Tuberin/TSC2 (28A7) Rabbit mAb 3635S from Cell Signaling Technology

Product Specs
ItemTuberin/TSC2 (28A7) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number3635S
Quantity100 µl
ApplicationsW, IP
ReactivityH
TargetTuberin/TSC2
HostRabbit
NCBI Gene AliasesLAM, PPP1R160, TSC4
ClonalityMonoclonal
NCBI Full Gene NameTSC complex subunit 2
Research AreaPI3K / Akt Signaling
IsotypeIgG
Clone28A7
Molecular Weight200

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Identification of Meibomian gland stem cell populations and mechanisms of agingNat CommunFebruary 15, 2025Xuming Zhu, Mingang Xu, Celine Portal, Yvonne Lin, Alyssa Ferdinand, Tien Peng, Edward E. Morrisey, Andrzej A. Dlugosz, Joseph M. Castellano, Vivian Lee, et al.anti-GLI2 (Novus Biologicals #NB600-874SS, 1:200, RRID AB_10001953); Goat anti-GLI2 (R&D Systems #AF-3635, 1:50, RRID AB_2111902); Rabbit anti-Acetylated-Lysine (Cell Signaling Technology #9441 s, 1:100, RRID

(2) LAM Cells as Potential Drivers of Senescence in Lymphangioleiomyomatosis MicroenvironmentInternational Journal of Molecular SciencesJune 24, 2022Clara Bernardelli, Silvia Ancona, Melania Lazzari, Antonella Lettieri, Piera Selvaggio, Valentina Massa, Cristina Gervasini, Fabiano Di Marco, Raffaella Chiaramonte, Elena Lesma°C with antibodies against Tuberin (1:500; Cell Signalling Technologies, Danvers, MA, USA, Cat. No. 3635), p16INK4A(D7C1M) (1:1000; Cell Signalling Technologies, Cat. No. 80772), phospho-S6 (Ser235/236) (1:1000;

(3) Acute normobaric hypoxia blunts contraction-mediated mTORC1- and JNK-signaling in human skeletal muscleActa physiologica (Oxford, England)February 1, 2022Moberg M, Apró W, Horwath O, van Hall G, Blackwood SJ, Katz A.#12753; total, #8054), LC3b (#2775), GABARAP (#13733), BNIP3 (#44060) TSC2 (Ser1387, #5584; total, #3635) PRAS40 (Thr246, #13175; total, #2691) and p38 (Thr180/Thr182, #4511; total, #8690), were purchased

(4) Differential Modulation of Matrix Metalloproteinases-2 and -7 in LAM/TSC CellsBiomedicinesNovember 24, 2021Ancona S, Orpianesi E, Bernardelli C, Chiaramonte E, Chiaramonte R, Terraneo S, Di Marco F, Lesma E.Cell Signaling Technologies, Cat. No. 71031), tuberin (1:1000; Cell Signaling Technologies, Cat. No. 3635), phospho-S6 (1:1000; Cell Signaling Technologies, Cat. No. 2211), or β-actin (1:1000; Sigma-Aldrich,

(5) ANXA6 suppresses the tumorigenesis of cervical cancer through autophagy inductionClinical and translational medicineOctober 1, 2020Sun X, Shu Y, Xu M, Jiang J, Wang L, Wang J, Huang D, Zhang J.Cell Signaling Technology, 17366), PI3K (Cell Signaling Technology, 3358), TSC2 (Cell Signaling Technology, 3635), phospho‐AKT (Cell Signaling Technology, 4060), AKT (Cell Signaling Technology, 9272), phospho‐RPS6

(6) Nox4 is a Target for Tuberin Deficiency SyndromeScientific reportsFebruary 28, 2018Shi Q, Viswanadhapalli S, Friedrichs WE, Velagapudi C, Szyndralewiez C, Bansal S, Bhat MA, Choudhury GG, Abboud HE.anti-tuberin (sc-893) from Santa Cruz; monoclonal anti-beta-actin (A-5441) from Sigma; anti-human tuberin (#3635 s), anti-S6 kinase (#2708 s), anti-phospho-S6 kinase (T389) (#9205 s), anti-mTOR (#2983) were obtained

(7) mTORC1 Activation by Loss of Tsc1 in Myelinating Glia Causes Downregulation of Quaking and Neurofascin 155 Leading to Paranodal Domain DisorganizationFrontiers in cellular neuroscienceJanuary 1, 2018Shi Q, Saifetiarova J, Taylor AM, Bhat MA.NeuroMab), mouse anti-Kv1.2 (75-008, NeuroMab), mouse anti-β-Actin (A-5441, Sigma), anti-human tuberin (#3635s, Cell Signaling), anti-S6 kinase (#2708s, Cell Signaling), anti-phospho-S6 kinase (T389; #9205s), anti-pan-Qk

(8) Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespanNature communicationsDecember 22, 2017Wang C, Niederstrasser H, Douglas PM, Lin R, Jaramillo J, Li Y, Oswald NW, Zhou A, McMillan EA, Mendiratta S, et al.1:1,000), total p70-S6K (cat. 2708, 1:1,000), TSC2-pThr1462 (cat. 3611, 1:1,000), total TSC2 (cat. 3635, 1:1,000), AKT-pThr308 (cat. 2965, 1:1,000), pan AKT (cat. 4691, 1:1,000), IP3R1 (cat. 3763, 1:1,000),

(9) Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in miceScientific ReportsDecember 1, 2017Hong-Mei Zhang, Vivian Diaz, Michael E. Walsh, Yiqiang Zhang#2775) (all from Cell Signaling, Beverly, MA); hTSC1 (Epitomics, Cat. #1744-1; Cell Signaling, Cat. #3635); PKCα (Cat. ab32376), pPCKα(Ser657) (Cat. ab180848) (from Abcam, Cambridge, MA); GAPDH (from Santa

(10) AKT isoforms have distinct hippocampal expression and roles in synaptic plasticityeLifeNovember 27, 2017Levenga J, Wong H, Milstead RA, Keller BN, LaPlante LE, Hoeffer CA.Cell Signaling 27C10), phospho-TSC2 S939 (1:1000, Cell signaling 3615), TSC2 (1:1000, Cell Signaling 3635), phospho-PDK1 S241 (1:3000, Cell Signaling 3061), PDK1 (1:2000, Cell Signaling 3062), phospho-S6 235/236

(11) Activation of the unfolded protein response in sarcoma cells treated with rapamycin or temsirolimusPLOS ONESeptember 19, 2017Joseph W. Briggs, Ling Ren, Kristi R. Chakrabarti, Yien Che Tsai, Allan M. Weissman, Ryan J. Hansen, Daniel L. Gustafson, Yousuf A. Khan, Jonathan D. Dinman, Chand Khanna

(12) Marine actinomycete crude extracts with potent TRAIL-resistance overcoming activity against breast cancer cellsOncology ReportsJune 1, 2017Mohammed I.Y. Elmallah, Olivier Micheau, Mennat Allah G. Eid, Ali M.S. Hebishy, Mohamed S. Abdelfattahwere obtained from Cell Signaling Technology (Ozyme, St. Quentin Yvelines, ONCOLOGY REPORTS 37: 3635-3642, 2017 3637 Table I. Cytotoxic effects of 21 marine actinomycete crude extracts with and without

(13) 20S immunoproteasomes remove formaldehyde-damaged cytoplasmic proteins suppressing caspase-independent cell deathScientific reportsApril 5, 2017Ortega-Atienza S, Krawic C, Watts L, McCarthy C, Luczak MW, Zhitkovich A.

(14) Health-related quality of life, visual function and treatment satisfaction following intravitreal dexamethasone implant for diabetic macular edemaPatient Preference and AdherenceApril 1, 2017Jayashree Ramu, Irini Chatziralli, Yit Yang, Geeta Menon, Clare Bailey, Michael Eckstein, Philip Hykin, Sobha Sivaprasadneovascular AMD: validation studies from two phase 3 clinical trials. Invest Ophthalmol Vis Sci. 2009;50(8):3629–3635. 28. Alagöz N, Alagöz C, Yılmaz I, et al. Immediate intraocular pressure changes following intravitreal

(15) Functional kinomics establishes a critical node of volume-sensitive cation-Cl− cotransporter regulation in the mammalian brainScientific ReportsDecember 1, 2016Jinwei Zhang et al.was purchased from Sigma-Aldrich; the anti-PDK1 antibody (3062) and the Tuberin/TSC2 (28A7) antibody (3635) were purchased from Cell Signaling Technology. Secondary antibodies coupled to horseradish peroxidase

(16) A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpressionMolecular systems biologyDecember 11, 2015Shields BB, Pecot CV, Gao H, McMillan E, Potts M, Nagel C, Purinton S, Wang Y, Ivan C, Kim HS, et al.(pAKT (T308) #2965, pAKT (S473) #4060, panAKT #4691, pGSK3β (S9) #9327, GSK3β #9315, p27 #3686, TSC2 #3635, pMEK (S217/221) #9121, MEK1/2 #9122, ERK1/2 #9102, pERK (T202/Y204) #4370, SMAD4 #9515, pSMAD3 (S423/425)

(17) A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferationOncotargetOctober 21, 2013Jennifer Munkley, Prabhakar Rajan, Nicholas P. Laferty, Caroline Dalgliesh, Robert M. Jackson, Craig N. Robson, Hing Y. Leung, David J. Elliottpolyclonal antibody (4308, Cell Signalling Technology), anti-TSC2 N-term rabbit polyclonal antibody (3635, Cell Signalling Technology), anti-p70-S6K (9234 Cell Signalling Technology), anti-Sam68 rabbit polyclonal antibody

(18) Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrainJournal of Comparative NeurologyFebruary 15, 2013Carlita B. Favero, Rasha N. Henshaw, Cynthia M. Grimsley-Myers, Ayushma Shrestha, David R. Beier, Noelle D. Dwyerfrom three brains each of control (gray) and mutant (black), with 4174 total control cells scored and 3635 total mutant cells. For Tbr1+ cells, p = 0.77; for Satb2+ cells, p = 0.98; for cells expressing neither

(19) The Human Papillomavirus Type 16 E6 Oncoprotein Activates mTORC1 Signaling and Increases Protein SynthesisJournal of VirologySeptember 15, 2010Jennifer M. Spangle, Karl MüngermTOR S2448 (2971), S6K (9202), S6K T389 (9206), S6 (2317), S6 S235/36 (4858), S6 240/44 (4838), TSC2 (3635), 4E-BP1 (9644), 4E-BP1 T37/46 (2855), 4E-BP1 S65 (9451), 4E-BP1 T70 (9455), Akt (9272), Akt S473 (4060), Akt

(20) Consecutive bouts of diverse contractile activity alter acute responses in human skeletal muscleJournal of Applied PhysiologyApril 1, 2009Vernon G. Coffey, Henriette Pilegaard, Andrew P. Garnham, Brendan J. O'Brien, John A. Hawley-p70 S6KThr389 (no. 9206), -S6 ribosomal proteinSer235/6 (no. 4856), anti-Akt (no. 9272), -TSC2 (no. 3635), ⫺p70 S6K (no. 9202), -S6 ribosomal protein (no. 2217), and -adenosine monophosphate kinase-␣ (AMPK␣)

Be the First to Write a Review!

Tuberin/TSC2 (28A7) Rabbit mAb

Tuberin/TSC2 (28A7) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (20)

Reviews

Tuberin/TSC2 (28A7) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map