LIMK2 (8C11) Rabbit mAb 3845S from Cell Signaling Technology

Product Specs
ItemLIMK2 (8C11) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number3845S
Quantity100 µl
ApplicationsW
ReactivityH, Mk
TargetLIMK2
IsotypeIgG
HostRabbit
ClonalityMonoclonal
NCBI Full Gene NameLIM domain kinase 2
Clone8C11
Molecular Weight70
Research AreaCytoskeletal Signaling

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
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Website: http://www.cellsignal.com/

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(1) Discovery and Development of a Potent LIMK2 Isoform-Specific DegraderACS Chem BiolMay 15, 2026Kamal Rayees Abdul Azeez, Hayuningbudi Saraswati, Thorsten Mosler, Thomas Hanke, Hung Ho-Xuan, Noah Neder, Saran Aswathaman Sivashanmugam, Marcel Heinz, Martin-Peter Schwalm, Giulio Giuliani, et al.dilution), LIMK1 (catalog no. 3842, Cell Signaling Technology, 1:1000 dilution), LIMK2 (catalog no. 3845, 1:500 dilution), phospho-Cofilin (catalog no. 3313, Cell Signaling Technology, 1:1000 dilution), Cofilin

(2) Covalent Targeting Leads to the Development of a LIMK1 Isoform-Selective InhibitorJ Med ChemJuly 24, 2025Sebastian Mandel, Thomas Hanke, Niall Prendiville, María Baena-Nuevo, Lena Marie Berger, Frederic Farges, Martin Peter Schwalm, Benedict-Tilman Berger, Andreas Kraemer, Lewis Elson, et al.Cell Signaling Technology: GADPH (Cat. No. 2118, dilution 1:1000); LIMK1 (Cat. No. 3842, dilution 1:1000); LIMK2 (Cat. No. 3845, dilution 1:500); p-cofilin (Cat. No. 3313, dilution 1:1000); cofilin (Cat. No. 5175, dilution 1:1000). Multiplex

(3) Repurposing of the RIPK1-Selective Benzo[1,4]oxazepin-4-one Scaffold for the Development of a Type III LIMK1/2 InhibitorACS Chemical BiologyMay 16, 2025Sebastian Mandel, Thomas Hanke, Sebastian Mathea, Deep Chatterjee, Hayuningbudi Saraswati, Benedict-Tilman Berger, Martin Peter Schwalm, Satoshi Yamamoto, Michiko Tawada, Terufumi Takagi, et al.dilution), LIMK1 (catalog no. 3842, Cell Signaling Technology, 1:1000 dilution), LIMK2 (catalog no. 3845, 1:500 dilution), p-cofilin (catalog no. 3313, Cell Signaling Technology, 1:1000 dilution), cofilin

(4) Discovery of electrophilic degraders that exploit SNAr chemistrybioRxivSeptember 27, 2024Zhe Zhuang, Woong Sub Byun, Zuzanna Kozicka, Brendan G. Dwyer, Katherine A. Donovan, Zixuan Jiang, Hannah M. Jones, Dinah M. Abeja, Meredith N. Nix, Jianing Zhong, et al.Hercules, CA, USA), Anti-PTK2B (cat.no. 67141-1-Ig; Proteintech, Rosemont, IL, USA), anti-LIMK2 (cat. no. 3845; Cell Signaling Technology), anti-ITK (cat. no. 2380; Cell Signaling Technology), anti-Aurora A (cat.

(5) TAZ is involved in breast cancer cell migration via regulating actin dynamicsFrontiers in OncologyMay 7, 2024Hong Seok Choi, Hyo-Ju Jang, Mathilde K. Kristensen, Tae-Hwan Kwon#3675, Cell signaling Technology), LIMK1 (1:1,000, #3842, Cell signaling Technology), LIMK2 (1:1,000, #3845, Cell signaling Technology), phospho-LIMK (1:1,000, #3841, Cell signaling Technology), cofilin (1:1,000,

(6) Protocatechuic acid prevents isoproterenol-induced heart failure in mice by downregulating kynurenine-3-monooxygenaseJournal of cellular and molecular medicineAugust 1, 2023Bai L, Han X, Kee HJ, He X, Kim SH, Jeon MJ, Zhou H, Jeong SM, Kee SJ, Jeong MH.Anti‐Col 3 (ab7778) antibody was purchased from Abcam. Anti‐Smad3 (9523T, lot no. 7) and anti‐Smad4 (3845T, lot no. 3) were purchased from Cell Signaling. 2.2 Establishment of an animal model of heart failure A

(7) Cytoplasmic Clusterin Suppresses Lung Cancer Metastasis by Inhibiting the ROCK1-ERK AxisCancersMay 17, 2022Huang S, Li X, Gu W, Li X, Zhao J, Wu J, Cai J, Feng X, Tao T.antibody (1:1000; 3671T, Cell Signaling Technology, Danvers, MA, USA), anti-LIMK2 antibody (1:1000; 3845, Cell Signaling Technology, Danvers, MA, USA), anti-p-ERK1/2 (T202/Y204) antibody (1:1000; 4370, Cell Signaling Technology

(8) Fetal Zone Steroids Show Discrete Effects on Hyperoxia-Induced Attenuation of Migration in Cultured Oligodendrocyte Progenitor CellsOxidative Medicine and Cellular LongevityMay 9, 2022Donna E. Sunny, Elisabeth L. Krüger, Elke Hammer, Uwe Völker, Matthias Heckmann,1 : 1000 Phospho-cofilin (Ser3) (77G2) Rabbit mAb 3313,Cell Signaling Technology,1 : 1000 LIMK2 (8C11) rabbit mAb 3845,Cell Signaling Technology,1 : 1000 TESK1 (D49D4) rabbit mAb 4655,Cell Signaling Technology,1 : 1000 ROCK1 (C8F7) rabbit mAb

(9) Cepharanthine sensitizes human triple negative breast cancer cells to chemotherapeutic agent epirubicin via inducing cofilin oxidation-mediated mitochondrial fission and apoptosisActa pharmacologica SinicaJanuary 1, 2022Shen LW, Jiang XX, Li ZQ, Li J, Wang M, Jia GF, Ding X, Lei L, Gong QH, Gao N.(8570), ATG5 (12994), p62 (5114 S), phospho-Cofilin (3313), phospho-LIMK1/2 (3841), LIMK1 (3842), LIMK2 (3845), GAPDH (2118) were purchased from Cell Signaling Technology (Boston, MA, USA). VDAC1 (ab14734) was

(10) 0.5‑Gy X‑ray irradiation induces reorganization of cytoskeleton and differentiation of osteoblastsMolecular Medicine ReportsMarch 17, 2021Qun Huang, Hao Chai, Shendong Wang, Yongming Sun, Wei XuInc.; dilution 1:2,000), rabbit anti-phosphorylated (phospho)-LIM domain kinase 2 (LIMK2; cat. no. 3845, Cell Signaling Technology, Inc.; dilution 1:2,000), rabbit anti-phospho-Cofilin (cat. no. 3311; Cell Signaling Technology

(11) Potential Antimetastatic Effect of Timosaponin AIII against Human Osteosarcoma Cells through Regulating the Integrin/FAK/Cofilin AxisPharmaceuticals (Basel, Switzerland)March 14, 2021Hsieh YH, Hsu WH, Yang SF, Liu CJ, Lu KH, Wang PH, Lin RC.total-cofilin (5175T), TESK1 (4655T), SSH1 (13578T), phospho-LIMK1-Thr508/LIMK2-Thr505 (3841S), total-LIMK1/2 (3845T), and glyceraldehyde-3-phosphate dehydrogenase (GAPDH, 2118S) were purchased from Cell Signaling Technology

(12) Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24Nature communicationsJanuary 21, 2021Cao X, Khitun A, Luo Y, Na Z, Phoodokmai T, Sappakhaw K, Olatunji E, Uttamapinant C, Slavoff SA.anti-p-LIMK2(T505) (1:500, Cell Signaling Technology, 3841); anti-LIMK2 (1:500, Cell Signaling Technology, 3845); anti-p-EGFR(Y1068) (1:1000, Abcam, ab40815); anti-EGFR (1:1000, Abcam, ab52894); anti-RPL36 (1:1000,

(13) Low-dose X-ray irradiation induces morphological changes and cytoskeleton reorganization in osteoblastsExperimental and therapeutic medicineDecember 1, 2020Huang Q, Zhou Z, Yan F, Dong Q, Wang L, Sha W, Xu Q, Zhu X, Zhao L.(cat. no. 4035; dilution 1:2,000; Cell Signaling Technology, Inc.), rabbit anti-phospho-LIMK2 (cat. no. 3845; dilution 1:2,000; Cell Signaling Technology, Inc.), rabbit anti-phospho-cofilin (cat. no. 3311; dilution

(14) Filtering two-element waveguide antenna array based on solely resonatorsAEU - International Journal of Electronics and CommunicationsJuly 1, 2020Rashad H. Mahmud, Halgurd N. Awl, Yadgar I. Abdulkarim, Muharrem Karaaslan, Michael J. Lancasteron all-resonator structures," IEEE Transactions on Microwave Theory and Techniques, vol. 61, pp. 3838-3845, 2013. C. M. Studio, "CST Computer Simulation Technology AG, 2019," ed, 2019. T. F. Skaik, M. Lancaster,

(15) TGF-β1-mediated repression of SLC7A11 drives vulnerability to GPX4 inhibition in hepatocellular carcinoma cellsCell death & diseaseMay 29, 2020Kim DH, Kim WD, Kim SK, Moon DH, Lee SJ.phospho-Smad2 (Ser 465/467; #8828), phospho-Smad3 (Ser 423/425; #9520), Smad2/Smad3 (#5678), Smad4 (#3845), E-cadherin (#3195), phospho-ERK (#4370), ERK (#4696), phospho-AKT (#4060), AKT (#2920), and phospho-p70S6-kinase1

(16) Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma InvasionCancer researchJanuary 1, 2020Chen J, Ananthanarayanan B, Springer KS, Wolf KJ, Sheyman SM, Tran VD, Kumar S.primary antibody (rabbit LIMK1 (1:1000, Cell Signaling 3842S); rabbit LIMK2 (1:1000, Cell Signaling 3845S); rabbit pCofilin (1:1000, Cell Signaling 3313S); rabbit Cofilin (1:1000, Cell Signaling 5175S); and

(17) Degree of Hearing Loss Affects Bilateral Hearing Aid Benefits in Ecologically Relevant Laboratory ConditionsJournal of Speech, Language, and Hearing ResearchOctober 25, 2019Todd A. Ricketts, Erin M. Picou, James Shehorn, Andrew B. DittbernerSpeech Recognition; LE = Listening Effort. Ricketts et al.: Bilateral Benefits With Hearing Aids 3845 Overall, these data demonstrated that, even under ecologically relevant conditions, which may be

(18) The CK2 inhibitor CX4945 reverses cisplatin resistance in the A549/DDP human lung adenocarcinoma cell lineOncology lettersOctober 1, 2019Jin C, Song P, Pang J.no. ab124941; 1:1,000; Abcam), c‑Myc (cat. no. 9402; 1:500; Cell Signaling ONCOLOGY LETTERS 18: 3845-3856, 2019 Technology, Inc.), caspase‑3 (cat. no. sc‑271759; 1:500; Santa Cruz Biotechnology, Inc.),

(19) Microbial degradation of Cold Lake Blend and Western Canadian select dilbits by freshwater enrichmentsJournal of Hazardous MaterialsJune 1, 2018Ruta S. Deshpande, Devi Sundaravadivelu, Stephen Techtmann, Robyn N. Conmy, Jorge W. Santo Domingo, Pablo Campo°C cSt 230.7 199.7 Total Alkanes μg/g of dilbit 3100 4000 Total PAHs μg/g of dilbit 3540 3845 * Note: Dilbit characterization was done by Maxxam Analytical International Corp. (Petroleum Technology

(20) Rho A Regulates Epidermal Growth Factor-Induced Human Osteosarcoma MG63 Cell MigrationInternational journal of molecular sciencesMay 11, 2018Wang J, Zhang L, Qu R, Zhang L, Huang W.#ab203273); rabbit polyclonal antibodies against LIMK2 (Cell Signaling Technology, Danvers, MA, USA, #3845) and phosphorylated-LIMK2 (p-Limk2; Sigma, St Louis, MO, USA, #SAB4300104); mouse monoclonal antibodies

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LIMK2 (8C11) Rabbit mAb

LIMK2 (8C11) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (25)

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LIMK2 (8C11) Rabbit mAb from Cell Signaling Technology

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