Human/Mouse FLIP Antibody AF821 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman/Mouse FLIP Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $429.00Supplier Page View Company Product Page
Catalog NumberAF821
Quantity100 ug (also 25 ug)
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,Immunocytochemistry
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Conjugate/TagUnconjugated
ConcentrationLYOPH
PurityAntigen Affinity-purified
ReactivityHuman,Mouse,Porcine
IsotypeIgG
HostRabbit
TargetFLIP
Antibody TypePrimary Antibodies
ClonalityPolyclonal
ImmunogenKLH-coupled mouse FLIP synthetic peptide, LKQGRRRPLVDLHVELMDKC
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene NameCASP8 and FADD like apoptosis regulator
NCBI Gene AliasesCASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, cFLIP

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cellsCell death & diseaseApril 9, 2021Huangfu J, Hao C, Wei Z, Wormstone IM, Yan H, Fan X.Proteintech), cFLIP (Cat. No. 10394-1-AP, Proteintech, Rosemont, IL), cFLIP for mouse cells and tissue (AF821, R&D System, Minneapolis, MN), Survivin (Cat. 1058-1-AP, Proteintech), CIAP1 (Cat. 66626-1-AP, Proteintech),

(2) Forefront: MiR-34a-Knockout Mice with Wild Type Hematopoietic Cells, Retain Persistent Fibrosis Following Lung InjuryInternational journal of molecular sciencesMarch 23, 2020Bulvik R, Biton M, Berkman N, Breuer R, Wallach-Dayan SB.antibody solution (anti-α-SMA (Cat. No. M0851, DAKO Agilent, Santa Clara, CA, USA) and anti-FLIP (Cat. No. AF821, R&D Systems, Minneapolis, MN, USA)) in PBS-buffered 1% BSA solution, blocked in the blocking reagent

(3) Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cellsPloS oneJanuary 1, 2018English WR, Ireland-Zecchini H, Baker AH, Littlewood TD, Bennett MR, Murphy G.

(4) Survivin, a key player in cancer progression, increases in obesity and protects adipose tissue stem cells from apoptosisCell death & diseaseMay 18, 2017Ejarque M, Ceperuelo-Mallafré V, Serena C, Pachón G, Núñez-Álvarez Y, Terrón-Puig M, Calvo E, Núñez-Roa C, Oliva-Olivera W, Tinahones FJ, et al.#9664, respectively; Cell Signaling Technology, Beverly, MA, USA); anti-tBID and anti-FLIP (AF860 and AF821, respectively; R&D Systems); anti-GAPDH (MA5-15738; Sigma-Aldrich); anti-FAA and anti-Ub (sc-66223 and

(5) Cytoplasmic levels of cFLIP determine a broad susceptibility of breast cancer stem/progenitor-like cells to TRAILMolecular cancerDecember 15, 2015French R, Hayward O, Jones S, Yang W, Clarkson R.by Western blotting. cFLIP antibodies used were purchased from Santa Cruz (5D8) and R and D systems (AF821). Beta Catenin antibody was purchased from BD Biosciences (610154). To quantitate Western data blots

(6) Proapoptotic and survival signaling in the neuroretina at early stages of diabetic retinopathyMolecular visionJanuary 1, 2013Valverde AM, Miranda S, García-Ramírez M, González-Rodriguez Á, Hernández C, Simó R.antibodies were from BD Biosciences PharMingen (San Diego, CA). Anti-Bid (Ref. AF860) and anti-FLIP (Ref. AF821) antibodies were from R&D Systems. Anticleaved (Asp175) caspase-3 antibody (#9661) was purchased from

(7) Infrared radiation confers resistance to UV-induced apoptosis via reduction of DNA damage and upregulation of antiapoptotic proteinsThe Journal of investigative dermatologyMay 1, 2009Jantschitsch C, Majewski S, Maeda A, Schwarz T, Schwarz A.

(8) Synergistic interactions between interferon-gamma and TRAIL modulate c-FLIP in endothelial cells, mediating their lineage-specific sensitivity to thrombotic thrombocytopenic purpura plasma-associated apoptosisBloodJuly 15, 2008Stefanescu R, Bassett D, Modarresi R, Santiago F, Fakruddin M, Laurence J.

(9) Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic isletsDiabetesOctober 1, 2006Maedler K, Schumann DM, Sauter N, Ellingsgaard H, Bosco D, Baertschiger R, Iwakura Y, Oberholzer J, Wollheim CB, Gauthier BR, et al.

(10) Expression of Fas but not Fas ligand on fetal pig beta cellsXenotransplantationSeptember 1, 2004Bai L, Maedler K, Donath M, Tuch BE.

(11) The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cellsThe Journal of biological chemistryJanuary 23, 2004Sade H, Krishna S, Sarin A.

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FLIP Antibody

FLIP Antibody

FLIP Antibody

Human/Mouse FLIP Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (11)

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Human/Mouse FLIP Antibody from R&D Systems, a Bio-Techne Brand

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