Phospho-IRS-1 (Ser318) (D51C3) Rabbit mAb 5610S from Cell Signaling Technology

Product Specs
ItemPhospho-IRS-1 (Ser318) (D51C3) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number5610S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M
TargetIRS-1 (Ser323) phosphate
ModificationsIRS-1 (Ser323) phosphate
HostRabbit
NCBI Gene AliasesHIRS-1
ClonalityMonoclonal
NCBI Full Gene Nameinsulin receptor substrate 1
Research AreaMetabolism
IsotypeIgG
CloneD51C3
Molecular Weight180

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Revealing the biochemical regulations of L-PGDS in hepatic insulin-resistance using HepG2 cellsProstaglandins & Other Lipid MediatorsJanuary 1, 2026Rhema Khairnar, Md Asrarul Islam, Kuljeet Singh, Divya K. Shetty, Anjali Yadav, Vikas V. Dukhande, Sunil KumarCat#182141), (Phospho-IRS1 (Tyr612), Invitrogen, Cat#44–816G, (Phospho-IRS1 (Ser318), Cell signaling, Cat#5610), (IRS-1, Cell signaling, Cat#2382), (SCAP, Abcam, Cat#308060), (PCSK9, Invitrogen, Cat#MA5–32843),

(2) A genome-wide, CRISPR-based screen reveals new requirements for translation initiation and ubiquitination in driving adipogenic fate changeGenes & DevelopmentOctober 1, 2025Rachel E. Turn, Keren I. Hilgendorf, Carl T. Johnson, Kyuho Han, Mohammad Ovais Aziz-Zanjani, Samuel Swails Bollinger, Pablo Domizi, Ran Cheng, Atefeh Rabiee, Yingdi Zhu, et al.800 nm. The antibodies used were as follows: pIRS1 (1:1000; Cell Signaling Technology 2381, 3203, and 5610), pAKT (1:1000; Cell Signaling Technology 4051), and Tubulin (1:5000; Sigma- 9026). Immunofluorescence

(3) mTORC1 hampers Hedgehog signaling in Tsc2 deficient cellsLife Science AllianceNovember 1, 2024Lasse Jonsgaard Larsen, Elsebet Østergaard, Lisbeth Birk MøllerS235/236 ribosomal protein (1:1,000, # 4858; Cell Signaling), rabbit anti-S6 ribosomal protein (1:1,000, #5610; Cell Signaling), mouse anti-acetylated α-tubulin (1:2,000, #T6793; Sigma-Aldrich), rabbit anti-Smoothened

(4) Defective Visceral Adipose Tissue Adaptation in Gestational Diabetes MellitusThe Journal of Clinical Endocrinology & MetabolismApril 19, 2024Colm J McElwain, Samprikta Manna, Andrea Musumeci, Isaac Sylvester, Chloé Rouchon, Anne Marie O'Callaghan, Mustafa Abdalla Bakhit Ebad, Fergus P McCarthy, Cathal M McCarthyphospho-IRS1(ser312) 1:1000 (Cell Signaling #2381, RRID:AB_330342); phospho-IRS1(ser323) 1:1000 (Cell Signaling #5610, RRID:AB_10695244); phospho-IRS1(ser616) 1:1000 (Cell Signaling #3203, RRID:AB_1031167); PDK1 1:1000

(5) Functional characterization and potential therapeutic avenues for variants in the NTRK2 gene causing developmental and epileptic encephalopathiesAmerican Journal of Medical Genetics Part B: Neuropsychiatric GeneticsJanuary 1, 2022Ashlee Long, Andrew Crouse, Robert A. Kesterson, Matthew Might, Deeann Wallisdetected with the anti-P-S6 ribosomal protein (S240/244) antibody and the anti-S6 ribosomal protein (5610) antibody (ref. 2215S; Cell Signaling Technology: ref. 2217S; Cell Signaling Technology). Tubulin was

(6) Hepatocyte-specific PKCβ deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosisMolecular metabolismFebruary 1, 2021Shu Y, Hassan F, Coppola V, Baskin KK, Han X, Mehta NK, Ostrowski MC, Mehta KD.P-insulin receptor/IGF1R beta (#3021), P-IRS-1Ser307 (#2381), P-IRS-1Ser612 (#3203), P-IRS1Ser318 (#5610), IRS-2 (#4502), P-mTORSer2448 (#5536), P-mTORSer2481 (#2974), mTOR (#2983), rictor (#2114), and GβL

(7) Lateral line placodes of aquatic vertebrates are evolutionarily conserved in mammalsBiology openJune 19, 2018Washausen S, Knabe W.

(8) Cancer stem cells from peritumoral tissue of glioblastoma multiforme: the possible missing link between tumor development and progressionOncotargetJune 15, 2018Angelucci C, D'Alessio A, Lama G, Binda E, Mangiola A, Vescovi AL, Proietti G, Masuelli L, Bei R, Fazi B, et al.

(9) CKS Proteins Promote Checkpoint Recovery by Stimulating Phosphorylation of TreslinMolecular and Cellular BiologyOctober 15, 2017Ruiling Mu, John Tat, Robert Zamudio, Yaoyang Zhang, John R. Yates, Akiko Kumagai, William G. Dunphy, Steven I. ReedBethyl Laboratories), glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (3781; ProSci), and ribosomal protein S6 (5610; Cell Signaling Technology). For Western blotting, all antibodies were used at 1:1,000. Horseradish

(10) SYNTHESIS OF BIODIESEL FROM KAPUK SEED OIL (Ceiba Pentandra L) AT VARIATION STIRRING DURATION IN TRANSESTERIFICATION PROCESSJurnal Sains DasarMay 20, 2016Endang Dwi Siswani, Susila Kristianingrum, Tohari TohariNilai viskositas biodiesel BP ; BQ ; BR dan BS berturut-turut sebesar 8,9597, 10,0615; 13,4953dan 15,5610 cSt. Nilai titik tuang pada biodiesel BP , BQ , BR dan BS berturut- turut adalah: -9; -6; -3 dan 36

(11) Fixed single-cell transcriptomic characterization of human radial glial diversityNature methodsJanuary 1, 2016Thomsen ER, Mich JK, Yao Z, Hodge RD, Doyle AM, Jang S, Shehata SI, Nelson AM, Shapovalova NV, Levi BP, et al.

(12) Glioma Cells in the Tumor Periphery Have a Stem Cell PhenotypePloS oneJanuary 1, 2016Munthe S, Petterson SA, Dahlrot RH, Poulsen FR, Hansen S, Kristensen BW.

(13) Overexpression of CD97 confers an invasive phenotype in glioblastoma cells and is associated with decreased survival of glioblastoma patientsPloS oneJanuary 1, 2013Michael Safaee, Aaron J Clark, Michael C Oh, Michael E Ivan, Orin Bloch, Gurvinder Kaur, Matthew Z Sun, Joseph M Kim, Taemin Oh, Mitchel S Berger, Andrew T ParsaCells were counted using the AMG EVOS XL microscope. 5 Cell lysates were generated by transferring 5610 cells to a 10 cm plate and observing them until they reached 75–80% confluence. Plates were washed with

(14) Differential gene expression in abdomens of the malaria vector mosquito, Anopheles gambiae, after sugar feeding, blood feeding and Plasmodium berghei infectionBMC GenomicsDecember 1, 2006Ali N Dana, Maureen E Hillenmeyer, Neil F Lobo, Marcia K Kern, Patricia A Romans, Frank H Collinsgambiae. Proceedings of the National Academy of Sciences of the United States of America 1999, 96(10):5610-5615. Carraway KL, Ramsauer VP, Haq B, Carrothers Carraway CA: Cell signaling through membrane mucins. Bioessays

(15) Identification of an ataxia telangiectasia-mutated protein mediated surveillance system to regulate Bcl-2 overexpressionOncogeneSeptember 14, 2006J Zhang, J M Lahti, A Bruce, L He, K Parihar, C Fan, J Grenet, L Liu, V J Kidd, S Cormier, et al.phosphorylated Chk2 (Cell Signalling, 1:50), and Oncogene Bcl-2 activates ATM in MCF-7 cells J Zhang et al 5610 anti-gH2AX (Upstate, Lake Placid, NY, USA) were then added to the slides at 41C overnight. After washing,

(16) Multiomics analyses reveal dynamic bioenergetic pathways and functional remodeling of the heart during intermittent fastingeLifeJanuary 1, 0001"Arumugam TV, Alli-Shaik A, Liehn EA, Selvaraji S, Poh L, Rajeev V, Cho Y, Cho Y, Kim J, Kim J, et al."Biotechnology), AKT (9272 S, Cell Signaling), Insulin receptor β (3025 S, Cell Signaling), Phospho-IRS1 (Ser318) (5610, Cell Signaling), IRS-1 (2382 S, Cell Signaling), and GAPDH (2118 S, Cell Signaling; NB300-221, Novus Biologicals

(17) Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancyNature immunologyJanuary 1, 0001"Swamy M, Pathak S, Grzes KM, Damerow S, Sinclair LV, van Aalten DM, Cantrell DA."#9402), pY694 STAT5 (1:2000, #9351), pan STAT5 (1:1000, #9363), pT389 S6K (1:1000, #9239), S6K (1:1000, #5610) (Cell Signalling Technology), SMC1 (1:5000, A300-055A, Bethyl), β–tubulin (1:5000, H-235) (Santa Cruz),

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Phospho-IRS-1 (Ser318) (D51C3) Rabbit mAb

Phospho-IRS-1 (Ser318) (D51C3) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (17)

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Phospho-IRS-1 (Ser318) (D51C3) Rabbit mAb from Cell Signaling Technology

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