LIX Antibody AF433 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemLIX Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberAF433
NCBI Gene AliasesSCYB5, GCP-2, Cxcl6, ENA-78, Scyb6, AMCF-II, LIX, Scyb5
ApplicationsFlow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Neutralization
ReactivityHuman,Mouse
TargetLIX
HostGoat
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
NCBI Full Gene NameC-X-C motif chemokine ligand 5, chemokine (C-X-C motif) ligand 5
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant mouse LIX, Val45-Ala118, Accession # P50228
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse LIX in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human GCP-2, recombinant rat (rr) CINC-2 alpha, rrCINC-2ß, recombinant mouse (rm) KC, and rmMIP-2 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) GLI2 Facilitates Tumor Immune Evasion and Immunotherapeutic Resistance by Coordinating WNT and Prostaglandin SignalingCancer ResMay 2, 2025Nicholas C. DeVito, Y-Van Nguyen, Michael Sturdivant, Michael P. Plebanek, Kaylee A. Villarreal, Nagendra Yarla, Vaibhav Jain, Michael Aksu, Georgia M. Beasley, Balamayooran Theivanthiran, et al.(invitrogen, PA5–40518, RRID:AB_2607990), FoxC2 (Proteintech, 23066–1-AP, RRID:AB_2879204), CXCL5 (Novus/R&D, AF433, RRID:AB_2086589), Vimentin (Santa Cruz, sc-373717, RRID:AB_10917747), Actin (Cell Signaling, 3700S,

(2) GLI2 Facilitates Tumor Immune Evasion and Immunotherapeutic Resistance by Coordinating WNT and Prostaglandin SignalingCancer ResearchMay 2, 2025Nicholas C. DeVito, Y-Van Nguyen, Michael Sturdivant, Michael P. Plebanek, Kaylee A. Villarreal, Nagendra Yarla, Vaibhav Jain, Michael Aksu, Georgia M. Beasley, Balamayooran Theivanthiran, et al.(invitrogen, PA5–40518, RRID:AB_2607990), FoxC2 (Proteintech, 23066–1-AP, RRID:AB_2879204), CXCL5 (Novus/R&D, AF433, RRID:AB_2086589), Vimentin (Santa Cruz, sc-373717, RRID:AB_10917747), Actin (Cell Signaling, 3700S,

(3) Tumor Microenvironment Responsive CD8(+) T Cells and Myeloid-Derived Suppressor Cells to Trigger CD73 Inhibitor AB680-Based Synergistic Therapy for Pancreatic CancerAdvanced science (Weinheim, Baden-Wurttemberg, Germany)November 1, 2023Chen Q, Yin H, He J, Xie Y, Wang W, Xu H, Zhang L, Shi C, Yu J, Wu W, et al.(Abcam, ab209775), granzyme B (Abcam, ab4059), CXCR2 (Proteintech, 19538‐1‐AP), CXCL5 (R&D Systems, AF433), LY6G (Servicebio, GB11229), Ki‐67 (CST, 9129), and cleaved caspase 3 (CST, 9664), followed by biotinylated

(4) A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapyThe Journal of clinical investigationMay 1, 2020Theivanthiran B, Evans KS, DeVito NC, Plebanek M, Sturdivant M, Wachsmuth LP, Salama AK, Kang Y, Hsu D, Balko JM, et al.anti-HSP70, mouse mAb (Santa Cruz Biotechnology, sc-66048); anti-CXCL5, goat polyclonal Ab (R&D Systems, AF433); anti-CXCL5, rabbit polyclonal Ab (LSBio, LS-c293780); anti–YAP/TAZ, rabbit mAb (Cell Signaling Technology,

(5) Cigarette smoke primes the pulmonary environment to IL-1α/CXCR-2-dependent nontypeable Haemophilus influenzae-exacerbated neutrophilia in miceJournal of immunology (Baltimore, Md. : 1950)September 15, 2014Nikota JK, Shen P, Morissette MC, Fernandes K, Roos A, Chu DK, Barra NG, Iwakura Y, Kolbeck R, Humbles AA, et al.

(6) Comprehensive assessment of chemokine expression profiles by flow cytometryThe Journal of clinical investigationMarch 1, 2010Eberlein J, Nguyen TT, Victorino F, Golden-Mason L, Rosen HR, Homann D.

(7) Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma productionProceedings of the National Academy of Sciences of the United States of AmericaApril 7, 2009Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA Jr, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, et al.

(8) Tumor-intrinsic NLRP3-HSP70-TLR4 axis drives premetastatic niche development and hyperprogression during anti-PD-1 immunotherapyScience translational medicineJanuary 1, 0001"Theivanthiran B, Yarla N, Haykal T, Nguyen YV, Cao L, Ferreira M, Holtzhausen A, Al-Rohil R, Salama AKS, Beasley GM, et al."

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LIX Antibody

LIX Antibody

LIX Antibody

LIX Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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LIX Antibody from R&D Systems, a Bio-Techne Brand

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