Gilfillan S, Cella M, Colonna M.(N6-1233), and human CD103 (Ber-ACT8) were purchased from BD Biosciences. Biotin-conjugated TGFβR2 (Cat # BAF532) and human CD9 (209306) were purchased from R&D Systems. Fluorochrome-conjugated antibodies to mouse

(4) NK1.1+ CD8+ T cells escape TGF-β control and contribute to early microbial pathogen responseNature communicationsOctober 6, 2014Ruiz AL, Soudja SM, Deceneux C, Lauvau G, Marie JC.streptavidine were purchased from BD Biosciences (France) or eBioscience (France). Anti-mouse TGF-βRII (BAF532), was purchased from R&D Systems and anti-human granzyme B (GB11) was purchased from Invitrogen. Intracellular

(5) TGF-β prevents T follicular helper cell accumulation and B cell autoreactivityThe Journal of clinical investigationOctober 1, 2014McCarron MJ, Marie JC.

(6) TGF-β cytokine signaling promotes CD8+ T cell development and low-affinity CD4+ T cell homeostasis by regulation of interleukin-7 receptor α expressionImmunityAugust 22, 2013Ouyang W, Oh SA, Ma Q, Bivona MR, Zhu J, Li MO.

(7) TGF-β type II receptor/MCP-5 axis: at the crossroad between joint and growth plate developmentDevelopmental cellJuly 17, 2012Longobardi L, Li T, Myers TJ, O'Rear L, Ozkan H, Li Y, Contaldo C, Spagnoli A.mesenchyme limb bud cells are subjected to immunoselection using biotinylated TβRII, biotinylated PDGFRB (BAF532 and BAF1042, R&D Systems) and Jagged 1 (sc-6011, Santa Cruz Biothechnolgy) antibodies. Biotinylation

(8) CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potentialJournal of immunology (Baltimore, Md. : 1950)February 15, 2012Radulovic K, Manta C, Rossini V, Holzmann K, Kestler HA, Wegenka UM, Nakayama T, Niess JH.PE-conjugated anti–IL-10R1 1B1.3a (catalog no. 559914). The biotinylated mAbs binding TGF-bRII (catalog no. BAF532) and APC-conjugated anti-LAP (TGF-b1) 27232 (catalog no. FAB2463A) were purchased from R&D Systems.

(9) Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic miceThe Journal of biological chemistryJuly 4, 2003Denton CP, Zheng B, Evans LA, Shi-wen X, Ong VH, Fisher I, Lazaridis K, Abraham DJ, Black CM, de Crombrugghe B.

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Mouse TGF-beta RII Biotinylated Antibody

Mouse TGF¿ß RII Biotinylated Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Mouse TGF¿ß RII Biotinylated Antibody from R&D Systems, a Bio-Techne Brand

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