MAML2 Antibody 4618S from Cell Signaling Technology

Product Specs
ItemMAML2 Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number4618S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
TargetMAML2
HostRabbit
NCBI Gene AliasesMAM-3, MAM2, MAM3, MLL-MAML2
NCBI Full Gene Namemastermind like transcriptional coactivator 2
ClonalityPolyclonal
Research AreaDevelopmental Biology
Molecular Weight160

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Transactivation of TrkB Receptors by Oxytocin and Its G Protein-Coupled ReceptorFrontiers in molecular neuroscienceJanuary 1, 2022Mitre M, Saadipour K, Williams K, Khatri L, Froemke RC, Chao MV.(Y816),"Made in the Chao lab (Rajagopal et al., 2004; Arevalo et al., 2006)" p-TrkB,Cell Signaling (#4618) RatTrkB,mouse monoclonal antibody BD Transduction (#610102) Total TrkB,Goatantibody R&D Systems (#AF1494), p-MAPK/ERK,Cell Signaling

(2) Targeting Notch and EGFR signaling in human mucoepidermoid carcinomaSignal Transduction and Targeted TherapyDecember 1, 2021Wei Ni, Zirong Chen, Xin Zhou, Rongqiang Yang, Mu Yu, Jianrong Lu, Frederic J. Kaye, Lizi Wuanalyses were performed as described previously.56 The following antibodies were used: anti-MAML2 (4618), anti-phospho-EGFR (Tyr 1068) (3777), anti-EGFR (2232), anti-cleaved-NOTCH1 (Val1744) (4147), anti-NOTCH1

(3) The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinomaJCI insightApril 8, 2021Chen Z, Ni W, Li JL, Lin S, Zhou X, Sun Y, Li JW, Leon ME, Hurtado MD, Zolotukhin S, et al.immunoblotting as previously described (32). The following antibodies were used: anti-MAML2 TAD (catalog 4618), anti–phospho-RB (Ser807/811, catalog 8516), anti–phospho-EGF receptor (Tyr1068, catalog 3777), and

(4) Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanismeLifeApril 16, 2020Yi Kuang et al.monoclonal) CST Cat# 11959; RRID:AB_2797778 WB (1:1000) Antibody anti-MAML2 (Rabbit polyclonal) CST Cat# 4618; RRID:AB_2139273 WB (1:1000) Antibody anti-MAML3 (Rabbit polyclonal) Bethyl Cat# A300-684A; RRID:AB_2266032 WB

(5) A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastomaNature communicationsApril 4, 2019van Groningen T, Akogul N, Westerhout EM, Chan A, Hasselt NE, Zwijnenburg DA, Broekmans M, Stroeken P, Haneveld F, Hooijer GKJ, et al.monoclonal NCAM1 (CD56) antibody (MRQ-42, Cell Marque, 1:100 dilution) or rabbit polyclonal MAML2 antibody (#4618, Cell Signaling Technology, 1:100). This was followed by incubation with secondary Brightvision poly-anti-Rabbit

(6) CRTC1-MAML2 fusion-induced lncRNA LINC00473 expression maintains the growth and survival of human mucoepidermoid carcinoma cellsOncogeneApril 1, 2018Chen Z, Lin S, Li JL, Ni W, Guo R, Lu J, Kaye FJ, Wu L.performed as previously described40. The antibodies were used in this study including anti-MAML2 (CST-4618, Cell Signaling Technology), anti-CREB (06-863, Millpore), anti-β-ACTIN (SC-47778, Santa Cruz) and anti-β-TUBULIN

(7) Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathwayScientific reportsMay 2, 2017Rippe C, Zhu B, Krawczyk KK, Bavel EV, Albinsson S, Sjölund J, Bakker ENTP, Swärd K.Cell Signaling Technology), NOTCH2/NICD (#5732, Cell Signaling Technology), FRYL (ab95065, Abcam), MAML2 (#4618, Cell Signaling Technology), TPM1 (#3910, Cell Signaling Technology), MYLK (ab76092, Abcam), TAGLN (ab14106,

(8) Gene expression profiling analysis of CRTC1-MAML2 fusion oncogene-induced transcriptional program in human mucoepidermoid carcinoma cellsBMC cancerOctober 26, 2015Chen J, Li JL, Chen Z, Griffin JD, Wu L.dry milk. The membranes were then incubated with the antibodies (anti-MAML2 TAD, Cell signaling CST-4618; or anti-β-actin, Santa Cruz sc-47778) overnight at 4 °C, washed, and then incubated with a horseradish

(9) CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvementProceedings of the National Academy of Sciences of the United States of AmericaAugust 12, 2014Amelio AL, Fallahi M, Schaub FX, Zhang M, Lawani MB, Alperstein AS, Southern MR, Young BM, Wu L, Zajac-Kaye M, et al.conventional methodologies. Antibodies included FLAG–M2 HRP conjugate (Sigma; A8592), MAML2 (Cell Signaling; 4618), MAML2 (Bethyl Labs; A300-681A), MYC N-262 (Santa Cruz; sc-764), MYC 9E10 (Santa Cruz; sc-40), and

(10) Aberrantly activated AREG-EGFR signaling is required for the growth and survival of CRTC1-MAML2 fusion-positive mucoepidermoid carcinoma cellsOncogeneJuly 17, 2014Chen Z, Chen J, Gu Y, Hu C, Li JL, Lin S, Shen H, Cao C, Gao R, Li J, et al.purchased from commercial sources including anti-MAML2 (Cell Signaling Technology, Danvers, MA, USA; CST-4618), anti-MAML2 (Bethyl Laboratories, Montgomery, TX, USA; A300-681A); anti-phospho-EGF receptor (Tyr1068;

(11) Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivoDevelopment (Cambridge, England)December 1, 2011Oyama T, Harigaya K, Sasaki N, Okamura Y, Kokubo H, Saga Y, Hozumi K, Suganami A, Tamura Y, Nagase T, et al.Fig. 1D and Fig. 9B; anti-MAML1 (A300-673A; Bethyl Laboratories, Montgomery, TX, USA) and anti-MAML2 (#4618; Cell Signaling Technology, Danvers, MA, USA) in Fig. 9A,C,D; anti-NOTCH1 (sc-6014; Santa Cruz Biotechnology,

(12) High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomasOncogeneApril 14, 2011Köchert K, Ullrich K, Kreher S, Aster JC, Kitagawa M, Jöhrens K, Anagnostopoulos I, Jundt F, Lamprecht B, Zimber-Strobl U, et al.cell or nuclear extracts were used. Primary antibodies were: anti-MAML1 and anti-MAML2 (#4608 and #4618, Cell Signaling, Boston, MA, USA), anti-MAML3 (NB100-2129, Novus Biologicals, Cambridge, UK), anti-cleaved

(13) Escherichia coli Subtilase Cytotoxin Induces Apoptosis Regulated by Host Bcl-2 Family Proteins Bax/BakInfection and ImmunityNovember 1, 2010Kerrie L. May, James C. Paton, Adrienne W. Patonrabbit antisurvivin (71G4B7) (catalog no. 2808) (used for MEFs) were from Cell Signaling. Anti-Puma (catalog no. P-4618) and anti-␤-actin (AC-74) (catalog no. A-5316) were from Sigma. Images were captured using a Kodak 4000MM

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MAML2 Antibody

MAML2 Antibody from Cell Signaling Technology

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Cell Signaling Technology

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MAML2 Antibody from Cell Signaling Technology

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