p70 S6 Kinase (49D7) Rabbit mAb from Cell Signaling Technology

Yes, the p70 S6 Kinase (49D7) Rabbit mAb has been utilized in various studies to investigate its role in cancer signaling pathways, particularly in relation to the mTOR signaling pathway. For instance, it has been referenced in research examining the activation of p70 S6 Kinase in response to growth factors and its implications in cancer cell proliferation and survival.

The p70 S6 Kinase (49D7) Rabbit mAb is specifically designed for use in Western Blot applications, where it has been shown to effectively detect endogenous levels of total p70 S6 kinase protein, as well as p85 S6 kinase, in human samples.

This antibody has been cited in research investigating the AKT-mTOR signaling pathway's involvement in pathological cardiac hypertrophy. For example, studies have demonstrated that p70 S6 Kinase plays a critical role in mediating hypertrophic responses in cardiomyocytes, highlighting its importance in cardiac health and disease.

The p70 S6 Kinase (49D7) Rabbit mAb is reactive with human samples, making it suitable for studies focused on human biology and disease mechanisms, particularly in the context of cancer and cellular signaling pathways.