IFN-beta Antibody AF814 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIFN-beta Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF814
ApplicationsWestern Blot,Neutralization
TargetIFN-beta
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman
HostGoat
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human IFN¿ß
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nameinterferon beta 1
NCBI Gene AliasesIFB, IFF, IFN-beta, IFNB

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human IFN¿ß in direct ELISAs and Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Therapeutic stress triggers tumor STAT1 acetylation to disarm immunotherapyCell Reports MedicineNovember 18, 2025Po-Hsien Chiu, Kuan-Chen Lai, Hung-Ling Wang, Yao-Wen Chang, Wen-Chi Wu, Tien-Hua Chen, Yu-Shuen Tsai, Jie-Hong Song, Nai-Yun Sun, Gar-Yang Chau, et al.BE0089;RRID:AB_1107769 Human TNF-α Antibody,R&D systems,Cat# AF-210-NA; Human IFN-β Antibody,R&D systems,Cat# AF814;RRID:AB_2122897 Rabbit polyclonal IFITM1 Antibody,Proteintech,Cat# 11727-3-AP;RRID:AB_2122083 Rabbit

(2) The cGAS-STING pathway is a master regulator of OCT4 expression in persistent sarcoma cells and enhances cellular immunotherapy with NK and CIK lymphocytesCancer Immunology, ImmunotherapySeptember 23, 2025Giorgia Giordano, Alessandra Merlini, Federica Capozzi, Giulio Ferrero, Cristina Tucciarello, Shahab Majidi, Simona Comparato, Giulia Mesiano, Elisabetta Liuzzi, Federica Galvagno, et al.immediately before use at a final concentration of 1 μM for 24-h treatments. The IFNβ-neutralizing antibody (AF814, R&D Systems) was stored at − 20 °C and diluted to a final concentration of 0.2 µg/ml for 24-h cell

(3) PRC2-Mediated Epigenetic Suppression of Type I IFN-STAT2 Signaling Impairs Antitumor Immunity in Luminal Breast CancerCancer researchDecember 16, 2022Hong J, Lee JH, Zhang Z, Wu Y, Yang M, Liao Y, de la Rosa R, Scheirer J, Pechacek D, Zhang N, et al.(Invitrogen, #31903)], 0.5 μg/mL for anti-IFNα (R&D Systems, #21100–1), 2 μg/mL for anti-IFNβ (R&D Systems, # AF814), 2 μg/mL for anti-IFNγ (R&D Systems, #MAB2851), 4 μg/mL for anti-IL-29 (R&D Systems, #MAB15981) and

(4) Data supporting the roles of BAP1, STING, and IFN-β in ISGF3 activation in ccRCCData in briefDecember 1, 2022Langbein LE, Sementino E, Zhong Z, Jiang W, Li L, Testa JR, Yang H.

(5) Live imaging of neolymphangiogenesis identifies acute antimetastatic roles of dsRNA mimicsEMBO molecular medicineDecember 7, 2021Olmeda D, Cerezo-Wallis D, Mucientes C, Calvo TG, Cañón E, Alonso-Curbelo D, Ibarz N, Muñoz J, Rodriguez-Peralto JL, Ortiz-Romero P, et al.I IFN blocking assays For type I interferon blocking assays, human IFN‐β blocking antibody (Clone AF814; R&D) and its corresponding isotype (Goat IgG, R&D Systems) were used at a concentration of 0.2 µg/ml.

(6) Single-cell analysis of early antiviral gene expression reveals a determinant of stochastic IFNB1 expressionIntegrative biology : quantitative biosciences from nano to macroNovember 13, 2017Doğanay S, Lee MY, Baum A, Peh J, Hwang SY, Yoo JY, Hergenrother PJ, García-Sastre A, Myong S, Ha T.was blocked by addition of 10 μg/ml of anti-IFN-α (Abcam, ab20200), 10 μg/ml anti-IFN-β (R&D systems, AF814), 10 μg/ml anti-IFN-λ (R&D Systems, MAB15981), and 5 μg/ml anti-IFNAR chain 2 (PBL InterferonSource,

(7) Sangassou virus, the first hantavirus isolate from Africa, displays genetic and functional properties distinct from those of other murinae-associated hantavirusesJournal of virologyApril 1, 2012Klempa B, Witkowski PT, Popugaeva E, Auste B, Koivogui L, Fichet-Calvet E, Strecker T, Ter Meulen J, Krüger DH.proteins were incubated with 1 ␮g/well of anti-IFN-␭1 or anti-IFN-␤ antibodies (catalog no. AF1598 or AF814, respectively; R&D Systems) for 1 h at room temperature. The resulting mixture was then added to A549 cells

(8) Dobrava-Belgrade hantavirus from Germany shows receptor usage and innate immunity induction consistent with the pathogenicity of the virus in humansPloS oneJanuary 1, 2012Popugaeva E, Witkowski PT, Schlegel M, Ulrich RG, Auste B, Rang A, Krüger DH, Klempa B.recombinant proteins were incubated with 1 µg/well of anti-IFN-λ1 or anti-IFN-β (R&D Systems, AF1598 and AF814, respectively) for 1 hour at room temperature. The resulting mixture was then added to A549 cells and

(9) Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-γPLoS pathogensApril 1, 2011Knoblach T, Grandel B, Seiler J, Nevels M, Paulus C.IFN-c (R&D Systems, no. 285-IF) for various durations. Neutralizing goat antibodies to human IFN-b (no. AF814) or IFN-c (no. AF16 April 2011 | Volume 7 | Issue 4 | e1002016 HCMV IE1 Elicits IFN-c-Like Response was

(10) New World hantaviruses activate IFNlambda production in type I IFN-deficient vero E6 cellsPloS oneJune 17, 2010Prescott J, Hall P, Acuna-Retamar M, Ye C, Wathelet MG, Ebihara H, Feldmann H, Hjelle B.the indicated concentrations of anti-IL29, anti-IL28A, or anti-IFNβ (R&D Systems, AF1598, AF1587 or AF814, respectively) for 0.5 h at room temp. The resulting mixture was then added to cells and incubated for

(11) The LIM-homeodomain transcription factor LMX1B regulates expression of NF-kappa B target genesExperimental cell researchJanuary 1, 2009Rascle A, Neumann T, Raschta AS, Neumann A, Heining E, Kastner J, Witzgall R.

(12) Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophagesThe Journal of general virologySeptember 1, 2004Emori Y, Ikeda T, Ohashi T, Masuda T, Kurimoto T, Takei M, Kannagi M.

(13) TLR3 can directly trigger apoptosis in human cancer cells"Journal of immunology (Baltimore, Md. : 1950)"January 1, 0001"Salaun B, Coste I, Rissoan MC, Lebecque SJ, Renno T."

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IFN-beta Antibody

IFN-beta Antibody

IFN-beta Antibody

IFN-beta Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (13)

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IFN-beta Antibody from R&D Systems, a Bio-Techne Brand

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