PP2A C Subunit (52F8) Rabbit mAb 2259S from Cell Signaling Technology

Product Specs
ItemPP2A C Subunit (52F8) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number2259S
Quantity100 µl
ApplicationsW, IP, IHC-P
ReactivityH, M, R, Mk, Dm
TargetPP2A C subunit
HostRabbit
NCBI Gene AliasesNEDLBA, PP2Ac, PP2CA, PP2Calpha, RP-C
ClonalityMonoclonal
NCBI Full Gene Nameprotein phosphatase 2 catalytic subunit alpha
Research AreaCell Cycle / Checkpoint Control
Clone52F8
Molecular Weight36, 38

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Interleukin-17A Orchestrates Lung Injury and Remodeling Through p53 and uPA System CrosstalkInternational Journal of Molecular SciencesFebruary 14, 2026Durgesh Nandini Das, Akarsha Balnadupete, Rashmi Shetty, Venkadesa Perumal Gopu, Rushil Sajjan, Yashodhar P. Bhandary, Amarnath S. Marudamuthu, Christian Oliver, Aarav Patel, Aryan Patel, et al.,Southern Biotech,#1340-01,1:1000, 15,Anti-FN Ab,Molecular Innovations,#ASMFBN,1:1000, 16,PNUTS,CST,14171,1:1000, 17,PP2Ac,CST,2259S,1:1000, 18,pATM,Millipore,05-740Sp,1:1000, 19,MDM2,Abcam,ab226939,1:1000, 20,ATM,Millipore,05513,1:1000, 21,Anti-αSMA

(2) MYC drives left-handed Z-DNA formation to shape gene expressionNature CommunicationsDecember 1, 2025Xinyi Wan, Haonan Fan, Zhuoning Li, Yixuan Du, Yu Liu, Weiwu Zeng, Zhongxing Sun, Juejia Shao, Junqi Jia, Yanjun Zhang, et al.anti-Histone H2B (Abcam, Cat. #ab177430); Rabbit monoclonal anti-PP2AC (Cell Signaling Technology, Cat. #2259); Mouse monoclonal anti-S9.6 antibody (Kerafast, Cat. #ENH001); Rabbit monoclonal anti-γ-Histone H2A.X

(3) RNA polymerase II subunit 5-mediating protein limits TLR4-induced innate immune activation in macrophages by inhibiting IKKβ/NF-κB signaling during sepsisCell Commun SignalJune 10, 2025Shu-Jie Pang, Tian-Yi Jiang, Nai-Guo Wang, Xiao-Wen Cui, Hui Wang, Yu-Fei Pan, Ning Yang, Li-Wei DongAB_331659), anti-PP2Aa (2041, RRID: AB_2168121), anti-PP2Ab (2290, RRID: AB_659890), and anti-PP2Ac (2259, RRID: AB_561239) were purchased from Cell Signaling Technology. Mouse IgG (sc-2025, RRID: AB_737182)

(4) Autophagosomes anchor an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signalingThe EMBO JournalApril 22, 2025Ashley Segura-Roman, Y Rose Citron, Myungsun Shin, Nicole Sindoni, Alex Maya-Romero, Simon Rapp, Claire Goul, Joseph D Mancias, Roberto Zoncu(#2041), HOP (#5670), eEF1A (#2551), CACYBP (#3354), HSP90 (#4874), CCT2 (#3561), PSMA2 (#11864), PP2AC (#2259), GPI (#57893), GSK3β (#12456), Synapsin (#4297), Oct4 (#27505) from Cell Signaling Technologies. SQSTM1/p62

(5) Sephin1 suppresses ER stress-induced cell death by inhibiting the formation of PP2A holoenzymeCell Death DisFebruary 19, 2025Satoshi Gojo, Daisuke Kami, Arata Sano, Fumiya Teruyama, Takehiro Ogata, Satoaki Matobasubunit B (100C1, Cell Signaling Technology Inc.), PP2ABδ (116609, Gene Tex, Irvine, USA), PP2ACα/β (2259, Cell Signaling Technology Inc.), or AMPK (2603, Cell Signaling Technology, Inc.) were mixed with cell

(6) Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation, and cell cycle progressionbioRxivNovember 12, 2024Nathaniel Shannon, Cory Raymond, Chloe Palmer, David Seward, Brian CunniffOrigene #CF11035) MKP3/DUSP6 (1:1000, Invitrogen #MA5-35048), PP2AC (1:1000, Cell Signaling Technology #2259), GAPDH (1:3000, Invitrogen #MA5-15738), Cyclin D1 (1:1000, Cell Signaling Technology #2978), Cyclin

(7) m(6)A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1Cell metabolismOctober 1, 2024Xiao L, De Jesus DF, Ju CW, Wei JB, Hu J, DiStefano-Forti A, Tsuji T, Cero C, Männistö V, Manninen SM, et al.AB_2253290 PP2A-B,Cell Signaling Technology,2290; RRID: AB_659890 PP2A-C,Cell Signaling Technology,2259; RRID: AB_561239 PHLPP-1,Proteintech,22789-I-AP; RRID: AB_2750897 PHLPP-2 (PHLPPL),Proteintech,25244-I-AP;

(8) Ficolin 3 promotes ferroptosis in HCC by downregulating IR/SREBP axis-mediated MUFA synthesisJournal of Experimental & Clinical Cancer ResearchMay 3, 2024Yanmei Yuan, Junting Xu, Quanxin Jiang, Chuanxin Yang, Ning Wang, Xiaolong Liu, Hai-long Piao, Sijia Lu, Xianjing Zhang, Liu Han, et al.1:1000, #9188, CST; protein phosphatase 2 (PP2A) A subunit, 1:1000, #2041, CST; PP2A C subunit, 1:1000, #2259, CST; HA, 1:2000, M2003, Abmart; β-Tubulin, 1:3000, AP0064, Bioworld; GAPDH, 1:3000, A19056, ABclonal;

(9) A novel GSK3β inhibitor 5n attenuates acute kidney injuryHeliyonApril 30, 2024Cai YT, Li Z, Wang YY, Li C, Ma QY.Cruz; #8008; 1:1000), KIM-1 (CST; #14971; 1:1000), p-PP2Ac (Thermo Fisher; PA5-36874), PP2Ac (CST; #2259; 1:1000), TNF-α (Santa Cruz; sc-515765; 1:1000), β-actin (Bioss; 0061R; 1:2000). Total protein was loaded

(10) The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cellsCell communication and signaling : CCSApril 3, 2024Nguyen A, Mustafa AM, Leydecker AK, Halilovic M, Murr J, Butter F, Krämer OH.Antibodies were from Cell Signaling, Frankfurt/Main, Germany: PP2A-A (cs-2039), 1:1.000; PP2A-C (cs-2259), 1:1.000; E-cadherin (cs-3795), 1:500; p-AKT (Serine-473; S473) (cs-9271S), 1:1.000; p-ERK1/p-ERK2

(11) Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stressBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieDecember 1, 2023Peyman M, Barroso E, Turcu AL, Estrany F Jr, Smith D, Jurado-Aguilar J, Rada P, Morisseau C, Hammock BD, Valverde ÁM, et al.Santa Cruz Biotechnology Inc., Dallas, TX, USA), phosphorylated NF-κB p65 Ser536 (#3036s, Cell Signalling Technology), PP2A (#2259, Cell Signaling Technology), p53 (2524T, Cell Signaling Technology), sEH (sc-25797, Santa Cruz Biotechnology Inc

(12) PP2Ac knockdown attenuates lipotoxicity‑induced pancreatic β‑cell dysfunction and apoptosisExperimental and Therapeutic MedicineOctober 10, 2023Zhengwei Zhang, Beier Tong, Jie Liu, Jieyuan Feng, Linyang Song, Huawei Wang, Mengting Ke, Chengkai Xu, Yancheng XuAnti-β-actin (1:50,000; cat. no. 66009-1-Ig; Proteintech Group, Inc.), anti-PP2Ac (1:2,000; cat. no. 2259s; CST Biological Reagents Co., Ltd.), anti-microtubule-associated protein 1 light chain 3 b (LC3B; 1:2,000;

(13) Alterations in iron content, iron-regulatory proteins and behaviour without tau pathology at one year following repetitive mild traumatic brain injuryActa neuropathologica communicationsJuly 18, 2023Juan SMA, Daglas M, Truong PH, Mawal C, Adlard PA.subunit,Rabbit,1:1000,Cell Signaling Technology,2290 PP2A C subunit,Rabbit,1:1000,Cell Signaling Technology,2259 GSK3β,Rabbit,1:1000,Cell Signaling Technology,9315 p-GSK3β,Rabbit,1:1000,Cell Signaling Technology,9336 Pin-1,Rabbit,1:1000,Cell Signaling Technology

(14) Quercetagitrin Inhibits Tau Accumulation and Reverses Neuroinflammation and Cognitive Deficits in P301S-Tau Transgenic MiceMolecules (Basel, Switzerland)May 8, 2023Zhong S, Ye J, Deng Y, Zhang M, Zou M, Yao X, Xiao S.(HW181, SAB, Los Angeles, CA, USA, 1:1000), T22 (ABN45S, EMD Millipore, Darmstadt, Germany), PP2A (2259T, CST, Danvers, MA, USA), GSK3β (93926, abcam, Cambridge, UK, 1:1000), p-GSK3β (75745, abcam, Cambridge,

(15) Blockade of Type 2A Protein Phosphatase Signaling Attenuates Complement C1q-Mediated Microglial Phagocytosis of Glutamatergic Synapses Induced by Amyloid FibrilsMolecular NeurobiologyMarch 1, 2023Jiang Wu, Jijun Xu, Mohamed Naguib, Bihua Biethe following primary antibodies: monoclonal anti-PP2A antibody (1:1000; Cell Signaling Technology, #2259), anti-FMRP antibody (1:1000; Cell Signaling, 7104), monoclonal anti-pFMRP antibody (1:1000; Thermo

(16) Quercetin alleviates diastolic dysfunction and suppresses adverse pro-hypertrophic signaling in diabetic ratsFront Endocrinol (Lausanne)December 8, 2022Linda Bartosova, Csaba Horvath, Peter Galis, Kristina Ferenczyova, Barbora Kalocayova, Adrian Szobi, Adriana Duris-Adameova, Monika Bartekova, Tomas RajtikCell Signaling, USA), phospho-T286-CaMKII (ab171095, Abcam, UK), PPP1CB (ab53315, Abcam, UK), PP2A C Subunit (#2259, Cell Signaling, USA), Phospho-Akt (Thr308) (#4056, Cell Signaling, USA), proBNP (ab239514, Abcam, UK),

(17) G Protein-Coupled Receptor 37L1 Modulates Epigenetic Changes in Human Renal Proximal Tubule CellsInternational journal of molecular sciencesNovember 21, 2022Armando I, Cuevas S, Fan C, Kumar M, Izzi Z, Jose PA, Konkalmatt PR.Cell Signaling Technology), anti-phospho-PI3K (catalog#4228, Cell Signaling Technology), anti-PP2A (catalog#2259, Cell Signaling Technology), anti-DNMT1 (catalog#5032, Cell Signaling Technology), anti-mTOR (catalog#2983,

(18) Fine-Tuning of mTORC1-ULK1-PP2A Regulatory Triangle Is Crucial for Robust Autophagic Response upon Cellular StressBiomoleculesOctober 28, 2022Hajdú B, Holczer M, Horváth G, Szederkényi G, Kapuy O.2603S), antiPP2A-Tyr307-P (Sigma-Aldrich, SAB4503975), antiPP2A C Subunit (Cell Signaling Technology, 2259S) and antiGAPDH (Santa Cruz, 6C5), HRP conjugated secondary antibodies (Cell Signaling Technology, 7074S,

(19) PKC-mediated phosphorylation and activation of the MEK/ERK pathway as a mechanism of acquired trastuzumab resistance in HER2-positive breast cancerFront Endocrinol (Lausanne)October 18, 2022Jeanesse Scerri, Christian Scerri, Felix SchÃ¤fer-Ruoff, Simon Fink, Markus Templin, Godfrey GrechphosphoThr638/Thr641,Cell Signaling,9375,Rb pAb,980,1570,1473,-0.68,-0.09 PI3K,PP2A C,Cell Signaling,2259,Rb mAb,5653,3171,2571,0.83,-0.30 PI3K,PP2A C - phosphoTyr307,R&D,AF3989,Rb pAb,4986,20990,10084,-2.07,-1.06 PI3K,PTEN,Cell Signaling

(20) Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibitioneLifeAugust 4, 2022Yitong Li, Vijaya Kumar Balakrishnan, Michael Rowse, Cheng-Guo Wu, Anastasia Phoebe Bravos, Vikash K Yadav, Ylva Ivarsson, Stefan Strack, Irina V Novikova, Yongna XingPP2Ac and Actin protein levels were detected by anti-PP2Ac antibody (Cell Signaling Technology, Cat#: 2259, 1:1000) and anti-β-Actin antibody (Cell Signaling Technology, Cat#: 3700, 1:1000), respectively. The

Be the First to Write a Review!

PP2A C Subunit (52F8) Rabbit mAb

PP2A C Subunit (52F8) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (71)

Reviews

PP2A C Subunit (52F8) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map