eIF4B Antibody 3592S from Cell Signaling Technology

Product Specs
ItemeIF4B Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number3592S
Quantity100 µl
ApplicationsW
ReactivityH, M, R, Mk
TargeteIF4B
HostRabbit
NCBI Gene AliasesEIF-4B, PRO1843
NCBI Full Gene Nameeukaryotic translation initiation factor 4B
ClonalityPolyclonal
Research AreaTranslational Control
Molecular Weight80

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Phosphoproteomics identification of ERK-dependent activation of Rps6kb1 in cardiac hypertrophyJCI InsightFebruary 23, 2026Chao Li, Pengfei Zhang, Kai Zhang, Jane A. Cook, Weidan Song, Megan Virostek, Lily A. Slotabec, Nadiyeh Rouhi, Mohammed Hazari, Michael I. Adenawoola, et al.(Santa Cruz Biotechnology, sc-40), HA (Cell Signaling Technology, 3724), eIF4B (Cell Signaling Technology, 3592), p-eIF4B S422 (Cell Signaling Technology, 3591), p-eIF4B S406 (Cell Signaling Technology, 5399), Acta1

(2) Host Translational Control by Stress Granules Promotes Mycobacterium tuberculosis PathogenesisMedComm (2020)November 10, 2025Jaewhan Kim, Sang‐Hun Son, Ji‐Ae Choi, Junghwan Lee, Seoyeon Jo, Soo‐Na Cho, Doan Tam Nguyen, Doyi Son, Kee K. Kim, Chang‐Hwa Songanti‐Astrin (Proteintech, 14726‐1‐AP), rabbit anti‐CoxIV (abcam, ab16056), rabbit anti‐Eif4b (CST, 3592), rabbit anti‐Eif4b‐pS406 (CST, 5399), rabbit anti‐G3bp2 (CST, 31799), rabbit anti‐LC3 (MBL, PM036),

(3) Tks5 interactome reveals endoplasmic‐reticulum‐associated translation machinery in invadosomesThe FEBS JournalJuly 24, 2025Léa Normand, Benjamin Bonnard, Margaux Sala, Sylvaine Di Tommaso, Cyril Dourthe, Anne‐Aurélie Raymond, Jean‐William Dupuy, Luc Mercier, Jacky G. Goetz, Violaine Moreau, et al.TA500288) was purchased from OriGene Technologies, Inc (Rockville, MD, USA). Anti‐EIF4B (catalog number 3592) was purchased from Cell Signaling Technology (Danvers, MA, USA). Secondary antibodies for immunofluorescence

(4) Combination of in vivo and in vitro phosphoproteomics determines the PP2A target repertoire on proteome scaleCell Reports MethodsJuly 21, 2025Melanie Brunner, Zehan Hu, Heidy Elkhaligy, Gloria Lampo, Carole Roubaty, Christine Vionnet, Devanarayanan Siva Sankar, Sean J. McIlwain, Stéphanie Kaeser-Pebernard, Yongna Xing, et al.monoclonal anti MYPT1,Santa Cruz Biotech,Cat# sc-514261 Rabbit polyclonal anti EIF4B,Cell Signaling,Cat# 3592; RRID:AB_2293388 Rabbit polyclonal anti EIF4B pS422,Cell Signaling,Cat# 3591; RRID:AB_2097522 Mouse

(5) Intestinal Gastrin/CCKBR Axis Protects against Type 2 Diabetes by Reducing Intestinal Glucose Absorption through the PI3K/Akt/eIF4B Signaling PathwayAdvanced ScienceFebruary 14, 2025Xue Liu, Xing Liu, Yunpeng Liu, Anxiong Long, Wei Liu, Shiyun Sun, Shuaibing Lu, Xianxian Wu, Xiaodi Jia, Pedro A Jose, et al.(#13857), PI3K (#4263), p‐AKT (#9271), ATK (#9272), p‐S6K1(9205), S6K1(9202) p‐eIF4B (#3591), eIF4B (#3592), and PYY (#24895) were purchased from Cell Signaling Technology, Inc. (Danvers, MA, USA). CCKBR (sc‐166690),

(6) Hepatovirus translation requires PDGFA-associated protein 1, an eIF4E-binding protein regulating endoplasmic reticulum stress responsesScience AdvancesNovember 22, 2024Takayoshi Shirasaki, Erik Lenarcic, Ichiro Misumi, Ling Xie, William G. Fusco, Bryan Yonish, Anshuman Das, Hyejeong Kim, Craig E. Cameron, Mélissa Léger-Abraham, et al.#14793; anti-GFP, Santa Cruz sc-9996; anti-eIF4G, CST #2498; anti-eIF4A, CST #2013; anti-eIF4B, CST #3592; anti-eIF4E, CST #9742; anti-eIF1AX, Proteintech #11649-2-AP; anti-eIF5B, Proteintech #13527-1-AP; anti-4EBP1,

(7) Eukaryotic initiation factor 4B is a multi-functional RNA binding protein that regulates histone mRNAsNucleic acids researchOctober 28, 2024Quintas A, Harvey RF, Horvilleur E, Garland GD, Schmidt T, Kalmar L, Dezi V, Marini A, Fulton AM, Pöyry TAA, et al.were subjected to SDS–PAGE and western blot analysis. Primary antibodies used were eIF4B (CST, no. 3592), Daxx (Millipore, no. 07-471), PABP (CST, no. 4992), eIF4A1 (Abcam, no. ab31217), eIF4A2 (Abcam, no.

(8) The lncRNAMALAT1-WTAP axis: a novel layer of EMT regulation in hypoxic triple-negative breast cancerCell Death DiscoveryJune 11, 2024Martina Dragonetti, Chiara Turco, Anna Benedetti, Frauke Goeman, Mattia Forcato, Stefano Scalera, Matteo Allegretti, Gabriella Esposito, Francesco Fazi, Giovanni Blandino, et al.overnight at +4 °C. For eIF4B IP, were employed the following ChIP-grade antibody from Cell Signaling: #3592. After immunoprecipitation, beads were washed four times with 1 ml of ice-cold NT2 buffer and then resuspended

(9) Viral PIC-pocketing: RSV sequestration of translational preinitiation complexes into bi-phasic biomolecular condensatesJournal of VirologyMarch 19, 2024Fatoumatta Jobe, James T. Kelly, Jennifer Simpson, Joanna Wells, Stuart D. Armstrong, Matt Spick, Emily Lacey, Leanne Logan, Nophar Geifman, Philippa Hawes, et al.anti-eIF4G (2467), anti-eIF4E (2067), anti-eIF3A (3411), anti-eIF4A (2013), anti-eIF4A1 (2490), anti-eIF4B (3592), anti-eIF4H (3469), and anti-GAPDH (5174) were obtained from Cell Signalling Technology (CST). Mouse

(10) Complex CDKL5 translational regulation and its potential role in CDKL5 deficiency disorderFrontiers in Cellular NeuroscienceOctober 30, 2023Valeria Ruggiero, Claudio Fagioli, Stefano de Pretis, Valerio Di Carlo, Nicoletta Landsberger, Daniele Zacchettiwere αtubulin (Cell Signaling, 3873); CDKL5 (Santa Cruz Biotech., Sc-376314); eIF4B (Cell Signaling, 3592); and XIAP (Cell Signaling, 14334). Detection and quantification of chemiluminescence signals were performed

(11) Genetic Ablation of LAT1 Inhibits Growth of Liver Cancer Cells and Downregulates mTORC1 SignalingInternational journal of molecular sciencesMay 24, 2023Kim SY, Ong Q, Liao Y, Ding Z, Tan AQL, Lim LTR, Tan HM, Lim SL, Lee QY, Han W.p-S6RP (#4858, Cell Signaling), eIF2a (#9722, Cell Sigaling), p-eIF2a (#3398, Cell Signaling), eIF4b (#3592, Cell Signaling), p-eIF4b (#3591, Cell Signaling), GAPDH (sc-32233, Santa Cruz Biotechnology, Dallas,

(12) Implications of differential transcription start site selection on chronic myeloid leukemia and prostate cancer cell protein expressioniScienceDecember 22, 2022Surani AA, Spriggs KA, Ufer C, Polytarchou C, Montiel-Duarte C.,Cell Signaling Technology,Cat#2490; RRID:AB_823487 Rabbit Polyclonal anti-eIF4B,Cell Signaling Technology,Cat#3592; RRID:AB_2293388 Rabbit monoclonal anti-eIF4E (clone C46H6),Cell Signaling Technology,Cat#2067; RRID:AB_2097675 Rabbit

(13) The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesisMolecular cellSeptember 1, 2022Ali ES, Lipońska A, O'Hara BP, Amici DR, Torno MD, Gao P, Asara JM, Yap MF, Mendillo ML, Ben-Sahra I.p44/42 MAPK (Erk1/2) Antibody,Cell Signaling Technology,Cat# 9102S; RRID: AB_330744 eIF4B Antibody,Cell Signaling Technology,Cat# 3592; AB_2293388 eIF4A (C32B4) Rabbit mAb,Cell Signaling Technology,Cat#2013; RRID:AB_2097363 DYKDDDDK

(14) MKK6 deficiency promotes cardiac dysfunction through MKK3-p38γ/δ-mTOR hyperactivationeLifeAugust 16, 2022Romero-Becerra R, Mora A, Manieri E, Nikolic I, Santamans AM, Montalvo-Romeral V, Cruz FM, Rodríguez E, León M, Leiva-Vega L, et al.phospho-eEF2 (Thr56) (#2331S), phosphor-eIF4G (Ser1108) (#2441S), phospho-eIF4B (Ser422) (#6591S), eIF4B (#3592S), phospho-4EBP1 (Thr37/46) (#9459S), 4EBP1 (#9452), and DEPTOR (D9F5) (#11,816) (Cell Signaling Technology);

(15) Rapamycin maintains the primordial follicle pool and protects ovarian reserve against cyclophosphamide-induced damageJournal of Reproduction and DevelopmentAugust 1, 2022Xiuying CHEN, Zhijing TANG, Haiyun GUAN, Hexia XIA, Chao GU, Yan XU, Bin LI, Wei ZHANG(S2448) (5536), p70S6K (2708), p-p70S6K (T389) (9234), rpS6 (2217), p-rpS6 (S240/244) (5364), eIF4B (3592), p-eIF4B (S422) (3591), APAF-1 (8969), cleaved caspase 3 (9664), caspase 3 (9662), and β-tubulin (2128)

(16) MALAT1-dependent hsa_circ_0076611 regulates translation rate in triple-negative breast cancerCommunications biologyJune 16, 2022Turco C, Esposito G, Iaiza A, Goeman F, Benedetti A, Gallo E, Daralioti T, Perracchio L, Sacconi A, Pasanisi P, et al.boiled for 5 min at 95 °C. Antibodies anti-PTBP1 (Cell Signaling: #72669), anti-EIF4B (Cell Signaling: #3592), anti-EIF4G (Cell Signaling: #2469), anti-SRSF1 (Santa Cruz: SF2/ASF96 sc-33652) and anti-Fibrillarin

(17) Translational Regulation by hnRNP H/F Is Essential for the Proliferation and Survival of GlioblastomaCancersMarch 2, 2022Le Bras M, Gorelick N, Pautet S, Tyler B, Manenti S, Skuli N, Millevoi S, Cammas A.SNAIL (1:1000, Cell signaling 3879S), eIF4G (1/1000, Santa Cruz sc-4373), eIF4B (1:1000, Cell signaling 3592), eIF4H (1:1000, Cell signaling 3469), 4E-BP (1:1000, Cell signaling 9644S), GAPDH (1:1000, Santa Cruz

(18) RSK1 SUMOylation is required for KSHV lytic replicationPLoS pathogensDecember 1, 2021Liu Z, Liu C, Wang X, Li W, Zhou J, Dong P, Xiao MZX, Wang C, Zhang Y, Fu J, et al.viral infection. Methods Antibodies and chemicals Anti-RxRxxS*/T*(#10001S), RSK1 (#9333S), RSK2 (#5528S), p-eIF4B (#3591S), eIF4B (#3592S) antibodies were ordered from Cell Signaling Technology. HRP anti-HA (#901519), HRP anti-Flag (#637311)

(19) H19X-encoded miR-322(424)/miR-503 regulates muscle mass by targeting translation initiation factorsJournal of cachexia, sarcopenia and muscleDecember 1, 2021Liang R, Shen X, Wang F, Wang X, DesJarlais A, Syed A, Saba R, Tan Z, Yu F, Ji X, et al.(1:1000; NBP1‐31045, Novus Biologicals), anti‐eIF4G (1:2000; 2498, Cell Signaling), anti‐eIF4B (1:1000; 3592, Cell Signaling), anti‐eIF2B5 (1:1000; 3595, Cell Signaling), and anti‐phospho‐eIF2α (Ser51) (1:1000;

(20) Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer''s diseaseCell death & diseaseAugust 4, 2021Bettegazzi B, Sebastian Monasor L, Bellani S, Codazzi F, Restelli LM, Colombo AV, Deigendesch N, Frank S, Saito T, Saido TC, et al.Antibody,Product Number,Concentration,Blocking,Producer eIF4B,3592,1:1000,5% BSA in TBST,Cell Signaling Technology S504-eIF4B,Ab75823,1:3000,5% BSA in TBST,Abcam BACE,5606,1:1000,5%

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eIF4B Antibody

eIF4B Antibody from Cell Signaling Technology

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Cell Signaling Technology

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eIF4B Antibody from Cell Signaling Technology

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