Akt2 (5B5) Rabbit mAb 2964S from Cell Signaling Technology

Product Specs
ItemAkt2 (5B5) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number2964S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
TargetAkt2
HostRabbit
NCBI Gene AliasesHIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA
ClonalityMonoclonal
NCBI Full Gene NameAKT serine/threonine kinase 2
Research AreaPI3K / Akt Signaling
IsotypeIgG
Clone5B5
Molecular Weight60

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Cytoskeletal Protein 4.1R Inhibits BCR-Mediated B-Cell Activation by Restraining AKT1 PhosphorylationCellsJuly 13, 2026Yuying Guo, Dandan Fan, Denghui Liu, Qi Shao, Siyao Sang, Yuting Niu, Lixiang Chen, Taotao Liang1:1000), anti-Phospho-AKT1 (9018, Cell Signaling Technology, Danvers, MA, USA; 1:1000), anti-AKT2 (2964, Cell Signaling Technology, Danvers, MA, USA; 1:1000), anti-Phospho-AKT2 (8599, Cell Signaling Technology,

(2) Optineurin modulates mTORC2/AKT/STAT3 signaling to control MHC class II expression and adaptive immunity against HSV-1Cell ReportsApril 16, 2026Rashmi Kadam, Chandrashekhar Patil, Leonid Feferman, Mark Maienschein-Cline, George Chlipala, Piyush Borole, Ilina Bhattacharya, Chima Orameh, Tara Nyugen, Henry Tseng, et al.,Cell Signaling Technology,Cat#75692 RRID:AB_2716309 Rabbit monoclonal anti-AKT2,Cell Signaling Technology,Cat#2964 RRID:AB_331162 Rabbit monoclonal anti-RICTOR,Cell Signaling Technology,Cat#2114 RRID:AB_2179963 Rabbit

(3) AKT2 Modulates Astrocytic Nicotine Responses In VivoGliaOctober 1, 2025Andrew M. Lombardi, Mina Griffioen, Helen Wong, Ryan Milstead, Curtis Borski, Erin Shiely, Myra E. Bower, Emily Schmitt, Lauren LaPlante, Marissa A. Ehringer, et al.reports (Gusel’nikova & Korzhevskiy, 2015; Levenga et al., 2017). The AKT2 antibody used (Cell Signaling, 2964, diluted 1:100) stained astrocytes exclusively, consistent with previous reports (Levenga et al., 2017;

(4) Microneurotrophin BNN27 Exerts Significant Anti-Inflammatory Effects on Murine T-Lymphocytes Following CFA-Induced Inflammatory PainInt J Mol SciJune 8, 2025Smaragda Poulaki, Aikaterini Kalantidou, Ioanna Lapi, Achille Gravanis, Maria Venihakiwith antibodies for AKT1 and AKT2 (total/phospho 1:1000, rabbit; Cell Signaling, Danvers, MA, cat# 2964S and 8599S, respectively). To detect the bands of interest, we used the Benchmark Pre-Stained Protein

(5) Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation modelMolecular OncologyMarch 25, 2025Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, et al.Afterwards, the membrane was incubated with primary antibodies against AKT1 (C73H10, #2938), AKT2 (5B5, #2964 or L79B2, #5239), and AKT3 (L47B1, #8018) (all purchased from Cell Signaling Technology, Danvers, MA,

(6) Akt1 deficiency does not affect fiber type composition or mitochondrial protein expression in skeletal muscle of male micePhysiological ReportsSeptember 10, 2024Tatsuya Miyaji, Ryuichi Kasuya, Atsushi Sawada, Daisuke Sawamura, Yu Kitaoka, Mitsunori MiyazakiAB3242) were from Merck (Darmstadt, Germany). Akt (pan, Cat#: 4691), Akt1 (Cat#: 2967), Akt2 (Cat#: 2964), ACLY (Cat#: 13390), phospho‐FoxO1 (Thr24)/FoxO3a (Thr32) (Cat#: 9464), and FoxO1 (Cat#: 2880) were

(7) mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3bJ Clin InvestApril 1, 2024Kahealani Uehara, Won Dong Lee, Megan Stefkovich, Dipsikha Biswas, Dominic Santoleri, Anna Garcia Whitlock, William Quinn, Talia Coopersmith, Kate Townsend Creasy, Daniel J. Rader, et al.were used for immunoblotting, all from Cell Signaling Technology: p-AKT (CST no. 4060), AKT2 (CST no. 2964), p-S6 (CST no. 2215), S6 (CST no. 2217), HSP90 (CST no. 4874), GCK (Gift from Magnuson Lab), p-GS (CST

(8) Erianin promotes apoptosis and inhibits Akt-mediated aerobic glycolysis of cancer cellsJ CancerMarch 4, 2024Shuangze Han, Sijin Chen, Jidong Wang, Sheng Huang, Yeqing Xiao, Gaoyan Deng(#9664), Bax (#14796), VDAC1 (#4661), α-tubulin (#2144), cytochrome c (#4280), Akt1 (#2938), Akt2 (#2964), p-GSK3β (#5558), β-actin (#3700), anti-rabbit IgG HRP (#7074), and anti-mouse IgG HRP (#7076) were

(9) Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonismMolecular MetabolismFebruary 1, 2024Elizabeth Nunn, Natasha Jaiswal, Matthew Gavin, Kahealani Uehara, Megan Stefkovich, Karima Drareni, Ryan Calhoun, Michelle Lee, Corey D. Holman, Joseph A. Baur, et al.following antibodies were used (all from Cell Signaling Technology): pan-Akt (Cat# 4691), Akt2 (Cat# 2964), p-Akt (Ser473) (Cat# 4060), p-Akt2 (Ser474) (Cat# 8599), Hsp90 (Cat# 4874). 4.6 Serum insulin, glycerol,

(10) mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3bJournal of Clinical InvestigationJanuary 30, 2024Kahealani Uehara, Won Dong Lee, Megan Stefkovich, Dipsikha Biswas, Dominic Santoleri, Anna E. Garcia Whitlock, William J. Quinn III, Talia N. Coopersmith, Kate Townsend Creasy, Daniel J. Rader, et al.were used for immunoblotting, all from Cell Signaling Technology: p-AKT (CST no. 4060), AKT2 (CST no. 2964), p-S6 (CST no. 2215), S6 (CST no. 2217), HSP90 (CST no. 4874), GCK (Gift from Magnuson Lab), p-GS (CST

(11) Oncogenic β-catenin-driven liver cancer is susceptible to methotrexate-mediated disruption of nucleotide synthesisChinese Medical JournalJanuary 20, 2024Fangming Liu, Yuting Wu, Baohui Zhang, Shuhui Yang, Kezhuo Shang, Jie Li, Pengju Zhang, Weiwei Deng, Linlin Chen, Liang Zheng, et al.with primary antibodies against β-catenin (#9587, Cell Signaling Technology, Danvers, MA, USA), AKT2 (#2964, Cell Signaling Technology), carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

(12) Oncogenic β-catenin-driven liver cancer is susceptible to methotrexate-mediated disruption of nucleotide synthesisChin Med J (Engl)August 23, 2023Fangming Liu, Yuting Wu, Baohui Zhang, Shuhui Yang, Kezhuo Shang, Jie Li, Pengju Zhang, Weiwei Deng, Linlin Chen, Liang Zheng, et al.with primary antibodies against β-catenin (#9587, Cell Signaling Technology, Danvers, MA, USA), AKT2 (#2964, Cell Signaling Technology), carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

(13) Synthesis and Characterization of Colistin-Functionalized Silica Materials for Rapid Capture of Bacteria in WaterMoleculesNovember 28, 2022Jingli Qiu, Jianli Li, Xiaoxi Du, Tong Zhou, Bingbing Xie, Limin HeSiO2@NH2@COOH@CST were tested (Figure S3A). For all three silica gels, the same absorption bands at 2964 cm−1 and 2938 cm−1 were observed, which were mainly characteristic stretching vibrations of the CH2

(14) Microglia-Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse ModelCellsNovember 9, 2022Boyce M, Xin Y, Chowdhury O, Shang P, Liu H, Koontz V, Strizhakova A, Nemani M, Hose S, Zigler JS Jr, et al.Waltham, MA, USA; Cat# 11-0141-81), anti-AKT2 (Cell Signaling Technologies, Danvers, MA, USA; Cat# 2964S), Alexa fluor 488-tagged integrin β1 (Santa Cruz Biotechnology, Dallas, TX, USA; Cat# sc-374429 AF488),

(15) Sex Differences in Glomerular Protein Expression and Effects of Soy-Based Diet on Podocyte SignalingCanadian Journal of Kidney Health and DiseaseSeptember 30, 2022Afreeda Mahesaniya, Casey R. Williamson, Ava Keyvani Chahi, Claire E. Martin, Alexander E. Mitro, Peihua Lu, Laura A. New, Katrina L. Watson, Roger A. Moorehead, Nina JonesCell Signaling Technology), rabbit anti-Akt1 (C73H10, 2938, Cell Signaling Technology), rabbit anti-Akt2 (5B5, 2964, Cell Signaling Technology), rabbit anti-Akt3 (4059, Cell Signaling Technology), rabbit anti-ERK1/2

(16) AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decayMolecular cellAugust 4, 2022Cho H, Abshire ET, Popp MW, Pröschel C, Schwartz JL, Yeo GW, Maquat LE.(1: 1000),Cell Signaling,"#4060, #4051" α-AKT1 (1: 1000),Cell Signaling,#2938 α-AKT2 (1: 1000),Cell Signaling,#2964 α-AKT3 (1: 1000),Cell Signaling,#3788 α-ROBO1 (1: 1000),Proteintech,20219-1-AP α-ROBO2 (1: 1000),Cell Signaling

(17) Global-run on sequencing identifies Gm11967 as an Akt-dependent long noncoding RNA involved in insulin sensitivityiScienceJune 17, 2022Dominic Santoleri, Hee-Woong Lim, Matthew J. Emmett, Julian Stoute, Matthew J. Gavin, Jaimarie Sostre-ColÃ³n, Kahealani Uehara, Jaclyn E. Welles, Kathy Fange Liu, Mitchell A. Lazar, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, HSP90,Cell Signaling Technology,Cat# 4874; RRID: AB_2121214 AKT2,Cell Signaling Technology,Cat# 2964; RRID: AB_331162 P-AKT2 (Ser474),Cell Signaling Technology,Cat# 8599; RRID: AB_26303478 P-PRAS40 (Thr246),Cell Signaling Technology

(18) Platelet-Derived miR-126-3p Directly Targets AKT2 and Exerts Anti-Tumor Effects in Breast Cancer Cells: Further Insights in Platelet-Cancer InterplayInternational journal of molecular sciencesMay 13, 2022Sibilano M, Tullio V, Adorno G, Savini I, Gasperi V, Catani MV.antibodies used were anti-PIK3R2 (1:1000; cod. ab180967, Abcam, Cambridge, England), anti-AKT2 (1:500; cod. 2964S, Cell Signaling Technology, Danvers, MA, USA), anti-cofilin (1:1000; cod. CP1131, ECM Biosciences, Versailles,

(19) MYPT1/PP1-Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial-Mesenchymal Transition in Fibrosis through Control of Multiple Families of GenesAdvanced science (Weinheim, Baden-Wurttemberg, Germany)May 1, 2022Zhang L, Wang L, Hu XB, Hou M, Xiao Y, Xiang JW, Xie J, Chen ZG, Yang TH, Nie Q, et al.sc‐514261), mouse anti‐AKT1(1:1000, Santa Cruz, sc‐5298), rabbit anti‐AKT2 (1:1000, Cell Signaling Technology#2964), rabbit anti‐pan AKT(1:1000, Cell Signaling Technology#4691), rabbit anti‐pGSK3β S9(1:1000, Cell Signaling Technology

(20) Activation of Liver mTORC1 Protects Against NASH via Dual Regulation of VLDL-TAG Secretion and De Novo LipogenesisCellular and Molecular Gastroenterology and HepatologyFebruary 28, 2022Kahealani Uehara, Jaimarie Sostre-Colón, Matthew Gavin, Dominic Santoleri, Kelly-Ann Leonard, René L. Jacobs, Paul M. Titchenellgels. The following primary antibodies were used for immunoblotting: p-Akt (CST #4060), Akt2 (CST #2964), p-S6 (CST #2215), S6 (CST #2217), p-4E-BP1 (CST #236B4), 4E-BP1 (CST #9452), Tsc1 (CST #6935), CCTα

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Akt2 (5B5) Rabbit mAb

Akt2 (5B5) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Akt2 (5B5) Rabbit mAb from Cell Signaling Technology

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