c-Rel Antibody 4727S from Cell Signaling Technology

Product Specs
Itemc-Rel Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number4727S
Quantity100 µl
ApplicationsW, IP
ReactivityH
TargetRel
Molecular Weight78
HostRabbit
NCBI Full Gene NameREL proto-oncogene, NF-kB subunit
NCBI Gene AliasesC-Rel, HIVEN86A, IMD92
ClonalityPolyclonal
Research AreaImmunology and Inflammation

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Dissecting the role of imiquimod and isostearic acid in Aldara-induced psoriasis mouse modelJID InnovationsMay 1, 2026Angela Rose Liu, Sophia T. Gavalas, Ananya Vadlakonda, Nandini Sarkar, Parameswaran RamakrishnanPatterson Veterinary Supply. Antibodies against the following proteins were used in this study: c-Rel (4727, Cell Signaling Technology), p65 (C20, Santa Cruz Biotechnology), p50 (D4P4D, Cell Signaling Technology),

(2) Heterozygous NFKB1 variant causes inflammatory dysregulation shaped by broader genetic context in common variable immunodeficiencyJCI InsightMarch 23, 2026Kevin M. Hayes, Kai Boldt, Peter J. Schnorr, Pushpinder Bawa, Miranda L. Abyazi, Matthew S. Ware, Gavin Gyimesi, Marianne James, Huaibin M. Ko, Charlotte Cunningham-Rundles, et al.p105/p50 (Cell Signaling Tech, 3035S), RelB (Cell Signaling Tech, 4954S), C-Rel (Cell Signaling Tech, 4727S), p100/p52 (Cell Signaling Tech, 4882S), and p65 (Cell Signaling Tech, 3035S). The next day, membranes

(3) NF-κB is a central regulator of hypoxia-induced gene expressionEMBO ReportsNovember 26, 2025Dilem Shakir, Michael Batie, Chun-Sui Kwok, Simon J Cook, Niall S Kenneth, Sonia Rochatarget),,Sequence RelA,IDT,GCCCUAUCCCUUUACGUCA RelB,IDT,GGAUUUGCCGAAUUAACAA cRel,IDT,ACAGCUGAAUGAUAUUGAA Control,IDT,CAGUCGCGUUUGCGACUGG Antibodies,Antibodies,Antibodies RelA,Santa Cruz,sc-8008 RelB,Cell Signalling,10544 cRel,Cell Signalling,4727 HIF-1α,BD Biosciences,610958 β-Actin,Proteintech,66009-1-lg IDH1,Proteintech,12332-1-AP SOD1,Santa Cruz

(4) Insight into prostate cancer osteolytic metastasis by RelB coordination of IL‐8 and S100A4Clinical and Translational MedicineOctober 16, 2024Wenbo Sun, Kenny Xu, Xiao Li, Peipei Qian, Fan Xu, Yanyan Zhang, Xiumei Wang, Zhi Xu, Jiaji Ding, Xinyu Xu, et al.provided by Cell Signaling Technology, including AR (54653), Ikkα (2682), RelA (9609), RelB (4954), c‐Rel (4727), p105/p50 (3035), p100/p52 (4882), IL‐8 (9447), Sp1 (5931), NFATc1 (8032), Snail 1 (3879), Twist 1

(5) Single cell and bulk RNA expression analyses identify enhanced hexosamine biosynthetic pathway and O-GlcNAcylation in acute myeloid leukemia blasts and stem cellsFrontiers in immunologyJanuary 1, 2024Schauner R, Cress J, Hong C, Wald D, Ramakrishnan P.sc-9104), p65 (Santa Cruz, Cat# sc-372), p50 (Cell Signaling, Cat# 13586S), c-Rel (Cell signaling, Cat# 4727S), and Lamin A/C (Santa Cruz, Cat# sc-20681). 2.4 Quantitative real-time PCR OCI-AML3 cells (5 x 105

(6) Characterization of target gene regulation by the two Epstein-Barr virus oncogene LMP1 domains essential for B-cell transformationmBioNovember 27, 2023Bidisha Mitra, Nina Rose Beri, Rui Guo, Eric M. Burton, Laura A. Murray-Nerger, Benjamin E. GewurzRelA (#8242, rabbit mAb), phospho-RelA (Ser536) (3033, rabbit mAb), RelB (#4922, rabbit mAb), cRel (#4727, rabbit mAb), IκBα (#9247, mouse mAb), IRF4 (#4964, rabbit mAb), BATF (#8638, rabbit mAb), TAK1 (#4505,

(7) Characterization of Target Gene Regulation by the Two Epstein-Barr Virus Oncogene LMP1 Domains Essential for B-cell TransformationbioRxivApril 13, 2023Bidisha Mitra, Rui Guo, Eric M. Burton, Laura A. Murray-Nerger, Benjamin E. GewurzRelA (#8242, Rabbit mAb), phospho-RelA (Ser536) (3033, Rabbit mAb), RelB (#4922, Rabbit mAb), cRel (#4727, Rabbit mAb), IκBα (#9247, Mouse mAb), IRF4 (#4964, Rabbit mAb), TAK1 (#4505, Rabbit mAb), V5 (#13202,

(8) EPO regulates neuronal differentiation of adult human neural-crest derived stem cells in a sex-specific mannerBMC neuroscienceMarch 6, 2023Niemann T, Greiner JFW, Kaltschmidt C, Kaltschmidt B.Rockland, PA. USA), RELB (rabbit, D7D7W, 1:500, Cell Signaling Technology, Danvers, USA), c-Rel (rabbit, 4727, 1:500, Cell Signaling Technology), vGlut-II (rabbit, 07-1402-I, 1:300, Merck Millipore, Burlington,

(9) Inhibition of c-Rel expression in myeloid and lymphoid cells with distearoyl -phosphatidylserine (DSPS) liposomal nanoparticles encapsulating therapeutic siRNAPLOS ONEDecember 15, 2022Christian Bressy, Ali Zemani, Shreya Goyal, Davit Jishkariani, Chin Nien Lee, Youhai H. Chenanti-c-Rel antibody (Santa cruz; G-7; sc-365720) or human polyclonal anti-c-Rel antibody (Cell signaling; #4727) respectively, in 0.1% tween-20 TBS buffer containing 5% non-fat milk at 4°C overnight. The membrane

(10) Loss of LKB1-NUAK1 signalling enhances NF-κB activity in a spheroid model of high-grade serous ovarian cancerScientific ReportsDecember 1, 2022Adrian Buensuceso, Jamie Lee Fritz, Olga Collins, Yudith Ramos Valdés, Matthew J. Borrelli, Gabriel E. DiMattia, Trevor G. Shepherdagainst p-RelA-S536 (#3033; 1:1000), RelA (#8242; 1:1000), RelB (#4922, 1:2000; IHC: #10544), c-Rel (#4727; 1:1000), NF-κB2 (#3017; 1:1000), LKB1 (#3050; 1:1000), and NUAK1 (#4458; 1:1000) were purchased from

(11) Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3-Lgr4 axisThe EMBO journalJuly 4, 2022Wizenty J, Müllerke S, Kolesnichenko M, Heuberger J, Lin M, Fischer AS, Mollenkopf HJ, Berger H, Tacke F, Sigal M.sc‐8,414 X), RelB D‐4 (Santa Cruz, sc‐48,366 X), p52 (Millipore, 06–413), and cRel (Cell Signaling, #4727). Single‐molecule RNA ISH Tissue sections cut at 5 μm thickness were processed for RNA in situ detection

(12) PELI1 promotes radiotherapy sensitivity by inhibiting noncanonical NF-κB in esophageal squamous cancerMolecular oncologyMarch 1, 2022Dai D, Zhou H, Yin L, Ye F, Yuan X, You T, Zhao X, Long W, Wang D, He X, et al.(Ser15) (9284), anti‐ATM (2873), anti‐Phospho‐ATM (Ser1981) (13050), anti‐NF‐κB1 p105 (4717), anti‐c‐Rel (4727), anti‐Phospho‐NF‐κB2 p100/p52 (Ser866/870) (4810), and anti‐Phospho‐RelB (Ser552) (D41B9) (5025) antibodies

(13) IKKα plays a major role in canonical NF-κB signalling in colorectal cellsThe Biochemical journalFebruary 11, 2022Prescott JA, Balmanno K, Mitchell JP, Okkenhaug H, Cook SJ.(T180/Y182) (CST #9211), anti-PARP (CST #9542), anti-FLAG (Sigma–Aldrich F-3165), anti-c-Rel (CST #4727), anti-β-actin (Sigma A5441), anti- β -tubulin (Abcam ab6046), anti-Lamin A/C (Santa-Cruz sc-7292),

(14) S100A4 Is Involved in Stimulatory Effects Elicited by the FGF2/FGFR1 Signaling Pathway in Triple-Negative Breast Cancer (TNBC) CellsInternational journal of molecular sciencesApril 29, 2021Santolla MF, Talia M, Maggiolini M.(1C4) (Novus, DBA, Milan, Italy), FGFR1 (#9740), p-FGFR1 (#3476), p-AKT (Ser473) (D9E), and c-Rel (#4727) (Cell Signaling Technology, Euroclone Milan, Italy); p-ERK1/2 (E-4), ERK2 (C-14), AKT/1/2/3 (H-136)

(15) NF-κB c-Rel Is Dispensable for the Development but Is Required for the Cytotoxic Function of NK CellsFrontiers in immunologyJanuary 1, 2021Vicioso Y, Wong DP, Roy NK, Das N, Zhang K, Ramakrishnan P, Parameswaran R.(sc-47724), prf1(sc-136994) purchased from Santa Cruz Biotechnology, mouse prf1 (3693s), human c-Rel (4727s) purchased from Cell Signaling, and alpha tubulin (cp06) purchased from Calbiochem. Mouse and Rabbit

(16) Targeting lysosomal cysteine protease cathepsin S reveals immunomodulatory therapeutic strategy for oxaliplatin-induced peripheral neuropathyTheranosticsJanuary 1, 2021Chen SJ, Chen LH, Yeh YM, Lin CK, Lin PC, Huang HW, Shen MR, Lin BW, Lee JC, Lee CC, et al.(BD Biosciences, #553079), STAT3 (BD, #50402), P-STAT3 (Cell signaling, #9145S), NFκB (Cell signaling, #4727S), OR5B3 (Abcam, #ab186624), OR5M3 (LSBio, #LS-C200406), and β-actin (GeneTex, #GTX109639). Horseradish-peroxidase-conjugated

(17) The c-Rel-c-Myc axis controls metabolism and proliferation of human T leukemia cellsMolecular ImmunologySeptember 1, 2020Xinyuan Li, George Luo, Ting Li, Honghong Sun, Wei Wang, Emily Eiler, Jason R. Goldsmith, Youhai H. Chenblocked with 5% milk in TBST and probed with the following primary antibodies, overnight at 4°C: c-Rel (#4727, rabbit polyclonal, 1:2000, Cell signaling), c-Myc(#9402, rabbit monoclonal, 1:1000, Cell Signaling),

(18) The NF-κB Pathway Promotes Tamoxifen Tolerance and Disease Recurrence in Estrogen Receptor-Positive Breast CancersMolecular cancer research : MCRJuly 1, 2020Kastrati I, Joosten SEP, Semina SE, Alejo LH, Brovkovych SD, Stender JD, Horlings HM, Kok M, Alarid ET, Greene GL, et al.Chemicals. TNFα was purchased from R&D Systems. The antibodies for ERα (8644), p52 (37359), c-Rel (4727), RelB (4922), and TBP (8515) were purchased from Cell Signaling. The antibodies for p65 (sc-372) and

(19) c-Rel gain in B cells drives germinal center reactions and autoantibody productionThe Journal of clinical investigationJune 1, 2020Kober-Hasslacher M, Oh-Strauß H, Kumar D, Soberon V, Diehl C, Lech M, Engleitner T, Katab E, Fernández-Sáiz V, Piontek G, et al.retrieval buffer (PerkinElmer). Slides were incubated for 1 hour with the following antibodies: c-Rel (4727, Cell Signaling Technology), Bcl6 (EP278, Cell Marque), CD20 (L26, PerkinElmer), Ki-67 (SP6, Cell Marque),

(20) Toxoplasma GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11PLoS pathogensMay 1, 2020Mukhopadhyay D, Arranz-Solís D, Saeij JPJ.MAPK (1:800 dilution, #4511, Cell Signaling Technology, MA, USA), rabbit anti cREL (1:500 dilution, #4727, Cell Signaling Technology, MA, USA) and mouse anti cREL (1:200 dilution, NBP2-37593, Novus Biologicals,

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c-Rel Antibody

c-Rel Antibody from Cell Signaling Technology

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Cell Signaling Technology

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c-Rel Antibody from Cell Signaling Technology

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