PRK2 Antibody 2612S from Cell Signaling Technology

Product Specs
ItemPRK2 Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number2612S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R
TargetPRK2
HostRabbit
NCBI Gene AliasesPAK2, PRK2, PRKCL2, PRO2042, Pak-2, STK7
NCBI Full Gene Nameprotein kinase N2
ClonalityPolyclonal
Research AreaCa, cAMP and Lipid Signaling
Molecular Weight140

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) TRAF1 S146 is constitutively phosphorylated in OP9-cultured primary chronic lymphocytic leukemia cells by PKN1/2ImmunohorizonsAugust 17, 2026Birinder Ghumman, Laura Nicolucci, Mark D Minden, Tania H Watts, Ali A Abdul-SaterAnti-TRAF1 (Cell Signaling Technology [CST] clone 45D3, catalog [cat] #4715), anti-PKN2 (CST, cat #2612), and anti-GAPDH (CST, cat #2118) were purchased from New England Biolabs (Whitby, Canada). Anti-PKN1

(2) PKN2 deficiency leads both to prenatal ‘congenital’ cardiomyopathy and defective angiotensin II stress responsesBiochemical JournalJuly 15, 2022Jacqueline J.T. Marshall et al.all samples were normalised to the mean of the controls. Primary antibodies for total PKN2 (Cat. No. 2612), phospho-PKN1/2 (Cat. No. 2611) and GAPDH (Cat. No. 2118) were from Cell Signalling Technology. Antibodies

(3) PKN2 deficiency leads both to prenatal ‘congenital’ cardiomyopathy and defective angiotensin II stress responsesBiochem JJune 22, 2022Jacqueline J.T. Marshall, Joshua J. Cull, Hajed O. Alharbi, May Zaw Thin, Susanna T.E. Cooper, Christopher Barrington, Hannah Vanyai, Thomas Snoeks, Bernard Siow, Alejandro Suáarez-Bonnet, et al.all samples were normalised to the mean of the controls. Primary antibodies for total PKN2 (Cat. No. 2612), phospho-PKN1/2 (Cat. No. 2611) and GAPDH (Cat. No. 2118) were from Cell Signalling Technology. Antibodies

(4) Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of Its Interaction With ActinCirculationNovember 19, 2019Sakaguchi T, Takefuji M, Wettschureck N, Hamaguchi T, Amano M, Kato K, Tsuda T, Eguchi S, Ishihama S, Mori Y, et al.online-only Data Supplement). The antibodies to phospho-PKN1 (Thr774)/ PKN2 (Thr816, No. 2611) and PKN2 (No. 2612) were from Cell Signaling Technology (Beverly, MA); the antibodies to c-Myc (017-21871) and green fluorescent

(5) Mitochondrial translation requires folate-dependent tRNA methylationNatureFebruary 1, 2018Raphael J. Morscher, Gregory S. Ducker, Sophia Hsin-Jung Li, Johannes A. Mayer, Zemer Gitai, Wolfgang Sperl, Joshua D. Rabinowitz

(6) GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growthScientific reportsJanuary 22, 2018Uemura T, Kametaka S, Waguri S.

(7) Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodentsPloS oneJanuary 1, 2018Southard SM, Kotipatruni RP, Rust WL.

(8) Protein kinase N2 regulates AMP kinase signaling and insulin responsiveness of glucose metabolism in skeletal muscleAmerican Journal of Physiology-Endocrinology and MetabolismOctober 1, 2017Maxwell A. Ruby, Isabelle Riedl, Julie Massart, Marcus Åhlin, Juleen R. Zierathmuscle) 8697 27–583 15200 A5541 2611 9271 4056 9272 9331 9315 8619 07–741 5536 2983 2531 2532 3661 3676 sc-16 25778 2211 2317 2612 Cell Signaling Technology Prosci Abcam Sigma Cell Signaling Technology Cell Signaling Technology Cell

(9) BRCT-domain protein BRIT1 influences class switch recombinationProceedings of the National Academy of Sciences of the United States of AmericaAugust 1, 2017Yen WF, Chaudhry A, Vaidyanathan B, Yewdell WT, Pucella JN, Sharma R, Liang Y, Li K, Rudensky AY, Chaudhuri J.(07-164; Millipore), 53BP1 (Novus Biologicals), and BRIT1 (no. 4120; Cell Signaling Technology and no. 2612; Abcam). Splenic B cells from 8- to 10-wk-old mice were isolated by CD43− selection (Miltenyi Biotec)

(10) Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDSNature immunologyAugust 1, 2016Park YH, Wood G, Kastner DL, Chae JJ.anti-actin antibody (sc-1615); anti-myc antibody (sc-40, Santa Cruz Biotechnology); anti-PKN2 antibody (2612, Cell Signaling); or anti-V5 antibody (Invitrogen). Secreted IL-1β was also measured in supernatant

(11) A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fateNature chemical biologyJune 1, 2016Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, et al.

(12) Signaling Cascades Governing Cdc42-Mediated Chondrogenic Differentiation and Mensenchymal CondensationGeneticsMarch 1, 2016Wang JR, Wang CJ, Xu CY, Wu XK, Hong D, Shi W, Gong Y, Chen HX, Long F, Wu XM.p-p38 (4511), p-Smad5 (13820), AKT (9272), Erk (4695), JNK (9252), p38 (9212), Smad5 (9517), Pak1 (2612) and N-cadherin (4061) were from Cell Signaling Technology (Danvers, MA). Antibodies against AP (ab95462),

(13) Identification of therapeutic targets for cancer: Proteomic technologies and strategies are the key to successBiomedical Research JournalJanuary 1, 2015RukminiB Govekar2014;9(11):e110736. Parker S, Raedschelders K, Van Eyk J. Emerging leukemia. Cell Signalling 2013;25(12):2604– proteomic 2612. context-dependent cellular signaling events: A Lihong H, Linlin G, Yiping G, Yang S, Xiaoyu Q, Zhuzhu

(14) Mandatory communication skills training for oncologists: enforcement does not substantially impact satisfactionSupportive Care in CancerOctober 1, 2014CÃ©line Bourquin, Friedrich Stiefel, JÃ¼rg Bernhard, Gabriella Bianchi Micheli, Liselotte Dietrich, Christoph HÃ¼rny, Brigitta WÃ¶ssmer, Alexander Kissfor physicians specializing in medical oncology since 2006 [16]. Physicians’ satisfaction with 2612 training on a voluntary basis compared with mandatory training is of relevance since participants who

(15) Gene Expression Profiling from a Prostate Cancer PC-3 Cell Line Treated with Salinomycin Predicts Cell Cycle Arrest and Endoplasmic Reticulum StressJournal of Cancer Science & TherapyJanuary 1, 2013Kwang Youn Kim(1995) Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol Cell Biol 15: 2612-2624. 11. Agarwal R (2000) Cell signaling and regulators of cell cycle as molecular targets for prostate cancer

(16) Grey and White Matter Changes across the Amyotrophic Lateral Sclerosis-Frontotemporal Dementia ContinuumPLoS ONEAugust 29, 2012Patricia Lillo, Eneida Mioshi, James R. Burrell, Matthew C. Kiernan, John R. Hodges, Michael HornbergerWeiner MW, et al. (2005) Neuroanatomical correlates of behavioural disorders in dementia. Brain 128: 2612–2625. 51. Lillo P, Mioshi E, Zoing MC, Kiernan MC, Hodges JR (2011) How common are behavioural changes

(17) Site recognition and substrate screens for PKN family proteinsBiochemical JournalSeptember 15, 2011Alejandra Collazos, Nicholas Michael, Richard D. H. Whelan, Gavin Kelly, Harry Mellor, Leon C. H. Pang, Nick Totty, Peter J. ParkerAbcam (antibody 78283). PKN1 antibody (BD 610687) was purchased from BD biosciences, PKN2 antibody (Cat 2612) was from Cell Signalling and PKN3 antibody (NBP1-30102) from Novus biologicals. Tubulin α clone B-5-1-2

(18) Interaction with receptor for activated C-kinase 1 (RACK1) sensitizes the phosphodiesterase PDE4D5 towards hydrolysis of cAMP and activation by protein kinase CBiochemical JournalNovember 15, 2010RebeccaÂ J. Bird, GeorgeÂ S. Baillie, StephenÂ J. YarwoodPDE4D5 interaction with the signalling scaffold proteins, β-arrestin and RACK1. Cell. Signalling 19, 2612–2624 27 Lynch, M. J., Baillie, G. S., Mohamed, A., Li, X., Maisonneuve, C., Klussmann, E., van Heeke,

(19) Site recognition and substrate screens for PKN family proteinsThe Biochemical journalJanuary 1, 0001"Collazos A, Michael N, Whelan RD, Kelly G, Mellor H, Pang LC, Totty N, Parker PJ."Abcam (antibody 78283). PKN1 antibody (BD 610687) was purchased from BD biosciences, PKN2 antibody (Cat 2612) was from Cell Signalling and PKN3 antibody (NBP1-30102) from Novus biologicals. Tubulin α clone B-5-1-2

(20) "PHI-1, an Endogenous Inhibitor Protein for Protein Phosphatase-1 and a Pan-Cancer Marker, Regulates Raf-1 Proteostasis"BiomoleculesJanuary 1, 0001"Kirkbride JA, Nilsson GY, Kim JI, Takeya K, Tanaka Y, Tokumitsu H, Suizu F, Eto M."anti-CDK4 (1:2000, MyBioSource #MBS127817, San Diego, CA, USA), anti-PKN2 (1:2000, Cell Signaling #2612), anti-HSP70 (1:2000, Cell Signaling #4822), anti-P-MEK1/2 (1:2000, Cell Signaling #9121), and anti-GAPDH

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PRK2 Antibody

PRK2 Antibody from Cell Signaling Technology

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Cell Signaling Technology

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PRK2 Antibody from Cell Signaling Technology

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