p70 S6 Kinase (49D7) Rabbit mAb (Biotinylated) 5707S from Cell Signaling Technology

Product Specs
Itemp70 S6 Kinase (49D7) Rabbit mAb (Biotinylated)
CompanyCell Signaling Technology
Price $450.00 Inquire
Catalog Number5707S
Quantity100 µl
ApplicationsW
ReactivityH, M, R, Mk
Targetp70S6K1
HostRabbit
NCBI Gene AliasesPS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
Conjugate/TagBiotin
ClonalityMonoclonal
NCBI Full Gene Nameribosomal protein S6 kinase B1
Research AreaPI3K / Akt Signaling
IsotypeIgG
Clone49D7
Molecular Weight70, 85

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Assessing the neuroendocrine and psychological effects of acute everolimus administration in healthy male participantsBrain Behav Immun HealthOctober 6, 2025Lucie Jacquet, Anna Lena Friedel, Elisa Orth, Nathalie Reiser, Tina Hörbelt-Grünheidt, Sophie Wiczoreck, Oliver Witzke, Manfred Schedlowski, Marie JakobsBIO-RAD) and stained with pP70S6K-Thr389 (1:1000; Cell Signaling, #9205), P70S6K (1:1000; Cell Signaling, #5707), pAkt-Ser473 (1:1000; Cell Signaling, #9271) and Akt (1:1000; Cell Signaling, #9272) primary antibodies

(2) PI3K-dependent GAB1/Erk phosphorylation renders head and neck squamous cell carcinoma sensitive to PI3Kα inhibitorsCell Death DisJune 18, 2025Xu Zhang, Jiao Xu, Xuan Wang, Lan Xu, Xi Zhang, Yi Wang, Shujuan Jiang, Yixiang Zhang, Jian Ding, Chen Qing, et al.Western blotting was performed with antibodies against Akt (#4691), phospho-Akt (Ser473; #4060), S6K (#5707), phospho-S6K (Thr389; #9205), Erk (#4695), phospho-Erk (Thr185/Tyr187; #4370), GAB1 (#93804), phospho-GAB1

(3) A CRISPR-edited isoform of the AMPK kinase LKB1 improves the response to cisplatin in A549 lung cancer cellsJournal of Biological ChemistryFebruary 13, 2025Matheus Brandemarte Severino, Ana Paula Morelli, Isadora Carolina Betim Pavan, Mariana Camargo Silva Mancini, Mariana Marcela Góis, Rafael Junqueira Borges, Renata Rosseto Braga, Luiz Guilherme Salvino da Silva, Nathalia Quintero-Ruiz, Maíra Maftoum Costa, et al.(Cell signaling #2775), S6 (Cell signaling #2317), pS6 (Cell signaling #9234), S6K1 (Cell signaling #5707), pS6K1 (Cell signaling #9234), S6K2 (Cell signaling #14130), pS6K2 (Invitrogen #PA5-105036), mTOR (Cell signaling

(4) Quantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core networkPLOS Computational BiologyOctober 1, 2024Bertram Klinger, Isabel Rausch, Anja Sieber, Helmut Kutz, Vanessa Kruse, Marieluise Kirchner, Philipp Mertins, Arnd Kieser, Nils Blüthgen, Dieter Kubeα-p-p42/44 (#4370), rabbit α-p-p42/44 (#4377), rabbit α-p-MEK1/2 (#9154), rabbit α-p70 S6 Kinase (49D7) (#5707), rabbit α-p-p70 S6 KinaseThr389 (108D2)(#9234), α-p-Raf1Ser289/296/301(#9431), rabbit α-p-Raf1Ser338

(5) DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairmentElifeSeptember 10, 2024Ran-Der Hwang, YuNing Lu, Qing Tang, Goran Periz, Giho Park, Xiangning Li, Qiwang Xiang, Yang Liu, Tao Zhang, Jiou WangCell Signaling); anti-mTOR (2983, Cell Signaling); anti-mTOR (Ser2448) (5536, Cell Signaling); anti-P70S6K (5707, Cell Signaling); anti-P70S6K (Thr389) (9205, Cell Signaling); anti-TDP-43 (10782–2-AP, ProteinTech);

(6) COX6C expression driven by copy amplification of 8q22.2 regulates cell proliferation via mediation of mitosis by ROS-AMPK signaling in lung adenocarcinomaCell Death & DiseaseJanuary 19, 2024Shuanghui Liu, Fanggui Shao, Yourong Wang, Yurui Zhang, Hongjia Yu, Ningxin Zhang, Lan He, Qingran Kong, Hao Jiang, Zhixiong Donganti-phospho-Aurora A antibody (3079), rabbit anti-phospho-P70 antibody (97596), rabbit anti-P70 antibody (5707), rabbit anti-phospho-AMPK antibody (2535) and rabbit anti-AMPK antibody (5831) were purchased from

(7) Proteogenomics of clear cell renal cell carcinoma response to tyrosine kinase inhibitorNature communicationsJuly 17, 2023Zhang H, Bai L, Wu XQ, Tian X, Feng J, Wu X, Shi GH, Pei X, Lyu J, Yang G, et al.MDH2 (#A13516, 1:1000), CALU (#A6538, 1:1000) were purchased from Abclonal. Antibodies against S6K (#5707, 1:1000) and pS6K (#9209, 1:1000) were purchased from Cell Signaling Technology. Antibody against VHL

(8) Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storageThe Journal of biological chemistryJuly 1, 2021Ilnytska O, Lai K, Gorshkov K, Schultz ML, Tran BN, Jeziorek M, Kunkel TJ, Azaria RD, McLoughlin HS, Waghalter M, et al.(Cell Signaling Technology, #97596), Rabbit monoclonal p70 S6 Kinase (49D7) (Cell Signaling Technology, #5707), Rabbit monoclonal Phospho-mTOR (Ser2448) (D9C2) (Cell Signaling Technology, #5536), Anti-Human SMPD1

(9) Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formationJournal of neuroinflammationJanuary 11, 2020Ye X, Zhu M, Che X, Wang H, Liang XJ, Wu C, Xue X, Yang J.anti-MTOR (1:1000; CST, 2972 s), anti-p-MTOR (Ser2448) (1:1000; CST, 2971 s), anti-p70S6K (1:1000; CST, 5707 s), anti-p-p70S6K (Thr389) (1:1000; CST, 9234 s); anti-Beclin-1 (1:1000; CST, 3495 s), anti- SQSTM1

(10) Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosisPloS oneJanuary 1, 2018Korfei M, Stelmaszek D, MacKenzie B, Skwarna S, Chillappagari S, Bach AC, Ruppert C, Saito S, Mahavadi P, Klepetko W, et al.X, Levy DE. Cell signaling. Stat acetylation—a key facet of cytokine signaling? Science. 2005; 307(5707):217–8. https://doi.org/10.1126/science.1108164 PMID: 15653493 76. Wieczorek M, Ginter T, Brand P,

(11) Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265P mutationsJCI InsightMarch 30, 2017Patrizia Mondello et al.X, Levy DE. Cell signaling. Stat acetylation--a key facet of cytokine signaling? Science. 2005;307(5707):217–218. 14. Gupta M, Han JJ, Stenson M, Wellik L, Witzig TE. Regulation of STAT3 by histone deacetylase-3

(12) Bufalin reverses intrinsic and acquired drug resistance to cisplatin through the AKT signaling pathway in gastric cancer cellsMolecular medicine reportsAugust 1, 2016Zhao H, Zhao D, Jin H, Li H, Yang X, Zhuang L, Liu T.1:1,000), phosphorylated 4EBP1 (P‑4EBP1; Ser65; #9451; 1:1,000), ribosomal protein S6 kinase (S6K; #5707; 1:1,000) and phosphorylated S6K (p‑S6K; Thr389; #9206; 1:1,000) were obtained from Cell Signaling Technology,

(13) Protective Macroautophagy Is Involved in Vitamin E Succinate Effects on Human Gastric Carcinoma Cell Line SGC-7901 by Inhibiting mTOR Axis PhosphorylationPLOS ONEJuly 13, 2015Liying Hou, Yuze Li, Huacui Song, Zhihong Zhang, Yanpei Sun, Xuguang Zhang, Kun Wu(Cell Signaling, 2972S), rabbit anti-p-mTOR (Ser2448) (Cell Signaling,5536S), rabbit anti-p70S6K (Cell Signaling,5707S), rabbit anti-p-p70S6K (T389) (Cell Signaling, 9205S), rabbit anti-4E-BP-1 (Cell Signaling, 8594S),

(14) Impact of WIN site inhibitor on the WDR5 interactomeCell reportsJanuary 1, 0001"Guarnaccia AD, Rose KL, Wang J, Zhao B, Popay TM, Wang CE, Guerrazzi K, Hill S, Woodley CM, Hansen TJ, et al.",Cell Signaling Technology,Cat# 4060; RRID:AB_2797780 Rabbit monoclonal anti-p70 S6 Kinase (49D7),Cell Signaling Technology,Cat# 5707; RRID:AB_10694087 Rabbit polyclonal anti-phospho-p70 S6 Kinase (Thr389),Cell Signaling Technology,Cat#

Be the First to Write a Review!

p70 S6 Kinase (49D7) Rabbit mAb (Biotinylated)

p70 S6 Kinase (49D7) Rabbit mAb (Biotinylated) from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (14)

Reviews

p70 S6 Kinase (49D7) Rabbit mAb (Biotinylated) from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map