Lck (73A5) Rabbit mAb 2787S from Cell Signaling Technology

Product Specs
ItemLck (73A5) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number2787S
Quantity100 µl
ApplicationsW
ReactivityH
TargetLck
HostRabbit
NCBI Gene AliasesIMD22, LSK, YT16, p56lck, pp58lck
ClonalityMonoclonal
NCBI Full Gene NameLCK proto-oncogene, Src family tyrosine kinase
ModificationsLck (Tyr505) phosphate
Research AreaImmunology and Inflammation
Clone73A5
Molecular Weight56 KDa

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Tankyrases positively regulate influenza A virus replication via type I interferon responseJ VirolOctober 23, 2025Gayan Bamunuarachchi, Kishore Vaddadi, Yurong Liang, Zhengyu Zhu, Quanjin Dang, Sankha Hewawasam, Lin LiuBethyl Laboratories, TX, USA), rabbit anti-TNKS2 (1:1000, ab-155545, Abcam, Cambridge, UK), rabbit anti-Axin1 (1:1000, 2787S, Cell Signaling, Denver, MA, USA), mouse anti-NP (1:50, HB-65, ATCC), mouse anti-NS1 (1:1000, sc-130568,

(2) Chimeric antigen receptor with novel intracellular modules improves antitumor performance of T cellsSignal Transduct Target TherJanuary 15, 2025Pengju Wang, Yiyi Wang, Xiaojuan Zhao, Rui Zheng, Yiting Zhang, Ruotong Meng, Hao Dong, Sixin Liang, Xinyi He, Yang Song, et al.Blotting was performed under denatured conditions using the following antibodies: anti-LCK (CST, Cat. #2787 T), anti-ZAP70 (CST, Cat. #3165 T), anti-LAT (CST, Cat. #45533S), anti-ERK1/2 (Proteintech, Cat. #11257-1-AP),

(3) CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling AxisCancer discoveryOctober 4, 2024Acharya S, Basar R, Daher M, Rafei H, Li P, Uprety N, Ensley E, Shanley M, Kumar B, Banerjee PP, et al.(Abcam, EP265(2)Y, Cat# ab68235), total CD3Z (Bethyl Laboratories, Cat# A305–212A), Lck (CST, 73A5, Cat# 2787), pZAP70 Tyr319/Syk Tyr352 (CST, Cat# 2701), ZAP70 (CST, D1C10E, Cat# 3165), CD28 (CST, D2Z4E, Cat#

(4) Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomasCancer CellMay 13, 2024Jaewoo Choi, Michele Ceribelli, James D. Phelan, Björn Häupl, Da Wei Huang, George W. Wright, Tony Hsiao, Vivian Morris, Francesco Ciccarese, Boya Wang, et al.RRID:AB_2274754 FYN,Cell Signaling Technology,Cat.# 4023; RRID:AB_10698604 LCK,Cell Signaling Technology,Cat.# 2787; RRID:AB_659970 SRC,Cell Signaling Technology,Cat.# 2109; RRID:AB_2106059 FGR,Cell Signaling Technology,Cat.#

(5) Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specifiedNature communicationsJune 17, 2021Debackere K, Marcelis L, Demeyer S, Vanden Bempt M, Mentens N, Gielen O, Jacobs K, Broux M, Verhoef G, Michaux L, et al.and CD3E staining, cells were incubated over night at 4 °C with anti-LCK antibody (Cell Signaling, #2787S) diluted 1:200 and anti-CD3E antibody (BioLegend, #100223) diluted 1:500 in staining buffer. After washing,

(6) Cell signaling pathways in autosomal-dominant leukodystrophy (ADLD): the intriguing role of the astrocytesCellular and molecular life sciences : CMLSMarch 1, 2021Ratti S, Rusciano I, Mongiorgi S, Owusu Obeng E, Cappellini A, Teti G, Falconi M, Talozzi L, Capellari S, Bartoletti-Stella A, et al.LIF-R Cell signaling pathways in autosomal-dominant leukodystrophy (ADLD): the intriguing role… 2787 Fig. 2 Lamin B1 accumulation reduces LIF and LIF-R expression. LIF and LIF-Receptor expression were

(7) Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer cachexiaCell death & diseaseJanuary 28, 2021Hu W, Xiong H, Ru Z, Zhao Y, Zhou Y, Xie K, Xiao W, Xiong Z, Wang C, Yuan C, et al.number ab18207), CD9 (catalog number ab92726), TSG101 (catalog number 125011), and Hsp70 (catalog number 2787) from Abcam; and an antibody against Rab27A from Proteintech (Wuhan, China). We performed quantitative

(8) Regulation of T cell receptor signaling by protein acyltransferase DHHC21Molecular biology reportsAugust 1, 2020Fan Y, Shayahati B, Tewari R, Boehning D, Akimzhanov AM.procedures Antibodies and reagents The following antibodies were purchased from Cell Signaling: Lck (Cat. 2787), pSrc (Cat. 2101), pZAP70 (Cat. 2717), ZAP70(Cat. 3165), pErk1/2 (Cat. 4370), Erk1/2 (Cat. 4376). DHHC21

(9) Differential Targeting of Gr-MDSCs, T Cells and Prostate Cancer Cells by Dactolisib and DasatinibInternational journal of molecular sciencesMarch 27, 2020Liu G, Jin Z, Lu X.phospho-Src Tyr527 (CST 2105), p38 MAPK (CST 9212), phospho-P38 MAPK Thr180/182 (CST 4511), Lck (CST 2787), phospho-Lck Tyr394 (Thermo Fisher, PA5-37628, Waltham, MA, USA), phospho-Lck Tyr505 (CST 2751), CD3ε

(10) Role of Immunotherapy for Oncogene-Driven Non-Small Cell Lung CancerCancers (Basel)July 27, 2018Yosuke Miura, Noriaki Sunaga(mut.),1.67 [0.64–4.34],NS "Zhang, et al. [88] (meta-analysis)",IHC,Various,Various,EGFR,1560 vs. 2787,30% vs. 34%,0.61 [0.42–0.90],0.01 "Zhang, et al. [88] (meta-analysis)",IHC,Various,Various,ALK,69 vs.

(11) Healing of Preterm Ruptured Fetal MembranesScientific reportsOctober 13, 2017Mogami H, Hari Kishore A, Akgul Y, Word RA.

(12) CONSECUENCIAS JURÍDICO LABORALES DE LA EMPRESA USUARIA, EN LA DECLARATORIA DE EXISTENCIA DEL CONTRATO REALIDADLegemFebruary 1, 2016Carlos Antonio MUSKUS OTEROdeclaratoria de existencia del contrato realidad. MUSKUS OTERO, Carlos Antonio, pp. 21-33 ISSN: 2346-2787 / Vol. 3, Núm. 1 / Julio - Diciembre 2015 Algo similar comentó el tratadista GERMÁN 7 No sobra recordar

(13) PP6 Controls T Cell Development and Homeostasis by Negatively Regulating Distal TCR SignalingThe Journal of ImmunologyFebruary 15, 2015Jian Ye et al.p-IkBε (4924), IkBε (9249), p-Zap70 (2717), Zap70 (3165), p-LAT (3584), LAT (9166), p-LCK (2751), LCK (2787), p-PLCg1 (2821), and PLCg1 (5690) purchased from Cell Signaling. Anti-PP6 (07-1224) was from Millipore,

(14) Effective Therapeutic Approach for Head and Neck Cancer by an Engineered Minibody Targeting the EGFR ReceptorPLoS ONEDecember 1, 2014Young Pil Kim et al.epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol 21: 2787–2799. 2. Lemmon MA, Schlessinger J (2010) Cell signaling by receptor tyrosine kinases. Cell 141: 1117–1134. 3.

(15) Retrograde labeling, transduction, and genetic targeting allow cellular analysis of corticospinal motor neurons: implications in health and diseaseFrontiers in NeuroanatomyMarch 26, 2014Javier H. Jara, BarÃ„Â±Ã…Å¸ GenÃƒÂ§, Jodi L. Klessner, P. Hande Ãƒâ€“zdinlerCSMN spinal motor neurons in an ALS mouse model. J. Neurosci. 33, 7890–7904. doi: 10.1523/JNEUROSCI.2787-12.2013 Yorke, C. H. Jr., and Caviness, V. S. Jr. (1975). Interhemispheric neocortical connections of

(16) Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytesBloodOctober 10, 2013Jason A. Dubovsky et al.described7. Blotting was conducted using pZAP70 #2717, ZAP70 #3165, pLAT #3584, LAT #9166, pLCK #2751, LCK #2787, pSTAT1 #9177S, STAT1 #9176, NFAT1 #4389S, pITK #3531S, ITK #2380S, JUNB #3746S, pIKBα #9246L, pSTAT6

(17) Molecular Imaging of Hepatocellular Carcinoma Xenografts with Epidermal Growth Factor Receptor Targeted Affibody ProbesBioMed Research InternationalApril 21, 2013Ping Zhao, Xiaoyang Yang, Shibo Qi, Hongguang Liu, Han Jiang, Susan Hoppmann, Qizhen Cao, Mei-Sze Chua, Samuel K. So, Zhen Chengantagonists in the biology and treatment of cancer,” Journal of Clinical Oncology, vol. 21, no. 14, pp. 2787–2799, 2003. J. Schlessinger, "Cell signaling by receptor tyrosine kinases,” Cell, vol. 103, no. 2, pp.

(18) Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cellsOncogeneSeptember 2, 2010Y Gan, C Shi, L Inge, M Hibner, J Balducci, Y Huangepidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol 21: 2787–2799. Moreno-Bueno G, Portillo F, Cano A. (2008). Transcriptional regulation of cell polarity in EMT

(19) Role of cAMP response element binding protein in cardiovascular remodeling: good, bad, or both?Arteriosclerosis, Thrombosis, and Vascular BiologyMarch 1, 2006Toshihiro Ichikic-fos transcriptional activation require distinct upstream regulatory sequences. Mol Cell Biol. 1988;8:2787–2796. 11. Johannessen M, Delghandi MP, Moens U. What turns CREB on? Cell Signalling. 2004;16:1211–1227. 12.

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Lck (73A5) Rabbit mAb

Lck (73A5) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Lck (73A5) Rabbit mAb from Cell Signaling Technology

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