ASK1 Antibody 3762S from Cell Signaling Technology

Product Specs
ItemASK1 Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number3762S
Quantity100 µl
ApplicationsW
ReactivityH
TargetASK1
HostRabbit
NCBI Gene AliasesASK1, MAPKKK5, MEKK5
NCBI Full Gene Namemitogen-activated protein kinase kinase kinase 5
ClonalityPolyclonal
Research AreaMAP Kinase Signaling
Molecular Weight155

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Multi-omics analysis elucidates the therapeutic mechanisms of the Quzhi formula in metabolic dysfunction-associated steatohepatitis targeting gut microbiota, lipid metabolism, and the role of its metabolite fraxinFrontiers in PharmacologyNovember 3, 2025Jiao-Xiang Wu, Yue-Lan Wu, Mei-Fang Li, Nian Liu, Ying Liu, Yan-Ping Huang, Yuan Gan, Xiao-Yu Wang, Hai-Sheng Chai, Jin Xu, et al.Protein,Manufacturer,Product number,Source ASK1,CST,3762S,Rabbit Phospho-JNK,proteintech,80024-1-RR,Rabbit/IgG JNK,proteintech,66210-1-Ig,Mouse/IgG1 P62/SQSTM1,proteintech,18420-1-AP,Rabbit/IgG BAX,proteintech,50599-2-Ig,Rabbit/IgG Bcl2,proteintech,26593-1-AP,Rabbit/IgG LC3B,proteintech,18725-1-AP,Rabbit/IgG ATG7,proteintech,10088-2-AP,Rabbit/IgG NRF2,CST,12721S,Rabbit/IgG AMPKα,CST,2532S,Rabbit/IgG AMPKβ1/2,CST,4150S,Rabbit/IgG Phospho-AMPKα,CST,2535S,Rabbit/IgG Antibody

(2) Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosisNature Cardiovascular ResearchJanuary 10, 2025Meiming Su, Wenqi Zhao, Hui Jiang, Yaping Zhao, Zhaopeng Liao, Zhenghong Liu, Mengyun Xu, Shanshan Jiang, Lili Wu, Yi Yang, et al.17; 1:1,000), anti-JNK (Proteintech, no. 66210–1-Ig, lot no. 10023911; 1:1,000), anti-ASK1 (CST, no. 3762; 1:1000), anti-CD144 (BD Biosciences, no. 555289 and no. 555661, lot no. 1076252; 1:100), anti-CD31

(3) Follicle stimulating hormone controls granulosa cell glutamine synthesis to regulate ovulationProtein & CellJuly 1, 2024Kai-Hui Zhang, Fei-Fei Zhang, Zhi-Ling Zhang, Ke-Fei Fang, Wen-Xing Sun, Na Kong, Min Wu, Hai-Ou Liu, Yan Liu, Zhi Li, et al.this research were purchased from the following sources: ASK1 (Cell Signaling Technology, Cat. No. 3762), p-ASK1 (Cell Signaling Technology, Cat. No. 3765), JNK (Cell Signaling Technology, Cat. No. 9252),

(4) miR-147b mediated suppression of DUSP8 promotes lung cancer progressionOncogeneApril 1, 2024Turkowski K, Herzberg F, Günther S, Weigert A, Haselbauer T, Fink L, Brunn D, Grimminger F, Seeger W, Sültmann H, et al.from Abcam (Cambridge, UK), SAPK/JNK (1:1000 #9252), phospho-SAPK/JNK (1:1000, #4668), ASK1 (1:1000, #3762), phospho-ASK1 (1:1000, #3764), SEK1/MKK4 (1:1000, #9152), phospho-SEK1/MKK4 (1:1000, #9156), MKK7 (1:1000,

(5) ASK1-K716R reduces neuroinflammation and white matter injury via preserving blood-brain barrier integrity after traumatic brain injuryJournal of neuroinflammationOctober 24, 2023Meng S, Cao H, Huang Y, Shi Z, Li J, Wang Y, Zhang Y, Chen S, Shi H, Gao Y.ASK1 enrichment was achieved using SureBeads G Beads (#1614021, Bio-Rad) and rabbit anti-ASK1 (1:1000, 3762, Cell signaling Technology). ASK1 kinase activity was assessed using the HTRF KinEASE-STK S3 kit (62STPEB,

(6) Short Arrestin-3-Derived Peptides Activate JNK3 in CellsInternational Journal of Molecular SciencesAugust 4, 2022Nicole A. Perry-Hauser, Tamer S. Kaoud, Henriette Stoy, Xuanzhi Zhan, Qiuyan Chen, Kevin N. Dalby, Tina M. Iverson, Vsevolod V. Gurevich, Eugenia V. Gurevichwith respective primary antibodies (Cell Signaling Technology, Inc., Danvers, MA, USA) anti-ASK1 (#3762S), anti-phospho-JNK (#9251), anti-SAPK/JNK (#4668P), anti-GST (#2625), or anti-HA (#3724), followed by

(7) Fluoxetine attenuates apoptosis in early brain injury after subarachnoid hemorrhage through Notch1/ASK1/p38 MAPK signaling pathwayBioengineeredApril 1, 2022Liu M, Zhong W, Li C, Su W.BCl-2 (ab182858), Cytochrome C (ab133504), Bax (ab32503), P-ASK1 (#3765, Cell Signaling), T-ASK1 (#3762, Cell Signaling), P-p38 (sc-166,181),T-p38 (sc-7972), and β-actin (sc-47,778) primary antibodies. Later,

(8) Lidocaine Alleviates Sepsis-Induced Acute Lung Injury in Mice by Suppressing Tissue Factor and Matrix Metalloproteinase-2/9Oxidative Medicine and Cellular LongevityNovember 12, 2021Binbin Zheng, Hongbo Yang, Jianan Zhang, Xueli Wang, Hao Sun, Fan Hu, Qian Li, Liping Jiang, Yue Su, Qilin Peng, et al.AMP-activated protein kinase (p-AMPK) (Thr172; catalog no. 2531), phosphorylated ASK1 (catalog no. 3762S), and phosphorylated p38 mitogen-activated protein kinase (p38; Tyr180/Tyr182; catalog no. 9211) was

(9) Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysisBMJMarch 25, 2021Jennifer A Watt, Zahra Goodarzi, Areti Angeliki Veroniki, Vera Nincic, Paul A Khan, Marco Ghassemi, Yonda Lai, Victoria Treister, Yuan Thompson, Raphael Schneider, et al.with dementia: a cluster randomized trial. Int J Geriatr Psychiatry 2012;27:1163-71. doi:10.1002/gps.3762 118 Erdal A, Flo E, Aarsland D, Ballard C, Slettebo DD, Husebo BS. Efficacy and Safety of Analgesic

(10) The SGLT2 inhibitor Empagliflozin attenuates interleukin-17A-induced human aortic smooth muscle cell proliferation and migration by targeting TRAF3IP2/ROS/NLRP3/Caspase-1-dependent IL-1β and IL-18 secretionCellular signallingJanuary 1, 2021Sukhanov S, Higashi Y, Yoshida T, Mummidi S, Aroor AR, Jeffrey Russell J, Bender SB, DeMarco VG, Chandrasekar B.dilutions/concentrations were used: TRAF3IP2 (1:400; NB100–56740, Novus Biologicals, Centennial, CO), ASK1 (1:1000; #3762, Cell Signaling Technology/CST, Danvers, MA), Tubulin (1:1000; #2144, CST), p-p65 (1:1000; #3031, CST),

(11) FBXW7 regulates epithelial barrier impairment in human bronchial epithelial cells in vitro by targeting apoptosis signal-regulating kinase1 via the p38 pathwayBIOCELLJanuary 1, 2021JINGRONG SONG, JUAN KANG, WEI LV, YAN DONG, XIAOYING ZHANG(ab190085), anti-E-cadherin (ab40772), anti-p-p38 (ab195049), anti-p38 (ab31828) from Abcam, and antiASK1 (#3762), anti-GAPDH (#5174), and HRP-conjugated secondary antibodies from Cell Signaling Technology (MA, USA),

(12) Monomeric CRP Aggravates Myocardial Injury After Myocardial Infarction by Polarizing the Macrophage to Pro-Inflammatory Phenotype Through JNK Signaling PathwayJournal of inflammation researchJanuary 1, 2021Zha Z, Cheng Y, Cao L, Qian Y, Liu X, Guo Y, Wang J.anti-p-JNK (Thr183/Tyr185,4668S, CST, America), anti-JNK (66210-1-Ig, Proteintech, America), anti-ASK1 (3762S, CST, America), and anti-Smad2/3 (8685S, CST, America) antibodies. Mouse monoclonal anti-GAPDH antibody

(13) Empagliflozin reduces high glucose-induced oxidative stress and miR-21-dependent TRAF3IP2 induction and RECK suppression, and inhibits human renal proximal tubular epithelial cell migration and epithelial-to-mesenchymal transitionCellular signallingApril 1, 2020Das NA, Carpenter AJ, Belenchia A, Aroor AR, Noda M, Siebenlist U, Chandrasekar B, DeMarco VG.caspase-3 (1:5000; ab32499, abcam), p65 (1:1000; #3033; CST), p-p65 (1:1000; #3031; CST), ASK1 (1:1000; #3762, CST), p-p38 MAPK (1:1000; #4631, CST), p38 MAPK (1:1000; #8690, CST), RAGE (1:1000; #6996; CST), MMP2

(14) IRE1α kinase-mediated unconventional protein secretion rescues misfolded CFTR and pendrinScience advancesFebruary 1, 2020Park H, Shin DH, Sim JR, Aum S, Lee MG.anti–phospho-S724 IRE1α (Abcam, ab48187), anti-XBP1 (Abcam, ab198999), anti-ASK1 (Cell Signaling Technology, 3762), anti–phospho-Thr845 ASK1 (Cell Signaling Technology, 3765), anti-BiP (Cell Signaling Technology, 3177),

(15) WIDEBAND DESIGNS OF SECTORAL MICROSTRIP ANTENNAS USING PARASITIC ARC SHAPE PATCHESProgress In Electromagnetics Research CJanuary 1, 2020Amit A. Deshmukh, Sanjay B. DeshmukhAntenna For On-Body Communication,” IEEE Transactions on Antennas and Propagation, Vol. 65, No. 7, 3762–3765, 2017. 21. CST Microwave Studio suite, Version 2019. 22. Deshmukh, A. A. and S. B. Deshmukh, “Wide

(16) Hsp70 Interacts with Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 To Regulate p38MAPK Stability and Myoblast Differentiation during Skeletal Muscle RegenerationMolecular and cellular biologyDecember 15, 2018Fan W, Gao XK, Rao XS, Shi YP, Liu XC, Wang FY, Liu YF, Cong XX, He MY, Xu SB, et al.Cell Signaling Technology included the following: anti-pp38MAPK (4511), anti-MKK3 (8535), anti-MKK6 (8550), anti-ASK (3762), anti-AKT, antiPI3K, anti-MK2 (7421), anti-MK3 (3043), and anti-JNK (9252). Antibodies from Developmental

(17) Corosolic acid induces cell cycle arrest and cell apoptosis in human retinoblastoma Y-79 cells via disruption of MELK-FoxM1 signalingOncology reportsJune 1, 2018Wang K, Zhu X, Yao Y, Yang M, Zhou F, Zhu L.Cell Signaling Technology, Inc.), caspase-9 (cat. no. ab32539; Abcam), caspase-3 (cat. no. 9662), ASK1 (cat. no. 3762), p-JNK (cat. no. 9255), JNK (cat. no. 9252), p-p38 (cat. no. 9216), p38 (cat. no. 9212), FoxM1 (cat.

(18) S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancerTheranosticsJanuary 1, 2018Huang Y, Hu K, Zhang S, Dong X, Yin Z, Meng R, Zhao Y, Dai X, Zhang T, Yang K, et al.

(19) PDGF/VEGF-Related Receptor Affects Transglutaminase Activity to Control Cell Migration During Crustacean HematopoiesisStem Cells and DevelopmentOctober 15, 2017Kingkamon Junkunlo, Kenneth Söderhäll, Chadanat Noonin, Irene Söderhällreceptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1. Mol Cell Biol 33: 3762–3779. 25. Lemmon MA and J Schlessinger (2010). Cell signaling by receptor tyrosine kinases. Cell 141:

(20) Solanine-induced reactive oxygen species inhibit the growth of human hepatocellular carcinoma HepG2 cellsOncology LettersMarch 1, 2016XUE-QIN MENG, WEI ZHANG, FENG ZHANG, SHENG-YONG YIN, HAI-YANG XIE, LIN ZHOU, SHU-SEN ZHENGAnti‑apoptosis signal‑regulating kinase 1 (ASK1; polyclonal rabbit anti‑human; dilution, 1:1,000; catalog no., 3762; Cell Signaling Technology Inc., Danvers, MA, USA), anti‑thioredoxin binding protein 2 (TBP‑2; monoclonal mouse

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ASK1 Antibody

ASK1 Antibody from Cell Signaling Technology

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Cell Signaling Technology

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ASK1 Antibody from Cell Signaling Technology

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