MSH6 (D60G2) XP ® Rabbit mAb 5424S from Cell Signaling Technology

Product Specs
ItemMSH6 (D60G2) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $371.00 Inquire
Catalog Number5424S
Quantity100 µl
ApplicationsW, IF-IC
ReactivityH, Mk
TargetMSH6
HostRabbit
NCBI Gene AliasesGTBP, GTMBP, HNPCC5, HSAP, LYNCH5, MMRCS3, MSH-6, p160
ClonalityMonoclonal
NCBI Full Gene NamemutS homolog 6
Research AreaCell Cycle / Checkpoint Control
IsotypeIgG
CloneD60G2
Molecular Weight160

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Binding of α-synuclein to ACO2 promotes progressive mitochondrial dysfunction in Parkinson's disease modelsRedox BiologyNovember 1, 2024Jie Jiao, Ge Gao, Junge Zhu, Chaodong Wang, Lei Liu, Hui Yangin 0.01 M PBS for 10 min at room temperature. Following a blocking step with 5 % normal goat serum (5424; Cell Signaling Technology) for 1 h, the cells were incubated overnight with primary antibodies at 4

(2) 4-Oxo-2-Nonenal- and Agitation-Induced Aggregates of α-Synuclein and Phosphorylated α-Synuclein with Distinct Biophysical Properties and Biomedical ApplicationsCellsApril 24, 2024Tie Wang, Weijin Liu, Qidi Zhang, Jie Jiao, Zihao Wang, Ge Gao, Hui Yang0.3% TritonX-100 in 0.01 M PBS for 10 min at room temperature, incubated for 60 min in 10% goat serum (5424; Cell Signaling Technology, Inc., Danvers, MA, USA), followed by incubation overnight at 4 °C with an

(3) CDK-independent role of D-type cyclins in regulating DNA mismatch repairMolecular CellApril 4, 2024Gergely Rona, Bearach Miwatani-Minter, Qingyue Zhang, Hailey V. Goldberg, Marc A. Kerzhnerman, Jesse B. Howard, Daniele Simoneschi, Ethan Lane, John W. Hobbs, Elizabeth Sassani, et al.(1:1000),Cell Signaling Technology,"Cat#12988S, RRID: AB_2750881" MSH6 (1:1000),Cell Signaling Technology,"Cat#5424S, RRID: AB_10695802" Myc (1:2000),Cell Signaling Technology,"Cat#2278S, RRID: AB_490778" OGG1 (1:1000),Novus Biologicals

(4) Establishment and Characterization of Multi-Drug Resistant p53-Negative Osteosarcoma SaOS-2 SublineDiagnostics (Basel, Switzerland)August 11, 2023Boichuk S, Bikinieva F, Valeeva E, Dunaev P, Vasileva M, Kopnin P, Mikheeva E, Ivoilova T, Mustafin I, Galembikova A.cleaved caspase-3 (cat. no. 9661S), p-BRCA1 S1524 (cat. no. 9009S), MSH2 (cat. no. 2017T), MSH6 (cat. no. 5424), Chk1 (cat. no. 2360S), Chk2 (cat. no. 6334P), Topoisomerase IIα (cat. no. 12286T), Rad51 (cat. no.

(5) BET protein inhibition sensitizes glioblastoma cells to temozolomide treatment by attenuating MGMT expressionCell death & diseaseDecember 13, 2022Tancredi A, Gusyatiner O, Bady P, Buri MC, Lomazzi R, Chiesi D, Messerer M, Hegi ME.(Bioconcept, 8H10D10. 1:10,000), anti-MGMT (R&D systems, AF3794-SP, 1:4000), anti-MSH6 (Cell Signaling, #5424 S, 1:4000), anti-MSH2 (Cell Signaling, #2017S, 1:4000). Membranes were washed 5 min x3 in TBS-T at RT,

(6) A Novel Pseudogene Methylation Signature to Predict Temozolomide Outcome in Non-G-CIMP GlioblastomasJournal of oncologyJanuary 1, 2022Li B, Wang J, Liu F, Li R, Hu W, Etcheverry A, Aubry M, Mosser J, Yin A, Zhang X, et al.MPG (Proteintech, 11481-2-AP), p-p65 (CST, #3033), MLH1 (CST, #3515), MSH2 (CST, #2017), MSH6 (CST, #5424), and β-actin (CST, #3700). The expression of β-actin was used as the internal control. The intensity

(7) Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repairCell reportsDecember 7, 2021Barroso-González J, García-Expósito L, Galaviz P, Lynskey ML, Allen JAM, Hoang S, Watkins SC, Pickett HA, O'Sullivan RJ.RRID:AB_2155627 TRF2,Novus,Cat# NB110-57130; RRID:AB_844199 BLM,Jan Karlseder,N/A MSH6,Cell Signaling Technology,Cat# 5424; RRID:AB_10695802 MSH3,Novus,Cat# NBP1-95114;RRID:AB_11028618 γ-TUB,Sigma-Aldrich,Cat# T6557; RRID:AB_477584 FLAG,Sigma-Aldrich,Cat#

(8) Identification of ARGLU1 as a potential therapeutic target for gastric cancer based on genome-wide functional screening dataEBioMedicineJuly 1, 2021Li F, Li J, Yu J, Pan T, Yu B, Sang Q, Dai W, Hou J, Yan C, Zang M, et al.1:200, CST, CAT# 2017), MSH3 (dilution 1:200, Abcam, CAT# ab275928) and MSH6 (dilution 1:200, CST, CAT# 5424) overnight at 4 °C. Biotinylated goat anti-mouse immunoglobulin G was used as a secondary antibody.

(9) Novel Thiosemicarbazones Sensitize Pediatric Solid Tumor Cell-Types to Conventional Chemotherapeutics through Multiple Molecular MechanismsCancersDecember 15, 2020Paukovcekova S, Skoda J, Neradil J, Mikulenkova E, Chlapek P, Sterba J, Richardson DR, Veselska R.Mono/Rb Mono/Rb Mono/Rb Mono/Rb Mono/Mo Mono/Mo Mono/Rb Mono/Rb Mono/Rb Mono/Rb C67E7 D9E D5H5 14C10 4C9C7 D24B5 D60G2 D10G9 4691S 4060S 12282S 2118S 51234M 3515S 2017S 5424S 9485 12286 CST CST CST CST Bioss CST CST CST CST CST 1:2000 1:2000 1:1000 1:10,000 1:1000 1:1000 1:2500 1:2500 1:2000 1:1000 Secondary

(10) Poly(ADP-ribose) Glycohydrolase Inhibition Sequesters NAD⁺ to Potentiate the Metabolic Lethality of Alkylating Chemotherapy in IDH-Mutant Tumor CellsCancer discoveryNovember 1, 2020Nagashima H, Lee CK, Tateishi K, Higuchi F, Subramanian M, Rafferty S, Melamed L, Miller JJ, Wakimoto H, Cahill DP.(Cell Signaling Technology, #2775), MGMT(Cell Signaling Technology, #2739), MSH6 (Cell Signaling Technology, #5424), PARG (Cell Signaling Technology, #66564), PARP (Cell Signaling Technology, #9542), Phospho-Histone

(11) CAPRI enables comparison of evolutionarily conserved RNA interacting regionsNature communicationsJune 18, 2019Panhale A, Richter FM, Ramírez F, Shvedunova M, Manke T, Mittler G, Akhtar A.(Invitrogen 459200), TOMM20 (Santa Cruz sc-11415), XRCC5 (Invitrogen MA5–15873), MSH6 (Cell Signalling 5424P), GAPDH (Bethyl A300-641A), HUR (3A2) (Santa Cruz 5261) and FLAG HRP (Sigma A8592). All antibodies were

(12) HIV-1 Vpr Reprograms CLR4^DCAF1 E3 Ubiquitin Ligase to Antagonize Exonuclease 1-Mediated Restriction of HIV-1 InfectionMBioOctober 23, 2018Yan J, Shun MC, Hao C, Zhang Y, Qian J, Hrecka K, DeLucia M, Monnie C, Ahn J, Skowronski J.α-Fen1 (A300-255A-T), and α-HLTF (A300-230A) from Bethyl Laboratories Inc.; α-Ape1 (4128), α-MSH6 (5424), α-MLH1 (3515), α-ERCC1 (12345), and α-CHK1 Ser345P (2341P) from Cell Signaling; α-RNAseH2b (sc-84590),

(13) Rare Stochastic Expression of O6-Methylguanine- DNA Methyltransferase (MGMT) in MGMT-Negative Melanoma Cells Determines Immediate Emergence of Drug-Resistant Populations upon Treatment with Temozolomide In Vitro and In VivoCancersSeptember 28, 2018Chen TC, Chan N, Minea RO, Hartman H, Hofman FM, Schönthal AH.a monoclonal antibody (ab39253) from Abcam (Cambridge, MA, USA). Anti-MSH2 (#2017) and anti-MSH6 (#5424) antibodies were from Cell Signaling. Human TRA-1-85 antibody (MAB3195) was from R&D Systems (Minneapolis,

(14) LC‑MS/MS metabolome analysis detects the changes in the lipid metabolic profiles of dMMR and pMMR cellsOncology ReportsJune 20, 2018Wen Peng et al.analyzed by probing the membranes with MLH1 (cat. no. 4256s), MSH2 (cat. no. 2017s), MLH6 (cat. no. 5424s) and PMS2 (cat. no. 2455s) antibodies (dilution 1:1,000; all were obtained from Cell Signaling Technology;

(15) Synuclein gamma expression enhances radiation resistance of breast cancer cellsOncotargetJune 8, 2018Tian L, Zhao Y, Truong MJ, Lagadec C, Bourette RP.

(16) Drug-Repositioning Screens Identify Triamterene as a Selective Drug for the Treatment of DNA Mismatch Repair Deficient CellsClinical Cancer ResearchJune 1, 2017Delphine Guillotin, Philip Austin, Rumena Begum, Marta O. Freitas, Ashirwad Merve, Tim Brend, Susan Short, Silvia Marino, Sarah A. Martinelectrophoresed on Novex precast gels (Invitrogen) and immunoblotted using the following antibodies: anti-MSH6 (#5424), anti-MSH2 (#2017), anti-MLH1 (#4256), anti-thymidylate synthase (#9045), β-Actin (#4970), purchased

(17) High-performance computing in accelerating structure design and analysisNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated EquipmentMarch 1, 2006Zenghai Li, Nathan Folwell, Lixin Ge, Adam Guetz, Valentin Ivanov, Marc Kowalski, Lie-Quan Lee, Cho-Kuen Ng, Greg Schussman, Lukas Stingelin, et al.eighteen vacuum chamber modes having medium frequency [1] ZDR report for the Next Linear Collider, LBNLPUB-5424, SLAC Report 474, UCRL-ID124161, 1996. [2] MAFIA User’s Guide, CST GmbH, Darmstadt, Germany. [3] HFSS:

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MSH6 (D60G2) XP ® Rabbit mAb

MSH6 (D60G2) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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MSH6 (D60G2) XP ® Rabbit mAb from Cell Signaling Technology

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