EGR1 (15F7) Rabbit mAb 4153S from Cell Signaling Technology

Product Specs
ItemEGR1 (15F7) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number4153S
Quantity100 µl
ApplicationsW, IP, IF-F, IF-IC, ChIP
ReactivityH, M, R
TargetEGR1
HostRabbit
NCBI Gene AliasesAT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225
ClonalityMonoclonal
NCBI Full Gene Nameearly growth response 1
Research AreaNeuroscience
IsotypeIgG
Clone15F7
Molecular Weight75

Questions and Answers

Can this antibody be used for studying EGR1 in mouse models?

Yes, the EGR1 (15F7) Rabbit mAb has been shown to work effectively in mouse models, as evidenced by its use in immunostaining for EGR1 in various studies, including those examining chondrocyte differentiation and neuronal activity in mice (, ).

Is this antibody suitable for use in immunohistochemistry?

The EGR1 (15F7) Rabbit mAb has been utilized in immunohistochemistry, as demonstrated in studies where it was employed to detect EGR1 protein levels in tissue sections, confirming its applicability in this technique (, ).

What applications has this antibody been cited in?

This antibody has been cited in various applications, including Western blotting, immunocytochemistry, immunofluorescence, immunoprecipitation, and chromatin immunoprecipitation, making it versatile for different experimental setups (, , ).

Are there any specific findings related to EGR1 that this antibody has helped uncover?

Yes, studies using this antibody have revealed important roles for EGR1 in processes such as chondrocyte terminal differentiation and decidualization in human endometrial stromal cells, highlighting its significance in developmental biology and reproductive health (, ).

Cell Signaling Technology

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Phone: 978-867-2388
Fax: 866-432-6112
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Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Hepatocyte SLCO4C1 is a cAMP uptake transporter for inhibiting lipogenesis and a therapeutic target for MASLDNature CommunicationsMarch 13, 2026Xiaojia Huang, Sen Liang, Nan Zhao, Jingjing Ding, Siyi Jiang, Changpei Gan, Huayu Zhang, Lei Zuo, Yangyang Li, Xiaoxun Zhang, et al.Subsequently, the digested chromatin fragments were probed with 1 µg anti-EGR1 antibody (CST, Boston, USA, Cat:4153S), positive control Histone H3 antibody (CST, Boston, USA, Cat:4620) or negative control Normal Rabbit

(2) Supercharging-enhanced nDIA-MS enables global profiling of drug-induced proteome solubility shiftsNature CommunicationsJanuary 30, 2026Yun Xiong, Huimin Zhang, Lin Tan, Bo Wei, John N. Weinstein, Philip L. LorenziCell Signaling Technology), SMAD2 (3103 T; Cell Signaling Technology), RB1 (9309 T; Cell Signaling Technology), EGR1 (4153 T; Cell Signaling Technology), NAB2 (sc-23867, Santa Cruz Biotechnology), SP100 (GTX131569, GeneTex),

(3) Scalable and multiplexed recorders of gene regulation dynamics across weeksNatureJanuary 26, 2026Lirong Zheng, Dongqing Shi, Yixiao Yan, Bingxin Zhou, Jormay Lim, Yongjie Hou, Bobae An, Jason K. Adhinarta, Michael Lin, BumJin Ko, et al.antibody (9198, Cell Signaling Technology), anti-pElk-1 (9186, Cell Signaling Technology), anti-Egr1 (4153, Cell Signaling Technology), anti-p-p44/42 MAPK (Erk1/2)(Thr202/Tyr204) (4370, Cell Signaling Technology),

(4) Neuronal hyperactivity becomes mTORC1 independent due to transcriptional changes in tuberous sclerosis complex disease modelsCell ReportsDecember 23, 2025Wardiya Afshar-Saber, Juan F. Ruiz, Isabel Gisser, Ziqin Yang, Leena Mehendale, Nicole A. Teaney, Rachel Hobson, Madison R. Glass, Truc T. Pham, Elizabeth Bainbridge, et al.buffered saline. Antibodies used were: BCL11B, Biolegend, #650602, 1:500; EGR1, Cell Signaling Technology, 4153S, 1:500. Quantitative PCR At P30, littermate Tsc2del/fl SynCre+ and Tsc2fl/fl SynCre-animals were euthanized

(5) Chronic Exposure to Cigarette Smoke Induces Pyroptosis in Pulmonary Epithelial Cells via EGR1/USP44/TRAF6 Axis in COPDJournal of Inflammation ResearchNovember 27, 2025Chaofan Cao, Zhaoshuang Zhong, Bo Wu, Bo Zou, Hui Jia, Jiahuan Xu, Guixian Xiao, Shuyue Xiaimmunoprecipitated at 4°C overnight using either a negative control IgG or 2.5 μg of EGR1 antibody (4153, CST, USA). The purified DNA was amplified using qRT-PCR with primers designed as outlined follow: USP44

(6) VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound ScreeningAdvanced ScienceOctober 27, 2025Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping Youincluding rabbit phospho‐NF‐κB p65 (Ser536) (93H1) (catalog no. 3033) and EGR1 (15F7) (catalog no. 4153), were obtained from Cell Signaling Technology. Secondary detection utilized HRP‐conjugated Affinipure Goat Anti‐Rabbit IgG (H+L

(7) EGR1 Mediates Riluzole-Induced Apoptosis in Osteosarcoma via the Yap/p73-Bax Signaling AxisbioRxivOctober 18, 2025Syeda Maryam Azeem, Shraddha ChandThakuri, Pooja Prakash Rao, Tamia Abbasi, Jannae McFarlane, Raisa Munira, Sahanama Porshe, Vinagolu K. Rajasekhar, John H. Healey, Shahana S. MahajanImmunoprecipitation was performed overnight using A/G beads with antibodies for EGR1 (Cell signaling #4153) at 1:50, YAP (Cell signaling #14074) at 1:50 dilution, p73 (Abcam #215038) at 0.544 mg/mL and pol II

(8) Spatiotemporal microenvironment landscape and malignant epithelial pattern transition in breast ductal carcinoma progressionJournal of Translational MedicineSeptember 24, 2025Xifu Cheng, Wenjuan Zeng, Bingzhe Yin, Jiawei Gui, Hengbin Zhang, Zhenxing Lv, Simin Zhang, Yao Zhouantibodies include FOXP3 (bs-10211R, BIOSS), IL2RA (af5105, AFFINITY), CD68 (ba3638, BOSTER), and EGR1 (4153s, CST). The next day, the slides were washed in PBS three times for 5 min each. After slight drying of

(9) Novel environment exposure drives temporally defined and region-specific chromatin accessibility and gene expression changes in the hippocampusNat CommunAugust 21, 2025Lisa Traunmüller, Erin E. Duffy, Hanqing Liu, Stella Sanalidou, Sebastian Krüttner, Elena G. Assad, Senmiao Sun, Naeem S. Pajarillo, Nancy Niu, Eric C. Griffith, et al.temperature with the following primary antibodies: Egr1 anti-rabbit (1:2000, Cell Signaling Technology #4153S) and c-Fos anti-guinea pig (1:3000, Synaptic Systems, #226308). Brain slices were subsequently washed

(10) USP53 Drives ethanol-induced myocardial injury by Promoting K63 Deubiquitination-dependent RIPK1 Activation at K377Research (Wash D C)August 14, 2025Jichen Pan, Xiaolin Liu, Xiao Li, Shanshan Wang, Yuliang Zhao, Chong Yuan, Dongdong Liu, Liyan Wang, Meng Zhang, Fengming Liu, et al.ab196436), MLKL (Immunoway, YM8455), cleaved caspase-3 (CST, 9661T), caspase-3 (CST, 9662T), EGR1 (CST, 4153T), ubiquitin (CST, 20326T), K63-linked ubiquitin (CST, 5621T), K48-linked ubiquitin (CST, 8081T), HA

(11) EGR1 Promotes Craniofacial Bone Regeneration via Activation of ALPL⁺PDGFD⁺ Periosteal Stem CellsAdvanced science (Weinheim, Baden-Wurttemberg, Germany)August 1, 2025Li Y, Lu D, Xu F, Yang J, Li D, Yang C, Chen X, Wang X, Qing J, Zhang H, et al.initial binding, the complexes were incubated with EGR1 antibody and IgG (Cell Signaling Technology, Cat#4153S and 2729), secondary antibody, and Hyperactive pA/G‐Transposon Pro (Vazyme, Cat#TD904). Trueprep Tagment

(12) Select early growth response (Egr) isoforms augment hypoxia inducible factor 2 (HIF-2) regulation of erythropoietin (Epo) gene expression in mammalsThe Journal of biological chemistryJuly 1, 2025Nagati JS, Dioum EM, Giardinetto CS, Mohiuddin SMG, Zhang Q, Garcia JA.protein) were precleared with magnetic protein G beads, then incubated with antibodies to Egr1 (Cat. No. 4153, Cell Signaling Technology) or Egr2 (Cat. No. ab63943, Abcam) for 2 h at 4 °C on a rotator. Magnetic

(13) Regression of hepatic fibrosis in gamma-irradiated rats by mycophenolate mofetil: potential role of Egr-1Naunyn-Schmiedeberg's Archives of PharmacologyJune 17, 2025Shereen Mohamed Galal, Dalia Mohamed Mostafa, Shereen Mohamed El kikiusing antibodies for early growth response 1 (Egr-1) (1:1000; Cell Signaling technology; USA, Cat. # 4153), alpha smooth muscle actin (α-SMA) (1:1000; Cell Signaling technology; USA, Cat. # 14968), TGF-β (1:1000;

(14) Tracing the molecular landscape of diabetic nephropathy: Insights from machine learning and experiment verificationJournal of Diabetes InvestigationJune 5, 2025Shahad W. Kattan, Ahmed M. Basri, Mohammad H. Alhashmi, Amany I. Almars, Reem Hasaballah Alhasani, Ifat Alsharif, Ikhlas A. Sindi, Ahmad H. Mufti, Iman S. Abumansour, Nasser A. Elhawary, et al.Cell Signaling Technology, MA, USA), GAPDH (4970, 1:5,000; Cell Signaling Technology, MA, USA), EGR1 (4153, 1:1,000; Cell Signaling Technology, MA, USA), FPR1 (80672, 1:1,000; Cell Signaling Technology, MA,

(15) Cellular crosstalk mediated by Meteorin-like regulating hepatic stellate cell activation during hepatic fibrosisCell death & diseaseMay 20, 2025Zhou Y, Wang G, Liu L, Song L, Hu L, Liu L, Xu L, Wang T, Liu L, Wang Y, et al.cat.19245S), Ubiquitin antibody (WB, 1:1000; cat. 43124S) and EGR1 antibody (WB, 1:1000; ChIP,1:50; cat. 4153S) were obtained from CST. PDGFRβ antibody (WB, 1:2000; cat. 13449-1-AP) and MMP1 Rabbit Polyclonal antibody

(16) Blockade of the estrogen receptor alpha-pregnane X receptor axis protects ovariectomized mice against ethanol-induced hepatotoxicityJournal of Biological ChemistryMay 15, 2025Elizabeth Twum, Malvin Ofosu-Boateng, Daniel O. Nnamani, Lidya H. Gebreyesus, Nour Yadak, Kusum K. Kharbanda, Frank J. Gonzalez, Maxwell A. Gyamfi,Santa Cruz,Sc-271983,1:500 PPARƔ,Santa Cruz,Sc-7273,1:1000 CIDEC (FSP27),Abcam,AB198204,1:1000 EGR1,Cell Signaling,4153S,1:1000 BCL-XL,Cell Signaling,2764S,1:1000 FAS,Cell Signaling,3180S,1:1000 ACC1A,Cell Signaling,3676S,1:1000 CYP3A,Santa Cruz

(17) Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epitheliaSci RepApril 9, 2025Akihito Inoko, Norihito Soga, Minako Suzuki, Tohru Kiyono, Junichi Ikenouchi, Takahiro Kojima, Yoshikatsu Sato, Daisuke Saito, Tatsuo Miyamoto, Naoki Goshima, et al.and (https://www.sigmaaldrich.com/AM/en/product/sigma/hpa003316); anti-EGR1/CAB019427/Cell Signaling #4153 (https://www.cellsignal.com/products/primary-antibodies/egr1-15f7-rabbit-mab/4153). URLs that link to

(18) EGF-upregulated lncRNA ESSENCE promotes colorectal cancer growth through stabilizing CAD and ferroptosis defenceResearch (Wash D C)April 3, 2025Xiaoshan Xie, Boyu Zhang, Jingxuan Peng, Ning Ma, Qihao Pan, Yue Wei, Huililn Jin, Fenghai Yu, Xiaoling Huang, Peng Zhang, et al.for control samples, the remaining chromatin was immunoprecipitated with EGR1 antibody (CST, Cat No. 4153, 1:100) or control rabbit immunoglobulin G in conjunction with ChIP beads at 4 °C overnight. Immunoprecipitated

(19) Podocyte Injury and Long-term Kidney Prognosis in Patients with Lupus NephritisKidney360April 1, 2025Masahiro Okabe, Yusuke Okabayashi, Takaya Sasaki, Kentaro Koike, Nobuo Tsuboi, Taiji Matsusaka, Takashi Yokoothick sections, immunostained with antibodies against EGR1 (Cell Signaling Technology, Danvers, MA, 4153 15F7 clone, 1:50), and counterstained with periodic acid–Schiff stain. EGR1-positive cells on the outer

(20) Stiff extracellular matrix activates the transcription factor ATF5 to promote the proliferation of cancer cellsiScienceMarch 21, 2025Seiichiro Ishihara, Atsushi Enomoto, Akihiro Sakai, Tadashi Iida, Shoichiro Tange, Noriyuki Kioka, Akihiro Nukuda, Ayaka Ichikawa Nagasato, Motoaki Yasuda, Takashi Tokino, et al.incubated with primary antibodies (150,000 Anti-ATF5, Rabbit-Mono(SD2099); 1:3,000 EGR1(15F7) Rabbit mAb, 4153S, Cell Signaling Technology; 1:10,000 Anti-c-Myc-ChIP Grade, ab32072, abcam; or 1:10,0000 β-actin Anti-beta

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3/17/2021Excellent Immunodetection of EGR1 Raj KumarThe mouse cell line was treated with a growth factor examined to test its effect on the steady-state level of EGR1 proteins. For this, growth-arrested mouse cells were treated with the growth factor, ... Read Review

EGR1 (15F7) Rabbit mAb

EGR1 (15F7) Rabbit mAb from Cell Signaling Technology

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EGR1 (15F7) Rabbit mAb from Cell Signaling Technology

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