PKA RI-alpha (D54D9) Rabbit mAb 5675S from Cell Signaling Technology

Product Specs
ItemPKA RI-alpha (D54D9) Rabbit mAb
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number5675S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Hm, Mk
TargetPRKAR1A
HostRabbit
NCBI Gene AliasesACRDYS1, ADOHR, CAR, CNC, CNC1, PKR1, PPNAD1, PRKAR1, TSE1
ClonalityMonoclonal
NCBI Full Gene Nameprotein kinase cAMP-dependent type I regulatory subunit alpha
Research AreaCa, cAMP and Lipid Signaling
IsotypeIgG
CloneD54D9
Molecular Weight48

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Inhibition of phosphodiesterase 4D suppresses mTORC1 signaling and pancreatic cancer growthJCI insightJuly 10, 2023Jeong MH, Urquhart G, Lewis C, Chi Z, Jewell JL.(catalog 9197), mTOR (catalog 2972), mLST8 (catalog 3274), PKA Catα (catalog 4782), PKA RIα (catalog 5675), pPKA substrate (RRXS/T; catalog 9621) (all Cell Signaling Technology); Raptor (Cell Signaling Technology,

(2) Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanismseLifeJanuary 24, 2023Gary K L Chan, Samantha Maisel, Yeonjoo C Hwang, Bryan C Pascual, Rebecca R B Wolber, Phuong Vu, Krushna C Patra, Mehdi Bouhaddou, Heidi L Kenerson, Huat C Lim, et al.(CST#12456), MAPK1/3 pThr202/Thr204 (CST#4370), MAPK1/3 (CST#4695), PKAC-α (CST#4782), PKAR1a (CST#5675), FLAG (Sigma#F1804), Actin (CST#3700), Vinculin (CST#13901), or COXIV (CST#5247). Afterward, blotted

(3) HIV Activates the Tyrosine Kinase Hck to Secrete ADAM Protease-Containing Extracellular VesiclesEBioMedicineFebruary 1, 2018Lee JH, Ostalecki C, Zhao Z, Kesti T, Bruns H, Simon B, Harrer T, Saksela K, Baur AS.

(4) t-Darpp stimulates protein kinase A activity by forming a complex with its RI regulatory subunitCellular SignallingDecember 1, 2017Dirk Theile, Shuhui Geng, Erin C. Denny, Jamil Momand, Susan E. Kanet-Darpp, Cell Signaling #2306), phospho-Darpp Thr75 (Cell Signaling #2301), PKA-RIα (Cell Signaling #5675), PKA-RIβ (ThermoFisher Scientific #PA5-13798), PKA-RIIα (BD Biosciences #612242), PKA-RIIβ (BD Biosciences

(5) DACH1 suppresses breast cancer as a negative regulator of CD44Scientific reportsJune 28, 2017Xu H, Yu S, Yuan X, Xiong J, Kuang D, Pestell RG, Wu K.

(6) Factors Influencing Business Intelligence Data Collection StrategiesThe Indonesian Journal of Accounting ResearchMay 23, 2017Hanif Faidz Rahadian, Dekar Urumsah2 Item INS 3 Item INS 4 Loading 0,7640 0,9132 0,9039 0,8863 0,6435 0,7581 0,7616 0,7818 0,8445 0,9431 0,5675 0,8888 Item CST 1 Item CST 2 Item CST 3 Item CST 4 Item OTR 1 Item OTR 2 Item OTR 3 Item OTR 4 0,6301 0,9249 0,8817 0,9825 0,8083 0,9024 0,9089 0,8711 Item

(7) The GCN5-CITED2-PKA signalling module controls hepatic glucose metabolism through a cAMP-induced substrate switchNature communicationsNovember 22, 2016Sakai M, Tujimura-Hayakawa T, Yagi T, Yano H, Mitsushima M, Unoki-Kubota H, Kaburagi Y, Inoue H, Kido Y, Kasuga M, et al.1:1,000), to Ser157-phosphorylated VASP (#3111, 1:1,000), to PKACα (#5842, 1:1,000) and to PKARIα (#5675, 1:1,000) were obtained from Cell Signaling. Antibodies to GCN5 (sc-20698, 1:500; sc-365321, 1:500),

(8) Extracellular serglycin upregulates the CD44 receptor in an autocrine manner to maintain self-renewal in nasopharyngeal carcinoma cells by reciprocally activating the MAPK/β-catenin axisCell death & diseaseNovember 3, 2016Chu Q, Huang H, Huang T, Cao L, Peng L, Shi S, Zheng L, Xu L, Zhang S, Huang J, et al.

(9) Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinomaPediatric researchJuly 1, 2016Riggle KM, Riehle KJ, Kenerson HL, Turnham R, Homma MK, Kazami M, Samelson B, Bauer R, McKnight GS, Scott JD, et al.Jose, CA), p-p44/42 MAPK (Erk1/2) (Thr202/Tyr204), total p44/42 MAPK (Erk1/2), and PKA RIα (9101, 9102, 5675, Cell Signaling, Danvers, MA), and β-Actin (A5441, Sigma, St. Louis, MO). Densitometry analysis was

(10) Hepatocyte Insulin Signaling is Required for Feeding-Induced Lipogenesis but Dispensable for the Suppression of Glucose ProductionCell MetabolismJune 14, 2016Paul M. Titchenell et al.p4EBP1 (#2855), 4EBP1 (#9452), Tsc1 (#6935), pPKA substrates (#9624), pS133 Creb (#9198), RI alpha (#5675) were from Cell Signaling Technology. Igfbp1 (sc-6000) and Tsc2 (sc-893) were from Santa Cruz. pPRAS40

(11) HIV-Nef and ADAM17-Containing Plasma Extracellular Vesicles Induce and Correlate with Immune Pathogenesis in Chronic HIV InfectionEBioMedicineApril 1, 2016Jung-Hyun Lee et al.

(12) Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic ß-cells via protein kinase AMolecular MetabolismFebruary 3, 2015Sindhu Rajan, Lorna M. Dickson, Elizabeth Mathew, Caitlin M.O. Orr, Johanne H. Ellenbroek, Louis H. Philipson, Barton Wicksteed(Cell Signaling Technologies, cat # 4820, diluted 1:1000); anti-PKA-RIα (Cell Signaling Technologies, cat # 5675, diluted 1:1000); anti-PKA RIIα (BD Transduction Laboratories, cat # 612242, diluted 1:1000); anti-PKA-RIIβ

(13) Selective Expression of a Dominant-Negative Type Ια PKA Regulatory Subunit in Striatal Medium Spiny Neurons Impairs Gene Expression and Leads to Reduced Feeding and Locomotor ActivityThe Journal of NeuroscienceApril 2, 2014Linghai Yang, Merle L. Gilbert, Ruimao Zheng, G. Stanley McKnightantibodies: anti-RII␤ (BD Transduction Laboratory; #610626), anti-RI␣ (Cell Signaling Technology; #5675), anti-c-fos (Santa Cruz Biotechnology; sc-7202), and antiphospho-CREB (S133; Cell Signaling Technology;

(14) Pain modulators regulate the dynamics of PKA-RII phosphorylation in subgroups of sensory neuronsJournal of cell scienceJanuary 1, 2014Isensee J, Diskar M, Waldherr S, Buschow R, Hasenauer J, Prinz A, Allgöwer F, Herberg FW, Hucho T.Cell Science (2014) 127, 216–229 doi:10.1242/jcs.136580 RESEARCH ARTICLE (Cell Signaling, no. 5675; WB 1:5000, IC 1:1000), rabbit polyclonal antiRIb (Abm, no. Y051648; WB 1:2500, IC 1:500), mouse monoclonal

(15) Acamprosate Suppresses Ethanol-Induced Place Preference in Mice With Ethanol Physical DependenceJournal of Pharmacological SciencesAugust 2, 2013Kazuhiro Kurokawa, Koji Mizuno, Masahiro Shibasaki, Masaya Higashioka, Michiko Oka, Masaaki Hirouchi, Seitaro Ohkumaphosphor-CREB (Ser133) (rabbit polyclonal anti-p-CREB, #4276), and PKARI-a (rabbit polyclonal anti-PKA, #5675) were purchased from Cell Signaling Techonology, Inc. (Boston, MA, USA). Mouse anti-b-actin (sc-47778)

(16) Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and humanEMBO molecular medicineAugust 1, 2013Chang YC, Yu YH, Shew JY, Lee WJ, Hwang JJ, Chen YH, Chen YR, Wei PC, Chuang LM, Lee WH.(GeneTex 627408), C/EBPβ (BioLegend 606201), PKA C-α (Cell Signalling 4782), PKA-RI-α (Cell Signalling 5675), phospho-CREB (Millipore 05-667) and CREB (Cell Signalling 9104) was used. Cell culture The 3T3-L1

(17) Secreted PLA2 induces proliferation in astrocytoma through the EGF receptor: another inflammation-cancer linkNeuro-OncologyOctober 1, 2010Marita Hernandez, RubÃ©n Martin, Miriam Daniela Garcia-Cubillas, Patricia Maeso-Hernandez, MarÃa Luisa NietoTriggering of degranulation in mast cells by exogenous type II phospholipase A2. J Immunol. 1993; 151:5675 –5684. 43. Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell. 2000;103:211 –225. 44.

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PKA RI-alpha (D54D9) Rabbit mAb

PKA RI-alpha (D54D9) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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PKA RI-alpha (D54D9) Rabbit mAb from Cell Signaling Technology

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