TRAF1 (45D3) Rabbit mAb 4715S from Cell Signaling Technology

Product Specs
ItemTRAF1 (45D3) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number4715S
Quantity100 µl
ApplicationsW, IP, IHC-P, IF-IC, FC-FP
ReactivityH
TargetTRAF1
HostRabbit
NCBI Gene AliasesEBI6, MGC:10353
ClonalityMonoclonal
NCBI Full Gene NameTNF receptor associated factor 1
Research AreaApoptosis
Clone45D3
Molecular Weight50

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) A simple and broadly applicable nanobody-based approach to generate potent TNFR agonistsCell Death & DiseaseMay 30, 2026Isabell Lang, Olena Zaitseva, Amelie Glöckler, Daniela Siegmund, Dalia Sheta, Bayan Mouhandes, Daniela Weisenberger, Viktoria Schäfer, Svetlana Stepanzow, Theresa Schneider, et al.anti-Caspase-3 (#14220), anti-Caspase-9 (Cell Signaling, MA, USA, #9503), anti-TRAF1 (Cell Signaling, MA, USA, #4715), anti-CD95 (Cell Signaling, MA, USA, #8023), anti-PARP (BD Biosciences, NJ, USA, #556494), anti-Caspase8

(2) CRISPR Screens Reveal Epstein-Barr Virus-activated JunB as a Key Lymphoblastoid B cell Dependency Factor that Represses Cyclin Dependent Kinase Inhibitor P18INK4cbioRxivApril 1, 2026Eric M. Burton, Yifei Liao, Davide Maestri, Bidisha Mitra, Benjamin E. Gewurz(Santa Cruz Biotechnology, SC-40), p100/p52 (EMD Millipore, 05-361), TRAF1 (Cell Signaling Biotechnology, #4715S), HA tag antibody (Cell Signaling Technology, # 3724), BIM (Cell Signaling Biotechnology, #2933), CCND2

(3) Epstein-Barr Virus Latent Membrane Protein 1 Suppresses Ferroptosis via Pentose Phosphate Pathway and Glutathione MetabolismbioRxivMarch 13, 2026Eric M. Burton, Bidisha Mitra, Rui Guo, John M. Asara, Benjamin E. GewurzDDX1 (Bethyl, A300–521A-M), p100/p52 (EMD Millipore, 05–361), TRAF1 (Cell Signaling Biotechnology, #4715S), HA tag antibody (Cell Signaling Technology, #3724). The following reagents were utilized in this study

(4) The nucleardatapy toolkit for simple access to experimental nuclear data, astrophysical observations, and theoretical predictionsEur Phys J A Hadron NuclFebruary 2, 2026Jérôme Margueron, Christian Drischler, Mariana Dutra, Stefano Gandolfi, Alexandros Gezerlis, Guilherme Grams, Sébastien Guillot, Rohit Kumar, Sudhanva Lalit, Odilon Lourenço, et al.spectroscopy obtained in Ref. [230]. source=‘J0437-4715’. Observed mass and radii for source J0437-4715 obtained from different analyses of the observational data (obs=1), see Table 10 for more details. obs=

(5) Helicobacter pylori VacA modulates TRAF1-mediated 4-1BB/NF-kappaB axis to induce host apoptosis and chronic inflammatory damageMol MedOctober 24, 2025Lingzhi Yuan, Shuoyi Yao, Nanfang Qu, Xinmeng Li, Xueer Yang, Aojian Deng, Minglin Zhang, Ting Cai, Lunxi Liang, Zhitao Liu, et al.Cell Signaling Technology, CST), anti-p-P65 (1:500, 3033S, CST), anti-P65 (1:1000, 4764, CST), anti-TRAF1 (1:500, 4715, CST), anti-4-1BB (1:100, ab203391, Abcam), anti-Caspase-9 (1:500,9508,CST), anti-Caspase-3 (1:500,

(6) Epstein-Barr virus latent membrane protein 1 subverts IMPDH pathways to drive B-cell oncometabolismPLOS PathogensMay 14, 2025Eric M. Burton, Davide Maestri, Shaowen White, Jin-Hua Liang, Bidisha Mitra, John M. Asara, Benjamin E. Gewurz(Santa Cruz Biotechnology, SC-40), p100/p52 (EMD Millipore, 05-361), TRAF1 (Cell Signaling Biotechnology, #4715S), HA tag antibody (Cell Signaling Technology, # 3724), Fas-APC (Biolegend, 305612), ICAM-1-PE (BD Bioscience,

(7) Ubiquitination of gasdermin D N-terminal domain directs its membrane translocation and pore formation during pyroptosisCell Death DisMarch 17, 2025Xiufeng Chu, Ting Zhang, Ihtisham Bukhari, Mei Hu, Jixuan Xu, Yamin Xing, Xinfeng Liang, Zisen Zhang, Pengyuan ZhengHuman Reactive Cell Death and Autophagy Antibody Sampler Kit (#42867, 1:1000), the Mouse Reactive Pyroptosis Antibody Sampler Kit (#98303, 1:1000), TRAF1 (#4715, 1:1000), OTUB1 (#3783, 1:1000), and LSD1 (#2184, 1:1000) were purchased from Cell Signaling Technology.

(8) Genetically engineered IgG1 and nanobody oligomers acquire strong intrinsic CD40 agonismBioengineeredDecember 31, 2024Nienke Hesen, Mohamed Anany, Andre Freidel, Mediya Baker, Daniela Siegmund, Olena Zaitseva, Harald Wajant, Isabell Langmembrane western blot analysis was performed with an anti-p100/p52 (#05–361, Millipore), anti-TRAF1 (#4715), anti-A20 (#5630, both Cell Signaling Technology Beverly, MA, USA), anti-β-actin (#A1978–200), anti-Flag

(9) Characterization of target gene regulation by the two Epstein-Barr virus oncogene LMP1 domains essential for B-cell transformationmBioNovember 27, 2023Bidisha Mitra, Nina Rose Beri, Rui Guo, Eric M. Burton, Laura A. Murray-Nerger, Benjamin E. Gewurzhas previously been reported (27). Antibodies and reagents Cell Signaling Technology (CST) TRAF1 (#4715, rabbit mAb), p105/50 (#3035, rabbit mAb), RelA (#8242, rabbit mAb), phospho-RelA (Ser536) (3033, rabbit

(10) Elabela inhibits TRAF1/NF-κB induced oxidative DNA damage to promote diabetic foot ulcer wound healingiScienceSeptember 15, 2023Yinghui Hong, Jun Li, Yinsheng Zhong, Shujun Yang, Liying Pei, Zijie Huang, Xuxiang Chen, Hao Wu, Guanghui Zheng, Chaotao Zeng, et al.,Cell Signaling Technology,"Cat# 8242, RRID:AB_10859369" rabbit anti-TRAF1,Cell Signaling Technology,"Cat# 4715, RRID:AB_2303912" rabbit anti-phospho-IκBα,Cell Signaling Technology,"Cat# 2859, RRID:AB_561111" mouse

(11) DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon CancerCancer researchJune 2, 2023Miller AL, Perurena N, Gardner A, Hinoue T, Loi P, Laird PW, Cichowski K.(Cell Signaling Technology, catalog no. 4223, RRID:AB_1903909) 1:1,000, TRAF1 (Cell Signaling Technology, catalog no. 4715, RRID:AB_2303912) 1:1,000, TRAF2 (Cell Signaling Technology, catalog no. 4724, RRID:AB_2209845) 1:1,000,

(12) Characterization of Target Gene Regulation by the Two Epstein-Barr Virus Oncogene LMP1 Domains Essential for B-cell TransformationbioRxivApril 13, 2023Bidisha Mitra, Rui Guo, Eric M. Burton, Laura A. Murray-Nerger, Benjamin E. Gewurzhas previously been reported (27). Antibodies and Reagents. Cell Signaling Technology (CST) TRAF1 (#4715, Rabbit mAb), p105/50 (#3035, Rabbit mAb), RelA (#8242, Rabbit mAb), phospho-RelA (Ser536) (3033, Rabbit

(13) A TNFR2-Specific TNF Fusion Protein With Improved In Vivo ActivityFrontiers in ImmunologyJune 13, 2022Juan Gamboa Vargas et al.used were purchased from Cell Signaling Technology Beverly, MA, USA: anti-p100/p52 (#4882), TRAF1 (#4715), TRAF2 (#4724), anti-rat IgG HRP-linked antibody (#7077) and anti-rabbit IgG, HRP-linked antibody (#7074).

(14) Anti-Fn14 Antibody-Conjugated Nanoparticles Display Membrane TWEAK-Like Agonism †PharmaceuticsJuly 13, 2021Ahmed Aido, Olena Zaitseva, Harald Wajant, Matej Buzgo, Aiva Simaiteinterest were detected via sequential incubation with primary antibodies: (anti-TRAF1 mAb, (45D3) #4715, Source: Rabbit; anti-TRAF2 mAb, Source: Rabbit, (C192), #4724) from Cell Signaling, MA, USA; anti-NFκB

(15) Polyphyllin I suppresses proliferation and promotes apoptosis of gastric cancer cell by inhibiting stat3 phosphorylationTranslational cancer researchAugust 1, 2020Han J, Kan J, Wang X, Yuan Q, Song X, Huang M, Wu H.(Cell Signaling Technology, Inc.; 9145), STAT3 (Cell Signaling Technology, Transl Cancer Res 2020;9(8):4715-4725 | http://dx.doi.org/10.21037/tcr-20-66 Translational Cancer Research, Vol 9, No 8 August 2020 4717 Inc.;

(16) Coulomb pre-stress and fault bends are ignored yet vital factors for earthquake triggering and hazardNature CommunicationsDecember 1, 2019Z. K. Mildon, G. P. Roberts, J. P. Faure Walker, S. TodaCoulomb stress transferred (bars) i 370 4760 320 4710 350 4660 370 4765 k l > 1.0 370 4765 320 4715 Source fault Surface fault trace < –0.5 Difference in Coulomb stress transferred (bars) > 0.5 Fig.

(17) Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survivalPLoS pathogensSeptember 1, 2019Wang LW, Wang Z, Ersing I, Nobre L, Guo R, Jiang S, Trudeau S, Zhao B, Weekes MP, Gewurz BE.(Santa Cruz, Cat#517224), phospho-mTOR (Ser2448) (Cell Signaling, Cat#2971), TRAF1 (Cell Signaling, Cat#4715), GAPDH (Abcam, Cat#8245), α-tubulin (Abcam, Cat#7291), horse anti-mouse IgG HRP-linked antibody (Cell Signaling,

(18) Functional and Mechanistic Interrogation of BET Bromodomain Degraders for the Treatment of Metastatic Castration-resistant Prostate CancerClinical Cancer ResearchJuly 1, 2019Steven Kregel et al.MYC (Cell Signaling Cat. #5605S), PSA (Dako Cat. #A0562), and TXNIP (Cell Signaling, D5F3E, Cat. # 4715). All antibodies were employed at dilutions suggested by the manufacturers. Whole-cell lysates collected

(19) Functional and Mechanistic Interrogation of BET Bromodomain Degraders for the Treatment of Metastatic Castration Resistant Prostate CancerClin. Cancer Res.March 27, 2019Steven Kregel, Rohit Malik, Irfan A. Asangani, Kari Wilder-Romans, Thekkelnaycke Rajendiran, Lanbo Xiao, Josh N. Vo, Tanu Soni, Marcin Cieslik, Ester Fernadez-Salas, et al.MYC (Cell Signaling Cat. #5605S), PSA (Dako Cat. #A0562), and TXNIP (Cell Signaling, D5F3E, Cat. # 4715). All antibodies were employed at dilutions suggested by the manufacturers. Whole-cell lysates collected

(20) MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cellsNature communicationsDecember 3, 2018Bahat A, Goldman A, Zaltsman Y, Khan DH, Halperin C, Amzallag E, Krupalnik V, Mullokandov M, Silberman A, Erez A, et al.

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TRAF1 (45D3) Rabbit mAb

TRAF1 (45D3) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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TRAF1 (45D3) Rabbit mAb from Cell Signaling Technology

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