Human Mer Antibody AF891 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman Mer Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $569.00Supplier Page View Company Product Page
Catalog NumberAF891
Quantity100 ug (also 25 ug)
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization,CyTOF-ready, Cell Culture
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ConcentrationLYOPH
PurityAntigen Affinity-purified
ReactivityHuman,Mouse,Primate
HostGoat
TargetMer
IsotypeIgG
Antibody TypePrimary Antibodies
NCBI Gene Aliasesc-Eyk, RP38, Tyro12, c-mer, MER
NCBI Full Gene NameMER proto-oncogene, tyrosine kinase
ClonalityPolyclonal
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant human Mer, Arg26-Ala499, Accession # Q12866
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
ValidationKnockout Validated

Specifications/Features

Available conjugates: Unconjugated

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Development and validation of a potency assay matrix for optimized and consistent manufacture of clinical mesenchymal stem/stromal cellsFrontiers in ImmunologyFebruary 19, 2026Patrick Niekamp, Dongsheng Gu, Jie Jiang, Erik J. Woods, Brian H. Johnstoneindicated, 2µg/mL M-CSF neutralizing antibody (R&D systems, MAB216-100), 2µg/mL MerTK antibody (R&D Systems, AF891), 50nM CSF1R inhibitor (Selleckchem, S7725) or 2.5µM MerTKi (Selleckchem, S7342) was added. T cell

(2) A single mutation in the PrM gene of Zika virus determines AXL dependency for infection of human neural cellsJournal of virologyApril 15, 2025Khasa R, Ogden SC, Wang Y, Mou Z, Metzler AD, Xie X, Dai X, Tang H.(R&D Systems, Cat # AF1750), goat-anti-Tyro3 (R&D Systems, Cat # AF859), goat-anti- MerTK (R&D Systems, Cat # AF891), normal goat IgG (R&D Systems, Cat # AB-108-C), or mouse-anti-flavivirus envelope (Clone D1-4G2-4-15

(3) Multiple cell types support productive infection and dynamic translocation of infectious Ebola virus to the surface of human skinScience advancesJanuary 3, 2025Messingham KN, Richards PT, Fleck A, Patel RA, Djurkovic M, Elliff J, Connell S, Crowe TP, Munoz Gonzalez J, Gourronc F, et al.(R&D Systems, #AF1750), TIM-4 (R&D Systems, #AF2929), Tyro3 (R&D Systems, #AF859), MerTK (R&D Systems, #AF891), AXL (R&D Systems, #AF154), DC-SIGN (R&D Systems, #MAB1621), and LSECtin (R&D Systems, #AF2947) or

(4) Regulation of Mertk Surface Expression via ADAM17 and γ-Secretase Proteolytic ProcessingInternational journal of molecular sciencesApril 17, 2024Lahey KC, Varsanyi C, Wang Z, Aquib A, Gadiyar V, Rodrigues AA, Pulica R, Desind S, Davra V, Calianese DC, et al.Cell Signaling Technology, Danvers, MA, USA; includes nicastrin, PEN2, Presenilin 1, Presenilin 2)-N-Mertk (AF891, R&D Systems, Minneapolis, MN, USA)-C-Mertk (D21F11, Cell Signaling Technology, Danvers, MA, USA)-B-actin

(5) The Vitamin K-Dependent Anticoagulant Factor, Protein S, Regulates Vascular PermeabilityCurrent Issues in Molecular BiologyApril 9, 2024Aurélie Joussaume, Chryso Kanthou, Olivier E. Pardo, Lucie Karayan-Tapon, Omar Benzakour, Fatima Dkhissi,Human AXL Antibody/#AF154,"R&D Systems (Minneapolis, MN, USA)",Polyclonal Goat IgG,10 µg/mL MERTK,Human MERTK Antibody/#AF891,R&D Systems,Polyclonal Goat IgG,10 µg/mL PROS1,Anti-Human Protein S/#A038401-2,"Agilent Dako (Santa

(6) Phosphorylation of Ack1 by the Receptor Tyrosine Kinase MerKinases PhosphatasesSeptember 1, 2023Hayashi SY, Craddock BP, Miller WT.affinity resin. Anti-Mer antibody for Western blotting was from R&D Systems, Minneapolis, MN, USA (AF891). Anti-Mer antibody for immunoprecipitation was from abcam, Cambridge, UK (ab184086). DNA constructs. Plasmid

(7) Anti-inflammatory clearance of amyloid-β by a chimeric Gas6 fusion proteinNature medicineSeptember 1, 2022Jung H, Lee SY, Lim S, Choi HR, Choi Y, Kim M, Kim S, Lee Y, Han KH, Chung WS, et al.

(8) Decoding Functional High-Density Lipoprotein Particle Surfaceome InteractionsInternational journal of molecular sciencesAugust 22, 2022Frey K, Goetze S, Rohrer L, von Eckardstein A, Wollscheid B.mouse-anti-human SCARB1 (1:100; clone m1B9, Biolegend, San Diego, CA, USA) and goat-anti-human MERTK (1:40; AF891, Novus, Centennial, CO, USA) were applied overnight at 4 °C. Control slides were incubated either with

(9) Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophagesCell death & diseaseMay 25, 2021Wanke F, Gutbier S, Rümmelin A, Steinberg M, Hughes LD, Koenen M, Komuczki J, Regan-Komito D, Wagage S, Hesselmann J, et al.

(10) A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic TargetCellular and molecular gastroenterology and hepatologyJanuary 1, 2020Tutusaus A, de Gregorio E, Cucarull B, Cristóbal H, Aresté C, Graupera I, Coll M, Colell A, Gausdal G, Lorens JB, et al.antibody (#AF854, mouse; #AF154, human 10 nM; R&D Systems), and MERTK activating antibody (#AF591, mouse; #AF891, human, 10 nM; R&D Systems) or normal Goat IgG Control (AB-108-C; R&D Systems). Cell death in primary

(11) Relevance of placental type I interferon beta regulation for pregnancy successCellular & Molecular ImmunologyDecember 1, 2018Ja-Young Kwon et al.proteins. Antibodies were diluted as follows: 1:200 anti-Axl (AF154, R&D Systems); 1:400 anti-Mer (AF891, R&D Systems); 1:1000 anti-tTBK, 1:500 anti-tIRF3, 1:1000 anti-pIRF3, and 1:1000 anti-tIRF7 (Cell Signaling);

(12) TIM-1 Mediates Dystroglycan-Independent Entry of Lassa VirusJournal of virologyAugust 15, 2018Brouillette RB, Phillips EK, Patel R, Mahauad-Fernandez W, Moller-Tank S, Rogers KJ, Dillard JA, Cooney AL, Martinez-Sobrido L, Okeoma C, et al.anti-hAxl (catalog number AF154), goat anti-hTIM-1 (catalog number AF1750), goat anti-hMer (catalog number AF891), goat anti-hTIM-4 (catalog number AF2929), and goat anti-hTyro3 (catalog number AF859). Mannosylationdependent

(13) Antiphospholipid Antibodies Inhibit Trophoblast Toll-Like Receptor and Inflammasome Negative RegulatorsArthritis & rheumatology (Hoboken, N.J.)June 1, 2018Mulla MJ, Weel IC, Potter JA, Gysler SM, Salmon JE, Peraçoli MTS, Rothlin CV, Chamley LW, Abrahams VM.antibodies to human proteins were used: TYRO3 (#MAB859, R&D Systems); AXL (#AF154, R&D Systems); MERTK (#AF891, R&D Systems); phosphorylated (p) AXL (#9271, Cell Signaling, Danvers, MA); pMERTK (#ab192649, AbCam,

(14) Axl and MerTK receptor tyrosine kinases maintain human macrophage efferocytic capacity in the presence of viral triggersEuropean Journal of ImmunologyMay 1, 2018Aleksander M Grabiec, Anu Goenka, Mark E Fife, Toshifumi Fujimori, Tracy Hussellstimulated as described above or treated with control goat IgG (AB‐108‐C, 5 μg/mL), goat anti‐MerTK (AF891, 2.5 μg/mL) or goat anti‐Axl (AF154, 5 μg/mL) antibodies (all from R&D Systems) in the presence or absence

(15) Human Sertoli cells support high levels of Zika virus replication and persistenceScientific reportsApril 3, 2018Kumar A, Jovel J, Lopez-Orozco J, Limonta D, Airo AM, Hou S, Stryapunina I, Fibke C, Moore RB, Hobman TC.(R&D systems, AF859), Goat anti-Axl antibody (R&D systems, AF154), Goat anti-Mer antibody (R&D systems, AF891), Mouse anti-FGF2 (EMD Millipore, 05-117), Mouse IgG1 isotype control antibody (R&D systems, MAB002),

(16) Protein S and Gas6 induce efferocytosis of HIV-1-infected cellsVirologyFebruary 1, 2018Chua BA, Ngo JA, Situ K, Ramirez CM, Nakano H, Morizono K.

(17) Expression and role of TYRO3 and AXL as potential therapeutical targets in leiomyosarcomaBritish journal of cancerDecember 5, 2017Dantas-Barbosa C, Lesluyes T, Loarer FL, Chibon F, Treilleux I, Coindre JM, Meeus P, Brahmi M, Bally O, Ray-Coquard I, et al.with the following goat polyclonal primary antibodies: anti-TYRO3 (AF859); anti-AXL (AF154); anti-Mer (AF891) all from R&D Systems; or goat IgG isotype control (Novus Biologicals, Cambridge, UK), and a secondary

(18) Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome ActivationJournal of immunology (Baltimore, Md. : 1950)October 15, 2017Cross SN, Potter JA, Aldo P, Kwon JY, Pitruzzello M, Tong M, Guller S, Rothlin CV, Mor G, Abrahams VM.primary Abs against TYRO3 (catalog number MAB859), AXL (catalog number AF154), and MERTK (catalog number AF891; all from R&D Systems). IL-1b levels were evaluated using the anti-human primary Abs against pro–IL-1b

(19) AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flavivirusesProceedings of the National Academy of Sciences of the United States of AmericaFebruary 21, 2017Richard AS, Shim BS, Kwon YC, Zhang R, Otsuka Y, Schmitt K, Berri F, Diamond MS, Choe H.inhibition assays, the indicated cells were preincubated with an anti-AXL (AF154; R&D Systems) or antiMERTK (AF891; R&D Systems) antibody for 20 min at room temperature, infected with replication-competent viruses or

(20) MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammationProceedings of the National Academy of Sciences of the United States of AmericaJune 7, 2016Cai B, Thorp EB, Doran AC, Subramanian M, Sansbury BE, Lin CS, Spite M, Fredman G, Tabas I.

Be the First to Write a Review!

Human Mer Antibody

Mer Antibody

Mer Antibody

Mer Antibody

Mer Antibody

Human Mer Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (26)

Reviews

Human Mer Antibody from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map