Dicer (D38E7) Rabbit mAb 5362S from Cell Signaling Technology

Product Specs
ItemDicer (D38E7) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number5362S
Quantity100 µl
ApplicationsW, IP
ReactivityH
TargetDicer1
HostRabbit
NCBI Gene AliasesDCR1, Dicer, Dicer1e, GLOW, HERNA, K12H4.8-LIKE, MNG1, RMSE2, aviD
ClonalityMonoclonal
NCBI Full Gene Namedicer 1, ribonuclease III
Research AreaTranslational Control
IsotypeIgG
CloneD38E7
Molecular Weight220

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) The REDD1–NF-κB–miRNAs–eNOS/SIRT1 axis mediates obesity-induced endothelial cell senescence and hypertensionNature CommunicationsMarch 12, 2026Yoon Kyung Choi, Dong-Keon Lee, Minsik Park, Junyoung Byeon, Woo-Young Nam, Thuy Linh Lai, Kyu Nam Kim, Okhwa Kim, Sungwoo Ryoo, Jeong-Hyung Lee, et al.primary antibodies: ant-eNOS (1:1000, #PA1-037, RRID: AB_325774; Invitrogen), anti-DICER (1:1000, #5362, RRID: AB_2093073; Cell Signaling Technology), anti-IKKβ (1:1000, #2684, RRID: AB_2122298; Cell Signaling Technology

(2) SFTSV NSs interacts with AGO2 to regulate the RNAi pathway for viral replicationJournal of VirologyApril 15, 2025Nasir Javaid, Tae-Won Jang, Yuting Fu, Younho Choibovine serum albumin (BSA) in TBST. The primary antibodies included DICER (clone D38E7, Cell Signaling [5362]), AGO2 (clone C34C6, Cell Signaling [2897]), GFP (clone B-2, Santa Cruz [sc-9996]; clone D5.1, Cell Signaling

(3) PD-L1 expression is mediated by microRNA processing, Wnt/β-catenin signaling, and chemotherapy in Wilms tumorbioRxivDecember 6, 2024Kavita Desai, Patricia D.B. Tiburcio, Austin Warne, Arash Nabbi, Serena Zhou, Sean D. Reiff, Matthew E. Campbell, Kenneth S. Chenfor 24 hours. Primary antibodies used are as follows: DICER1 (1:3000, Cell Signaling Technology, cat. 5362, RRID:AB_10692484), DROSHA (1:3000, Cell Signaling Technology, cat. 3364, RRID:AB_2070685); PD-L1 (1:3000,

(4) IL-1β Induces Human Endothelial Surface Expression of IL-15 by Relieving let-7c-3p Suppression of Protein TranslationJournal of immunology (Baltimore, Md. : 1950)November 1, 2024Mullan CW, Summer L, Lopez-Giraldez F, Tobiasova Z, Manes TD, Yasothan S, Song G, Jane-Wit D, Saltzman WM, Pober JS.antibody at 4°C. Primary antibodies were diluted in blocking buffer and were: DICER (Cell Signaling #5362S, 1:1000), RELA (Santa Cruz-109, 1:1000), β-actin (Cell Signaling #4970, 1:1000). Membranes were washed

(5) DROSHA Regulates Mesenchymal Gene Expression in Wilms TumorMolecular Cancer ResearchAugust 2, 2024Patricia D.B. Tiburcio, Kavita Desai, Jiwoong Kim, Qinbo Zhou, Lei Guo, Xue Xiao, Li Zhou, Aysen Yuksel, Daniel R. Catchpoole, James F. Amatruda, et al.Cell Signaling Technology, cat. 3741, RRID:AB_2070685); DICER1 (1:3000, Cell Signaling Technology, cat. 5362, RRID:AB_10692484); DROSHA (1:3000, Cell Signaling Technology, cat. 3364, RRID:AB_2238644); GAPDH (1:3000,

(6) EZH2-H3K27me3-mediated silencing of mir-139-5p inhibits cellular senescence in hepatocellular carcinoma by activating TOP2AJournal of Experimental & Clinical Cancer ResearchNovember 27, 2023Ke Wang, Xunliang Jiang, Yu Jiang, Jun Liu, Yongtao Du, Zecheng Zhang, Yunlong Li, Xinhui Zhao, Jipeng Li, Rui ZhangRabbit monoclonal antibodies against EZH2 (5246 S), H3K27me3 (9733 S), TOP2A (12,286 S) and Dicer (5362 S) for WB (1:1000), IHC (1:50), and ChIP (1:100) were purchased from Cell Signaling Technology (Cell

(7) SINE RNA of the imprinted miRNA clusters mediates constitutive type III interferon expression and antiviral protection in hemochorial placentasCell host & microbeJuly 12, 2023Wickramage I, VanWye J, Max K, Lockhart JH, Hortu I, Mong EF, Canfield J, Lamabadu Warnakulasuriya Patabendige HM, Guzeloglu-Kayisli O, Inoue K, et al.(Cell Signaling Technology Cat# 2144, RRID:AB_2210548, 1:1000), rabbit anti-DICER1 (D38E7) (Cell Signaling Technology Cat# 5362S, RRID:AB_10692484, 1:1000), rabbit anti-DROSHA (D28B1) (Cell Signaling Technology Cat #3364, RRID:AB_2238644,

(8) The length of uninterrupted CAG repeats in stem regions of repeat disease associated hairpins determines the amount of short CAG oligonucleotides that are toxic to cells through RNA interferenceCell death & diseaseDecember 30, 2022Murmann AE, Patel M, Jeong SY, Bartom ET, Jennifer Morton A, Peter ME.anti-human AGO1 (D84G10, Cell Signaling, #5053) and anti-human DICER Rabbit mAb (D38E7, Cell Signaling #5362). Secondary antibodies for Western blot: Goat anti-rabbit-IgG-HRP (Southern Biotech #SB-4030-05, RRID:AB_2687483).

(9) The Ginsenoside Compound K Suppresses Stem-Cell-like Properties and Colorectal Cancer Metastasis by Targeting Hypoxia-Driven Nur77-Akt Feed-Forward SignalingCancersDecember 20, 2022Zhang M, Shi Z, Zhang S, Li X, To SKY, Peng Y, Liu J, Chen S, Hu H, Wong AST, et al.metastatic CRC. 2. Materials and Methods 2.1. Antibodies and Reagents Anti-Nur77 (#3960), anti-Dicer (#5362), and anti-phospho-Akt (#4060) were purchased from Cell Signaling Technology (Danvers, MA, USA); anti-phospho-serine/threonine

(10) M6A associated TSUC7 inhibition contributed to Erlotinib resistance in lung adenocarcinoma through a notch signaling activation dependent wayJournal of experimental & clinical cancer research : CROctober 16, 2021Li K, Peng ZY, Gao S, Wang QS, Wang R, Li X, Xiao GD, Zhang J, Ren H, Tang SC, et al.Cell Signaling Technology), anti-EGFR (1:2000, #4267, Cell Signaling Technology), anti-DICER1 (1:500, #5362, Cell Signaling Technology), anti-CMYC (1:1500, (9E10): sc-40, Santa Cruz), anti- Snail (1:1000, ab31787,

(11) The Ratio of Toxic-to-Nontoxic miRNAs Predicts Platinum Sensitivity in Ovarian CancerCancer researchAugust 1, 2021Patel M, Wang Y, Bartom ET, Dhir R, Nephew KP, Matei D, Murmann AE, Lengyel E, Peter ME.anti-argonaute-2 antibody (#ab32381, RRID:AB_867543) was purchased from Abcam; anti-Dicer (D38E7) antibody (#5362, RRID:AB_10692484) from Cell Signaling Technology; anti-β-actin antibody (#sc-47778, RRID:AB_2714189)

(12) Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistanceNature communicationsJune 29, 2021Hang Q, Zeng L, Wang L, Nie L, Yao F, Teng H, Deng Y, Yap S, Sun Y, Frank SJ, et al.used: antibodies against DGCR8 (1:2000, Abcam, #ab191875), Dicer (1:1000, Cell Signaling Technology, #5362S), Drosha (1:1000, Cell Signaling Technology, #3364S), Exportin-5 (1:1000, Cell Signaling Technology,

(13) Sequential targeting of YAP1 and p21 enhances the elimination of senescent cells induced by the BET inhibitor JQ1Cell death & diseaseJanuary 25, 2021Zhang HT, Gui T, Liu RX, Tong KL, Wu CJ, Li Z, Huang X, Xu QT, Yang J, Tang W, et al.anti-Sp1 (CST, cat# 9389, USA, 1:1000), anti-p16 (Abcam, cat# ab51243, UK, 1:1000), anti-Dicer (CST, cat# 5362, USA, 1:1000), anti-γ-H2A.X (CST, cat# 9718, 1:1000), anti-p-p65 (CST, cat# 3033, USA, 1:1000), anti-caspase-3

(14) A novel lncRNA PTTG3P/miR-132/212-3p/FoxM1 feedback loop facilitates tumorigenesis and metastasis of pancreatic cancerCell Death DiscoveryDecember 1, 2020Wenyu Liu, Jian Tang, Huiqing Zhang, Fanyang Kong, Huiyun Zhu, Ping Li, Zhaoshen Li, Xiangyu Kong, Kaixuan Wangab137647, UK), PTTG1 (1:2000, Abcam, cat. #ab79546, UK) and Dicer (1:2000, Cell Signaling T, cat. #5362 S); and a secondary antibody (anti-rabbit IgG or anti-mouse IgG; Santa Cruz Biotechnology, USA). Equal

(15) Hippocampal neural stem cells are more susceptible to the neurotoxin BMAA than primary neurons: effects on apoptosis, cellular differentiation, neurite outgrowth, and DNA methylationCell Death & DiseaseOctober 1, 2020Paula Pierozan, Daiane Cattani, Oskar Karlssonin neuronal cells is mediated by oxidative stress: insights to a new toxic model. Mol. Neurobiol. 55, 5362–5376 (2018). 47. Jabaudon, D. Fate and freedom in developing neocortical circuits. Nat. Commun. 8, 16042

(16) The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA BiogenesisCell stem cellOctober 1, 2020Zeng J, Dong S, Luo Z, Xie X, Fu B, Li P, Liu C, Yang X, Chen Y, Wang X, et al.anti-ZIKV envelope antibody (GeneTex, #GTX133314), rabbit polyclonal anti-Dicer antibody (Cell Signaling, #5362), mouse monoclonal anti-Dicer antibody (Novus Biologicals, #NBP2–30699) Appropriate HRP-conjugated secondary

(17) EZH2-mediated Epigenetic Silencing of miR-29/miR-30 targets LOXL4 and contributes to Tumorigenesis, Metastasis, and Immune Microenvironment Remodeling in Breast CancerTheranosticsJuly 9, 2020Huilong Yin et al.Cell Signaling Technology), rabbit anti-H3K27me3 (1:1000, 9733, Cell Signaling Technology), rabbit anti-Dicer1 (1:1000, 5362, Cell Signaling Technology), rabbit anti-LOXL4 (1:1000, 88186, Abcam), mouse anti-β-actin (1:5000, Sigma).

(18) GABPA-dependent down-regulation of DICER1 in follicular thyroid tumoursEndocrine-Related CancerMay 1, 2020Johan O Paulsson, Na Wang, Jiwei Gao, Adam Stenman, Jan Zedenius, Ninni Mu, Weng-Onn Lui, Catharina Larsson, C Christofer Juhlinpolyclonal antibody ABE1047, Millipore, at 1:1000 dilution) and anti-DICER (rabbit MAB D38E7, Cat# 5362, Cell Signaling Technology, at 1:1000 dilution in 5% non-fat milk). Anti-β-actin (mouse MAB from Sigma,

(19) miR-615-3p promotes the epithelial-mesenchymal transition and metastasis of breast cancer by targeting PICK1/TGFBRI axisJournal of experimental & clinical cancer research : CRApril 26, 2020Lei B, Wang D, Zhang M, Deng Y, Jiang H, Li Y.anti-p-smad3(#9520 rabbit ser423/425) antibody, anti-smad3(#9523 rabbit) antibody, and anti-Dicer (#5362 rabbit) antibody were purchased from Cell Signaling Technologies (CST). Anti-TGFβ RI (#sc-101,574, mouse)

(20) AGO2 Mediates MYC mRNA Stability in Hepatocellular CarcinomaMolecular cancer research : MCRApril 1, 2020Zhang K, Pomyen Y, Barry AE, Martin SP, Khatib S, Knight L, Forgues M, Dominguez DA, Parhar R, Shah AP, et al.performed using anti-AGO2 (Abcam, cat#. ab186733), anti-MYC (Abcam, cat#. 32072), anti-DICER1 (CST, cat#. 5362S), anti-GAPDH (CST, cat#.5174), and anti-β-ACTIN (Sigma-Aldrich, cat#. A5316). Animal Study Four-week-old

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Dicer (D38E7) Rabbit mAb

Dicer (D38E7) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Dicer (D38E7) Rabbit mAb from Cell Signaling Technology

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