SEK1 (5C10) Rabbit mAb 3346S from Cell Signaling Technology

Product Specs
ItemSEK1 (5C10) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number3346S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
TargetMKK4
HostRabbit
NCBI Gene AliasesJNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1
ClonalityMonoclonal
NCBI Full Gene Namemitogen-activated protein kinase kinase 4
Research AreaMAP Kinase Signaling
IsotypeIgG
Clone5C10
Molecular Weight44

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Spatiotemporal regulation of MKK4 dictates switch-like JNK activation and binary cell-fate decisionsNature CommunicationsJanuary 8, 2026Hisashi Moriizumi, Takanori Nakamura, Yuji Kubota, Ryosuke Hiranuma, Youngmin Cho, Toru Kawanishi, Hiroyuki Takeda, Takashi Suzuki, Mutsuhiro Takekawaanti-phospho-MAPKAPK2 (Thr334) 27B7 (3007), anti-phospho-PXTP (14378), anti-phospho-PXSP 34B2 (2325), anti-MKK4 5C10 (3346) (Cell Signaling Technology); rabbit polyclonal anti-c-Jun (Santa Cruz Biotechnology, sc-1694); anti-phospho-ERK

(2) Mapping of the contraction-induced phosphoproteome identifies TRIM28 as a significant regulator of skeletal muscle size and functionCell reportsMarch 2, 2021Steinert ND, Potts GK, Wilson GM, Klamen AM, Lin KH, Hermanson JB, McNally RM, Coon JJ, Hornberger TA.RESOURCE,SOURCE,IDENTIFIER Antibodies,, Anti-Rabbit Total SEK1(MKK4) (5C10),"Cell Signaling Technologies (Danvers, MA, USA)",Cat# 3346S; RRID:AB_330905 Anti-Rabbit P-SEK1(MKK4) Ser257 (C36C11),"Cell Signaling Technologies (Danvers, MA,

(3) Responses of sorghum hybrids to germination temperatures and identification of low temperature resistanceActa Agronomica SinicaJune 1, 2020Meng-Ying XIAO, Xiao-Fei CHEN, Rui-Dong ZHANG, Xiao-Xue XU, Rui-Dong HUANG, Xue-Ying AI, Bang LI, Yu-Fei ZHOU, Bing JIANG, Yi-Fan XINGresis- 707723. tance from germination stage to seedling stage in upland cotton. Sci Agric Sin, 2016, 49: 33323346 (in Chinese with English [6] Ma Z, Bykova N V, Igamberdiev A U. Cell signaling mechanisms abstract). and

(4) Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activationNature CommunicationsDecember 1, 2018Jr-Ming Yang, Sayak Bhattacharya, Hoku West-Foyle, Chien-Fu Hung, T.-C. Wu, Pablo A. Iglesias, Chuan-Hsiang Huang

(5) Differential expression of proteins in genetically distinct Trypanosoma cruzi samples (TcI and TcII DTUs) isolated from chronic Chagas disease cardiac patientsParasites & VectorsDecember 1, 2018Maykon Tavares de Oliveira, Karina Taciana Santos Silva, Leandro Xavier Neves, Max Jean de Ornelas Toledo, William Castro-Borges, Marta de Lana

(6) Inhibiting proliferation and migration of lung cancer using small interfering RNA targeting on Aldo-keto reductase family 1 member B10Molecular Medicine ReportsNovember 28, 2017Zhen Zhou, Yi Zhao, Lingping Gu, Xiaoming Niu, Shun Lu

(7) The role of MAP2 kinases and p38 kinase in acute murine liver injury modelsCell Death & DiseaseJune 1, 2017Jun Zhang, Robert W M Min, Khanh Le, Sheng Zhou, Mariam Aghajan, Tin A Than, Sanda Win, Neil Kaplowitzlysate were stored in − 80 °C. Antibodies and reagents. Antisera to P-JNK (#4668), SEK1/MKK4 (5C10; #3346), Phospho-SEK1/MKK4 (Ser257; C36C11; #4514), P-Src(Tyr416; #6943), c-Src (2109), P-p38 (#4511), total

(8) Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migrationOncotargetDecember 13, 2016Farsam V, Basu A, Gatzka M, Treiber N, Schneider LA, Mulaw MA, Lucas T, Kochanek S, Dummer R, Levesque MP, et al.(Cell Signaling, Massachusetts, USA) including p42/44 (#4695, 1:2000 & #4370, 1:2000), SEK1/MKK4 (#3346, 1:1000 & #4514, 1:1000), ATF-2 (#9226, 1:1000 & #5112, 1:1000), c-Jun (#9165 & #2361, 1:1000) and p38

(9) iRhom2 is involved in lipopolysaccharide-induced cardiac injury in vivo and in vitro through regulating inflammation responseBiomedicine & PharmacotherapyNovember 16, 2016Xue-Li Lu, Cui-Hua Zhao, Han Zhang, Xin-Liang Yao

(10) Altered Myokine Secretion Is an Intrinsic Property of Skeletal Muscle in Type 2 DiabetesPloS oneJanuary 1, 2016Ciaraldi TP, Ryan AJ, Mudaliar SR, Henry RR.

(11) Serum- and Glucocorticoid-Inducible Kinase 1 Confers Protection in Cell-Based and in In Vivo Neurotoxin Models via the c-Jun N-Terminal Kinase Signaling PathwayMolecular and Cellular BiologyJune 1, 2015Sarah Iqbal, Shannon Howard, Philip V. LoGrassoCell Signaling Technology): phospho-JNK (catalog number 9255), phospho-c-Jun (3270), Hsp70 (4876), MKK4 (3346), phospho-MKK4 (Ser257/Thr261) (9156), phospho-MKK4 (Ser80) (9155), phospho-MKK7 (4171), phospho-Akt

(12) microRNA-23b regulates the expression of inflammatory factors in vascular endothelial cells during sepsisExperimental and Therapeutic MedicineApril 1, 2015MING WU, JIAN-TENG GU, BIN YI, ZHONG-ZHI TANG, GUO-CAI TAO

(13) Evaluation of efficacy of a new MEK inhibitor, RO4987655, in human tumor xenografts by [(18)F] FDG-PET imaging combined with proteomic approachesEJNMMI researchDecember 1, 2014Tegnebratt T, Ruge E, Bader S, Ishii N, Aida S, Yoshimura Y, Ooi CH, Lu L, Mitsios N, Meresse V, et al.pMKK4 (S257/T261, Cell Signaling Technology, #9156), MKK4 (SEK1(5C10), Cell Signaling Technology, #3346), pAKT (S473, Cell Signaling Technology, 9271), AKT (Cell Signaling Technology, 9272), pERK (T202/Y204,

(14) The Ubiquitin Ligase Nedd4-1 Participates in Denervation-Induced Skeletal Muscle Atrophy in MicePLoS ONEOctober 26, 2012Preena Nagpal, Pamela J. Plant, Judy Correa, Alexandra Bain, Michiko Takeda, Hiroshi Kawabe, Daniela Rotin, James R. Bain, Jane A. E. Battphosphatases regulate endosomal PI(3)P and growth factor receptor trafficking. Mol Biol Cell 19: 3334–3346. E08-04-0367 Lemmon MA, Schlessinger J (2010) Cell signaling by receptor tyrosine kinases. Cell 141:

(15) Malleable Machines in Transcription Regulation: The Mediator ComplexPLoS Computational BiologyDecember 19, 2008Ágnes Tóth-Petróczy, Christopher J. Oldfield, István Simon, Yuichiro Takagi, A. Keith Dunker, Vladimir N. Uversky, Monika FuxreiterThe interplay between structure and function in intrinsically unstructured proteins. FEBS Lett 579: 3346–3354. 38. Iakoucheva L, Brown C, Lawson J, Obradovic Z, Dunker A (2002) Intrinsic Disorder in Cell-signaling

(16) Apoptosis Antagonizing Transcription Factor Protects Renal Tubule Cells against Oxidative Damage and Apoptosis Induced by Ischemia-ReperfusionJournal of the American Society of NephrologyDecember 1, 2006Jun Xie, Qing Guoinduction of AATF 3340 Journal of the American Society of Nephrology J Am Soc Nephrol 17: 3336 –3346, 2006 Cell Signaling Technology, Beverly, MA), and Western blotting was performed by following the

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10/26/2021Great MKK4 Antibody xc lThe antibody identify the endogenous protein of MKK4 well.

SEK1 (5C10) Rabbit mAb

SEK1 (5C10) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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SEK1 (5C10) Rabbit mAb from Cell Signaling Technology

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