XIAP (3B6) Rabbit mAb 2045S from Cell Signaling Technology

Product Specs
ItemXIAP (3B6) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number2045S
Quantity100 µl
ApplicationsW
ReactivityH, Mk
TargetXIAP
HostRabbit
NCBI Gene AliasesAPI3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3
ClonalityMonoclonal
NCBI Full Gene NameX-linked inhibitor of apoptosis
Research AreaApoptosis
IsotypeIgG
Clone3B6
Molecular Weight53

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Epstein-Barr Virus Latent Membrane Protein 1 Suppresses Ferroptosis via Pentose Phosphate Pathway and Glutathione MetabolismbioRxivMarch 13, 2026Eric M. Burton, Bidisha Mitra, Rui Guo, John M. Asara, Benjamin E. Gewurz(Abcam, EPR28633–53), PFKFB4 (Proteintech, 29902–1-AP), EPR28633–53)XIAP (Cell Signaling Technology, # 2045S), SLC7A11/xCT (Cell Signaling Technology, 12691S) CIAP1 (Proteintech, 66626–1-IG), CIAP2 (Cell Signaling Technology

(2) Loss of ADAM15 prevents necroptosis induction by partial RIPK1 degradation due to enhanced TNF-R1 surface expression and basal caspase-8 activationCell Commun SignalDecember 4, 2025S. Braun, K. Knackfuß, T. Ziesmann, L. Mlinzk, A. Goerg, J. Frankenheim, A. Walter, W. Schneider-Brachert, U. Distler, J. Fritschfull-length caspase-3 (#9668S), MLKL (#14993S), RIPK1 (#3493S), RIPK3 (#10188S), MMP9 (#13,667), xIAP (#2045S), TNF-R1 (#3736S), DR4 (#42533S), DR5 (#8074S), Cathepsin D (#69,854), CoxIV (#69,854), ERp72 (#5033S),

(3) Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axisFront ImmunolFebruary 12, 2025Daciana C. Dumut, Marian Hajduch, Amanda M. Zacharias, Qingling Duan, Ivo Frydrych, Zuzana Rozankova, Miroslav Popper, Dusan Garic, Radu Alexandru Paun, Amanda Centorame, et al.(#405306, BioLegend, 1:10000), ii) with primary antibodies anti-PARP (#9542S, 1:1000), and iii) anti-XIAP (#2045S, 1:1000) antibodies (Cell Signaling Technologies) paired with secondary HRP antibody (#31458, Invitrogen,

(4) CDK9 inhibition constrains multiple oncogenic transcriptional and epigenetic pathways in prostate cancerBritish Journal of CancerOctober 5, 2024Razia Rahman, Muhammed H. Rahaman, Adrienne R. Hanson, Nicholas Choo, Jianling Xie, Scott L. Townley, Raj Shrestha, Ramin Hassankhani, Saiful Islam, Susanne Ramm, et al.(15071S; Cell Signaling Technology; 1:500); MCL-1 (94296S, Cell Signaling Technology; 1:500); XIAP (2045S; Cell Signaling Technology; 1:500); AR (ab108341, Abcam; 1:1000); pSer81-AR (07-1375, Merck; 1:1000);

(5) The Synergistic Anti-Tumor Activity of EZH2 Inhibitor SHR2554 and HDAC Inhibitor Chidamide through ORC1 Reduction of DNA Replication Process in Diffuse Large B Cell LymphomaCancers (Basel)August 24, 2021Xing Wang et al.and stored at 4 °C. Antibodies against Caspase-3 (#9662S), Mcl-1 (#5453S), Bcl-xl (#2764S), XIAP (#2045S), CDK2 (#2546S), CDK4 (#12790S), CDK6(#13331S), H3K27me3(#9733T), H3K27ac(#9649S), H3(#4499S), EZH2(#5246S),

(6) FAM188B Expression Is Critical for Cell Growth via FOXM1 Regulation in Lung CancerBiomedicinesOctober 31, 2020Choi YE, Madhi H, Kim H, Lee JS, Kim MH, Kim YN, Goh SH.Santa Cruz Biotechnology, Santa Cruz, CA, USA); and c-Myc (5605S), cyclin D1 (2978S), phosphor-BAD (4366S), XIAP (2045S), Survivin (2808S), Aurora kinase B (3094S), cyclin B1 (4138S) and PARP (9542S) (Cell Signaling Technology,

(7) The LQB-223 Compound Modulates Antiapoptotic Proteins and Impairs Breast Cancer Cell Growth and MigrationInternational journal of molecular sciencesOctober 12, 2019Lemos LGT, Longo GMDC, Mendonça BDS, Robaina MC, Brum MCM, Cirilo CA, Gimba ERP, Costa PRR, Buarque CD, Nestal de Moraes G, et al.the primary antibodies diluted in TBS/BSA 2% against FOXM1 (1:500, sc-502, Santa Cruz), XIAP (1:1000, 2045S, Cell Signaling), c-IAP 1 (1:2000, AF8181, R&D Systems), survivin (1:1000, 2808S, Cell Signaling), Mcl-1

(8) A Novel Naphthyridine Derivative, 3u, Induces Necroptosis at Low Concentrations and Apoptosis at High Concentrations in Human Melanoma A375 CellsInternational journal of molecular sciencesSeptember 29, 2018Kong Q, Lv J, Yan S, Chang KJ, Wang G.

(9) Calmodulin antagonist enhances DR5-mediated apoptotic signaling in TRA-8 resistant triple negative breast cancer cellsJournal of cellular biochemistryJuly 1, 2018Fancy RM, Kim H, Napier T, Buchsbaum DJ, Zinn KR, Song Y.Cat.4060S, Lot#19), XIAP (Cell Signaling Technologies, specificity: XIAP (3B6) (53 kDa), source: rabbit, Cat.2045S, Lot#3), and cIAP-1 (Cell Signaling Technologies specificity: cIAP-1(62 kDa), source: rabbit, Cat.4952S,

(10) Hypertonicity-enforced BCL-2 addiction unleashes the cytotoxic potential of death receptorsOncogeneJuly 1, 2018Sirtl S, Knoll G, Trinh DT, Lang I, Siegmund D, Gross S, Schuler-Thurner B, Neubert P, Jantsch J, Wajant H, et al.

(11) Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytesMolecular metabolismJanuary 1, 2018Pisani DF, Barquissau V, Chambard JC, Beuzelin D, Ghandour RA, Giroud M, Mairal A, Pagnotta S, Cinti S, Langin D, et al.

(12) Interferon-γ and Smac mimetics synergize to induce apoptosis of lung cancer cells in a TNFα-independent mannerCancer cell internationalJanuary 1, 2018Hao Q, Tang H.

(13) Difference in intracellular temperature rise between matured and precursor brown adipocytes in response to uncoupler and β-adrenergic agonist stimuliScientific ReportsDecember 1, 2017Toshikazu Tsuji, Kumiko Ikado, Hideki Koizumi, Seiichi Uchiyama, Kazuaki Kajimoto

(14) KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasisNature medicineOctober 1, 2017Murgai M, Ju W, Eason M, Kline J, Beury DW, Kaczanowska S, Miettinen MM, Kruhlak M, Lei H, Shern JF, et al.

(15) Downregulation of X-linked inhibitor of apoptosis protein by '7-Benzylidenenaltrexone maleate' sensitizes pancreatic cancer cells to TRAIL-induced apoptosisOncotargetSeptember 22, 2017Kim SY, Park S, Yoo S, Rho JK, Jun ES, Chang S, Kim KK, Kim SC, Kim I.

(16) Platinum pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via DUB inhibition-dependent caspase activation and Bcr-Abl downregulationCell death & diseaseJuly 6, 2017Lan X, Zhao C, Chen X, Zhang P, Zang D, Wu J, Chen J, Long H, Yang L, Huang H, et al.

(17) iTRAQ-Based Quantitative Proteomic Analysis of the Inhibitory Effects of Polysaccharides from Viscum coloratum (Kom.) Nakai on HepG2 CellsScientific ReportsJuly 4, 2017Yangyang Chai, Min Zhao

(18) Paradoxical induction of growth arrest and apoptosis by EGF via the up-regulation of PTEN by activating Redox factor-1/Egr-1 in human lung cancer cellsOncotargetJanuary 17, 2017Ryu JW, Choe SS, Ryu SH, Park EY, Lee BW, Kim TK, Ha CH, Lee SW.

(19) Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agentsCell death & diseaseSeptember 8, 2016Klingbeil O, Lesche R, Gelato KA, Haendler B, Lejeune P.

(20) Let-7i-5p represses brite adipocyte function in mice and humansScientific ReportsSeptember 1, 2016Maude Giroud et al.

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XIAP (3B6) Rabbit mAb

XIAP (3B6) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (26)

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XIAP (3B6) Rabbit mAb from Cell Signaling Technology

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