Integrin alpha E/CD103 Antibody AF1990 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIntegrin alpha E/CD103 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF1990
NCBI Gene AliasesCD103, HUMINAE, aM290, alpha-M290, alpha-E1, A530055J10
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,CyTOF-reported,CyTOF-ready
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Quantity100 ug (also 25 ug)
HostGoat
ReactivityMouse,Transgenic Mouse
IsotypeIgG
TargetIntegrin alpha E/CD103
NCBI Full Gene Nameintegrin alpha E, epithelial-associated, integrin subunit alpha E
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse Integrin alpha E/CD103, Phe20-Arg1113, Accession # Q60677
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
PurityAntigen Affinity-purified
ConcentrationLYOPH

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse Integrin alpha E/CD103 in direct ELISAs and Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) FAP-CD40 and PD1-IL2v combination therapy reprograms immunologically cold tumors through de novo intratumoral T cell-dendritic cell clustersJournal for ImmunoTherapy of CancerMay 28, 2026Thuy Trinh Nguyen, Harold Gómez, Mechthild Lutge, Emilio Yángüez, Tamara Hüsser, Sina Nassiri, Christine Trumpfheller, Sara Colombetti, Laura Codarri Deak, Pablo Umaña, et al.“4C8MS”, Novus, NB110-68136AF750). Unconjugated Clec9A (1:300, R&D, #AF6776) and CD103 (1:800, R&D, #AF1990) antibodies were labeled using CF594 (Biotium, #92257) and CF633 (Biotium, #92257) conjugation kits,

(2) Agonistic anti-CD40 antibody treatment converts resident regulatory T cells into activated type 1 effectors within the tumor microenvironmentImmunityApril 14, 2026Vivien I. Maltez, Charu Arora, Kyle P. Gribbin, Breanna Caruso, Margaret E. Haerr, Rina Sor, Qiaoshi Lian, Katie E. Blise, Shamilene Sivagnanam, Rosalie C. Sears, et al.101217); CD11c (N418; AF647, BioLegend, Cat # 117312); CD103 (Itgae; unconjugated, R&D Systems, Cat # AF1990); MHC-II (M5/114.152; AF700, BioLegend, Cat # 107622); NFAT1 (D43B1; unconjugated, CST, Cat # 5861S);

(3) Expression of CD103 facilitates localization and activation of CD4+ T cells within Mycobacterium tuberculosis lung-lesionsMucosal ImmunologyApril 1, 2026Thomas Lindenstrøm, Nafsika Panagiotopoulou, Sara B. Cohen, Paula Torres Rodriguez, Joshua S. Woodworth, Mari Morikawa, Mehnaz Halima, Camilla Myhre Maymann, Tu Hu, Sylvia M. Stull, et al.D57.2.2E; Cell Signaling Technology, Cat#99457), CD103–conjugated in house (polyclonal; R&D Systems, Cat#AF1990), CD68–mFluor Violet 610 (clone FA-11; Novus Biologicals, Cat#NBP2–33337MFV610), CD4–conjugated in house

(4) NGO ameliorates psoriasis by modulating mitochondrial function and suppressing pSTAT3–IL-17–expressing CD8+ TRM cellsJournal of NanobiotechnologyJanuary 16, 2026Tae Ho Kim, Chae Rim Lee, Kyoung Min Choi, Soon Won Choi, Seon-Yeong Lee, A. Ram Lee, Jung Won Choi, Young Mi Moon, Joonhyuck Park, Haeyoun Choi, et al.antibodies against the surface markers CD8 (NBP1-49045; Novus Biologicals, Littleton, CO, USA) and CD103 (AF1990; R&D Systems, Minneapolis, MN, USA). To detect key functional proteins, additional staining was performed

(5) Resident memory T cell development is gradual and shows AP-1 gene expression in mature cellsJCI InsightJune 23, 2025Neal P. Smith, Yu Yan, Youdong Pan, Jason B. Williams, Kasidet Manakongtreecheep, Shishir M. Pant, Jingxia Zhao, Tian Tian, Timothy Pan, Claire Stingley, et al.μg/mL; LI-COR Biosciences) and antibodies against CD8a (83012BC; Cell Signaling Technologies), CD103 (AF1990; R&D Systems), CD11c (64675BC; Cell Signaling Technologies), JunB (3753; Cell Signaling Technologies),

(6) The XCL1/XCR1 axis is upregulated in type 1 diabetes and aggravates its pathogenesisJCI insightFebruary 27, 2025Tondello C, Bender C, Golden GJ, Puppe D, Blickberndt E, Bayer M, Buchmann GK, Pfeilschifter J, Bachmann M, Hintermann E, et al.antibodies used were rat anti-CD8b (1:100, BioLegend, 126602), goat anti-CD103 (1:300, R&D Systems, AF1990), Armenian hamster anti-CD11c (1:200, Invitrogen, 14-0114-82), and rabbit anti-insulin (1:4,000, Abcam,

(7) A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infectionNatureJuly 1, 2024Bosch M, Kallin N, Donakonda S, Zhang JD, Wintersteller H, Hegenbarth S, Heim K, Ramirez C, Fürst A, Lattouf EI, et al.anti-I-A/I-E (MHC class II) (clone M5/114.15.2, 107622, 1:200, Biolegend) and anti-CD103 (goat polyclonal, AF1990, 1:200, R&D Systems) followed by anti-goat IgG (donkey polyclonal, 705-625-147, 1:500, Jackson ImmunoResearch).

(8) Targeting AXL induces tumor-intrinsic immunogenic response in tyrosine kinase inhibitor-resistant liver cancerCell death & diseaseFebruary 3, 2024Xie Y, Wu H, He Y, Liu L, Huang IB, Zhou L, Lin CY, Leung RW, Loh JJ, Lee TK, et al.primary antibodies (AXL (1:500, Abcam, ab227871); CD8α (1:500, Abcam, ab217344); CD103 (1:50, R&D System, AF1990)). The sections were then washed thoroughly and incubated with Opal polymer HRP Ms+Rb (ARH1001EA, Akoya

(9) Guidelines for visualization and analysis of DC in tissues using multiparameter fluorescence microscopy imaging methodsEuropean journal of immunologyNovember 1, 2023Bayerl F, Bejarano DA, Bertacchi G, Doffin AC, Gobbini E, Hubert M, Li L, Meiser P, Pedde AM, Posch W, et al.

(10) Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinomaCancer cellMay 8, 2023Gaglia G, Burger ML, Ritch CC, Rammos D, Dai Y, Crossland GE, Tavana SZ, Warchol S, Jaeger AM, Naranjo S, et al.,Cell Signaling Technology,Clone D4W2Z; Cat# 98941; RRID: AB_2756376 t-CyCIF: anti-mouse CD103,R&D Systems,Clone Polyclonal; Cat# AF1990; RRID: AB_2128618 t-CyCIF: anti-mouse CD11c,Cell Signaling Technology,Clone D1V9Y; Cat# 97585; RRID:

(11) CX3CR1 deficiency leads to impairment of immune surveillance in the epididymisCellular and molecular life sciences : CMLSDecember 23, 2022Barrachina F, Ottino K, Tu LJ, Soberman RJ, Brown D, Breton S, Battistone MA.14–4801, eBioscience, San Diego, CA), goat polyclonal antibody against integrin alpha E/CD103 (4 μg/mL; AF1990, R&D Systems, Minneapolis, MN), rabbit polyclonal antibody against connexin 43 (gap junction alpha-1

(12) Therapeutic KRAS(G12C) inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancersScience advancesJuly 22, 2022Mugarza E, van Maldegem F, Boumelha J, Moore C, Rana S, Llorian Sopena M, East P, Ambler R, Anastasiou P, Romero-Clavijo P, et al.no. 89Y,CD45,30-F11,Fluidigm,3089005B 141Pr,aSMA,1A4,Fluidigm,3141017D 142Nd,MHCcII,M5/114.15.2,BioLegend,107637* 144Nd,MHCcI,28-14-8,Fluidigm,3144016C 146Nd,F480,(CI:A3-1),Bio-Rad,MCA497GA* 147Sm,CD68,FA-11,BioLegend,137002* 150Nd,CD44,IM7,Fluidigm,3150018B 152Sm,CD3e,145-2C11,Fluidigm,3152004B 153Eu,PDL1,10F.9G2,Fluidigm,3153016B 158Gd,Foxp3,FJK-16s,Fluidigm,3158003A 161Dy,CD103,AF1990G,R&D Systems,AF1990* 165Ho,TIGIT,4D4/mTIGIT,BioLegend,156102* 166Er,PD1,29F.1A12,BioLegend,135202* 167Er,NKp46,29A1.4,Fluidigm,3167008B 168Er,CD8a,53-6.7,Fluidigm,3168003B 169Tm,CD4,RM4-5,BioLegend,100561* 170Er,CXCL9,MIG-2F5.5,BioLegend,515602* 171Yb,Granzyme

(13) Epithelial colonization by gut dendritic cells promotes their functional diversificationImmunityJanuary 11, 2022Rivera CA, Randrian V, Richer W, Gerber-Ferder Y, Delgado MG, Chikina AS, Frede A, Sorini C, Maurin M, Kammoun-Chaari H, et al.unconjugated, dilution for cryosections – 1 to 100; dilution for whole-mount – 1 to 50",R&D systems,Cat#AF1990; RRID: AB_2128618 "Armenian Hamster IgG monoclonal anti-CD103, Alexa 488 conjugated, clone 2E7, dilution

(14) Macrophages Maintain Epithelium Integrity by Limiting Fungal Product AbsorptionCellOctober 15, 2020Chikina AS, Nadalin F, Maurin M, San-Roman M, Thomas-Bonafos T, Li XV, Lameiras S, Baulande S, Henri S, Malissen B, et al.unconjugated, dilution for cryosections – 1 to 100; dilution for whole-mount – 1 to 50",R&D systems,Cat# AF1990; RRID: AB_2128618 "Rat IgG2a monoclonal anti-CD64, unconjugated, clone AT152-9, dilution for cryosections

(15) NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune ControlCellFebruary 22, 2018Böttcher JP, Bonavita E, Chakravarty P, Blees H, Cabeza-Cabrerizo M, Sammicheli S, Rogers NC, Sahai E, Zelenay S, Reis e Sousa C.(GB11),Biolegend,515408 CD31 AF647 (clone Mec13.3),Biolegend,102515 CD103 (Polyclonal goat),R&D Systems,AF1990 Collagen IV (Polyclonal rabbit),Abcam,Ab6586 ,, Bacterial and Virus Strains,Bacterial and Virus Strains,Bacterial

(16) Dependence of Glomerulonephritis Induction on Novel Intraglomerular Alternatively Activated Bone Marrow-Derived Macrophages and Mac-1 and PD-L1 in Lupus-Prone NZM2328 MiceJournal of immunology (Baltimore, Md. : 1950)April 1, 2017Sung SJ, Ge Y, Dai C, Wang H, Fu SM, Sharma R, Hahn YS, Yu J, Le TH, Okusa MD, et al.

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8/23/2019R&D Integrin Alpha E Antibody for ImmunofluorescenceDr. Efstathios StamatiadesAn excellent goat polyclonal antibody against mouse Itgae.

Mouse Integrin alpha E/CD103 Antibody

Integrin alpha E/CD103 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (16)

Reviews

Integrin alpha E/CD103 Antibody from R&D Systems, a Bio-Techne Brand

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