FoxM1 (D12D5) XP ® Rabbit mAb 5436S from Cell Signaling Technology

Product Specs
ItemFoxM1 (D12D5) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $371.00 Inquire
Catalog Number5436S
Quantity100 µl
ApplicationsW, IF-IC
ReactivityH
TargetFOXM1
HostRabbit
NCBI Gene AliasesFKHL16, FOXM1A, FOXM1B, FOXM1C, HFH-11, HFH11, HNF-3, INS-1, MPHOSPH2, MPP-2, MPP2, PIG29, TRIDENT
ClonalityMonoclonal
NCBI Full Gene Nameforkhead box M1
Research AreaCell Cycle / Checkpoint Control
IsotypeIgG
CloneD12D5
Molecular Weight110

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) The Preclinical Effects and Mechanisms of Biofield Therapy on Pancreatic Cancer Cell Growth and MetastasisCancer MedApril 13, 2026Peiying Yang, Daoyan Wei, Sharmistha Chakraborty, Phuong Nguyen, Andrew Cusimano, Defeng Deng, Shafaqmuhammad Iqbal, Monica Nelson, Meng Cui, Jianliang Dai, et al.oxonol) (B438) from Thermo Fisher; and gemcitabine from MD Anderson Pharmacy. Antibodies against FOXM1 (5436), p21 (2947), N‐cadherin (13116), and E‐cadherin (14472) were purchased from Cell Signaling Technology

(2) FOXM1-specific TCR-engineered T cells target non-small cell lung cancerCancer Immunology ResearchMarch 19, 2026Emily Bontekoe, Minying Zhang, Peixin Jiang, Amanda Montoya, Yulia Shulga, Jared K. Slone, Emily Paul, Christopher Polera, Sarah Forward, Barbara Nassif Nassif Rausseo, et al.tumor cell line, H1975, using a monoclonal FOXM1 (D12D5) primary antibody (Cell Signaling Technology, 5436S) and Amersham ECL Rabbit IgG secondary antibody (Cytiva, NA934). Protein lysates were separated on Criterion TGX Stain-Free Precast Gels

(3) FOXM1 regulates platelet-induced anoikis resistance in pancreatic cancer cellsCell Communication and SignalingJanuary 14, 2026Alissa Ernesti-Soldatkin, Carolin T. Neu, Beate Heydel, Ferdinand Krannich, Helmut Laumen, Tony Gutschner, Monika Haemmerlewas quantified using ImageJ [22]. The following primary antibodies were used: FOXM1 (clone D12D5; #5436), cleaved PARP (clone D64E10; #5625), phospho-AKT (Ser473, clone D9E; #4060), AKT (clone C67E7; #4691),

(4) Targeting TAZ-TEAD in minimal residual disease enhances the duration of targeted therapy in melanoma modelsNature CommunicationsNovember 5, 2025Connor A. Ott, Timothy J. Purwin, Pan-Yu Chen, Somenath Chowdhury, George L. Mellor, Kristine Luo, Glenn L. Mersky, Manoela Tiago, William D. Madden, Scott D. Varney, et al.P-ERK1/2 (Thr202/Tyr204) (#9101, 1:1000), Total ERK1/2 (#9102, 1:1000) pan-TEAD (#13295S, 1:1000), FOXM1 (#5436, 1:1000), PAI-1 (#49536, 1:1000), and P-c-Met (Tyr1234/1235) (#3077, 1:1000), and c-Met (#8198, 1:1000),

(5) Elevated NR2F1 underlies the persistence of invasive disease after treatment of BRAF-mutant melanomaJournal of Clinical InvestigationSeptember 16, 2025Manoela Tiago, Timothy J. Purwin, Casey D. Stefanski, Renaira Oliveira da Silva, Mitchell E. Fane, Yash Chhabra, Jelan I. Haj, Jessica L.F. Teh, Rama Kadamb, Weijia Cai, et al.9309), p-S6 (S235/236, no. 4857), p-S6 (S240/244, no. 2215), S6 ribosomal protein (no. 2217), FOXM1 (no. 5436), aurora A/AIK (no. 3092), PLK1 (no. 4513), Wee1 (no. 4936), and RSK1 (no. 9333) (all from Cell Signaling Technology

(6) Epigenetic silencing of DNA sensing pathway by FOXM1 blocks stress ligand-dependent antitumor immunity and immune memoryNat CommunApril 28, 2025Santosh Timilsina, Jian Yu Huang, Nourhan Abdelfattah, Daisy Medina, Deepika Singh, Shahad Abdulsahib, Panneerdoss Subbarayalu, Trong Phat Do, Prabhakar Pitta Venkata, Saif Nirzhor, et al.primary antibody. Slides were incubated with either FOXM1(1:150, Cell Signaling Technologies, Cat #5436) and CD56(1:100, Bio-Rad, Cat #MCA2693GA) or CD3(1:100, Bio-Rad), CD8 (1:150, Biolegend), and ULBP1

(7) MTHFD2 marks pemetrexed resistance in pulmonary adenocarcinoma with EGFR wild typeDiscov OncolApril 20, 2025Sha Yao, Omar Elakad, Xiang Hui Yang, Adnan Raza Altaf, Wen Tao Yu, Hanibal Bohnenberger, Luo Gen PengMAPK (Thr180/Tyr182; catalog #4511), LC3B (catalog #3868), Cyclin B1 (catalog #12231), FoxM1 (catalog #5436), and PD-L1 (catalog #13684), which were procured from Cell Signaling Technology; PARK7 (catalog #ab18257)

(8) Proteogenomic analysis reveals adaptive strategies for alleviating the consequences of aneuploidy in cancerThe EMBO JournalFebruary 10, 2025Jan-Eric Bökenkamp, Kristina Keuper, Stefan Redel, Karen Barthel, Leah Johnson, Amelie Becker, Angela Wieland, Markus Räschle, Zuzana Storchová,Cell Signaling,2947 Mouse anti-p53WB; 1:1000,Santa Cruz,sc-124 Rabbit anti-FOXM1WB; 1:1000IF; 1:100,Cell Signaling,5436 Rabbit anti-Aurora BWB; 1:1000,Abcam,ab2254 Mouse anti-Cdk1WB; 1:1000,Santa Cruz,sc-54 Mouse IgG

(9) Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycleNature communicationsFebruary 9, 2025Kumarasamy V, Wang J, Roti M, Wan Y, Dommer AP, Rosenheck H, Putta S, Trub A, Bisi J, Strum J, et al.4129S), pCDK1 (Y15) (9111 L), CDK1 (Cat # 77055), P16INK4A (D7C1M) (Cat# 80772) and FOXM1 (D12D5) (Cat # 5436S) were purchased from Cell Signaling Technology. The antibodies were diluted by 1000-fold in the antibody

(10) Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancerTherapeutic Advances in Medical OncologyDecember 11, 2024Susmita Ghosh, Fan Fan, Reid Powell, Yong Sung Park, Clifford Stephan, E. Scott Kopetz, Lee M. Ellis, Rajat BhattacharyaRRID:AB_10693314), retinoblastoma protein (pRB; Cat# 8516; RRID:AB_11178658), forkhead box protein M1 (FOXM1; Cat# 5436; RRID:AB_10692483), and phospho-histone H2AX (pH2AX; Cat# 9718; RRID:AB_2118009) were from Cell Signaling Technologies

(11) Clofazimine inhibits small-cell lung cancer progression by modulating the kynurenine/aryl hydrocarbon receptor axisInternational Journal of Biological MacromoleculesDecember 1, 2024Gunjan Sharma, K.M. Abdullah, Faizan Abul Qais, Parvez Khan, Jesse L. Cox, Tarique Sarwar, Mohd Wasim Nasser, Surinder K. Batra, Jawed A. SiddiquiPARP,WB: 1:1000,Cell Signaling technology,Cat#5625 FoxM1,WB: 1:1000,Cell Signaling technology,Cat#5436 Vimentin,WB: 1:1000,Cell Signaling technology,Cat#5741 AhR,WB: 1:1000,Invitrogen,Cat#MA1–514 Phospho-Erk1/2,WB:

(12) Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes in Triple-Negative Breast CancerCancer ResearchNovember 4, 2024Katrina M. Piemonte, Natasha N. Ingles, Kristen L. Weber-Bonk, Mitchell J. Valentine, Parth R. Majmudar, Salendra Singh, Ruth A. KeriTechnology, Danvers, MA, USA; CST 65890, 1:250), FOXM1(Cell Signaling Technology, Danvers, MA, USA; CST #5436, 1:500), β-actin (Sigma Aldrich #A2228, 1:10,000), Acetyl α-Tubulin (CST5335, 1:500), and Total α-Tubulin

(13) Resistance to FOXM1 inhibitors in breast cancer is accompanied by impeding ferroptosis and apoptotic cell deathBreast Cancer Research and TreatmentNovember 1, 2024Sandeep Kumar, Yvonne Ziegler, Blake N. Plotner, Kristen M. Flatt, Sung Hoon Kim, John A. Katzenellenbogen, Benita S. Katzenellenbogentransferred to nitrocellulose membranes. All antibodies were from Cell Signaling Technology (FOXM1, Cat# 5436; ERα, Cat# 8644; LCN2, Cat# 44,058; GPX4, Cat# 52,455; SLC7A11, Cat# 12,691) except for NUPR1, which

(14) Chromatin accessibility is associated with therapeutic response in prostate cancerOncology LettersOctober 14, 2024Sanghoon Lee, Da Young Lee, Insuk So, Jung Nyeo Chun, Ju-Hong Jeonsaline-0.1% Tween 20 for 1 h at room temperature and were then incubated with anti-FOXM1 (1:1,000; cat. no. 5436S; Cell Signaling Technology, Inc.), anti-caspase-3 (1:1,000; cat. no. 9662S; Cell Signaling Technology,

(15) Rho GTPase activating protein 11A promotes tongue squamous cell carcinoma proliferation and is a transcriptional target of forkhead box M1Journal of dental sciencesOctober 1, 2024Zhang W, Bai X, Liu T, Mao Y, Zhang L, Wang W, Yu H.antibody specifically targets ARHGAP11A (1:1000, PA5-59170, ThermoFisher Scientific), FOXM1 (1:1000, #5436, Cell Signaling Technology, Danvers, MA, USA), GTP-RhoA (1:1000, 26904, NewEast Biosciences, Prussia,

(16) Thiostrepton induces spindle abnormalities and enhances Taxol cytotoxicity in MDA-MB-231 cellsMolecular biology reportsAugust 21, 2024Kuo HH, Yao JS, Yih LH.against cyclin B1 (1:1000, sc-245, Santa Cruz Biotechnology, Inc., Dallas, Texas), FoxM1 (1:1000, #5436, Cell Signaling Technology), HSP70 (1:1000, GTX104126, GeneTex), histone H3 phosphorylated at S10 (1:1000,

(17) Injury-induced Foxm1 expression in the mouse kidney drives epithelial proliferation by a cyclin F-dependent mechanismJCI insightJune 25, 2024Noonan ML, Muto Y, Yoshimura Y, Leckie-Harre A, Wu H, Kalinichenko VV, Humphreys BD, Chang-Panesso M.detection system (GE Healthcare, now Cytiva). Primary antibodies were Foxm1 (Cell Signaling Technology 5436S), phospho-Foxm1 (Cell Signaling Technology 14655), PCNA (Cell Signaling Technology 13110S), MEK1/2 (Cell Signaling Technology

(18) Therapy-induced secretion of spliceosomal components mediates pro-survival crosstalk between ovarian cancer cellsNature communicationsJune 19, 2024Shender VO, Anufrieva KS, Shnaider PV, Arapidi GP, Pavlyukov MS, Ivanova OM, Malyants IK, Stepanov GA, Zhuravlev E, Ziganshin RH, et al.(Abcam, ab177946, 1:1000), TDP1(Сell Signaling, #59710, 1:1000), FOXM1 (Cell Signaling Technology, #5436, 1:1000), RAD51 (Abcam, ab213, 1:200), p53 (Cell Signaling Technology, #2524, 1:1000), TIA1 (Invitrogen,

(19) Tumor microenvironment-induced FOXM1 regulates ovarian cancer stemnessCell death & diseaseMay 28, 2024Battistini C, Kenny HA, Zambuto M, Nieddu V, Melocchi V, Decio A, Lo Riso P, Villa CE, Gatto A, Ghioni M, et al.were incubated overnight at 4 °C with the following primary antibodies: FOXM1 (Cell Signaling, cat# 5436), FAK (Invitrogen, cat# 39-6500), phospho-FAK (Tyr397) (Invitrogen, cat# 700255), YAP (Cell Signaling,

(20) NB compounds are potent and efficacious FOXM1 inhibitors in high-grade serous ovarian cancer cellsJournal of ovarian researchMay 4, 2024Liu C, Vorderbruggen M, Muñoz-Trujillo C, Kim SH, Katzenellenbogen JA, Katzenellenbogen BS, Karpf AR.(Sigma-Aldrich). Primary antibodies included anti- FOXM1 (Cell Signaling Technology, CST, Danvers, MA, USA) (CST #5436, 1:1,000), p-FOXM1 (Thr600) (CST #14655, 1:1,000–1:2,000), AURKB (Abcam, Waltham, MA, USA, #2254, 1:1,000),

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9/11/2015Overexpression of FoxM1 in Glioblastoma, Breast Cancer and Colorectal Cancer bala bhaskarWe are working on FoxM1's role in colorectal cancer and trying to find out the molecular mecanism. This product is user-friendly and allows you to detect your specific band with out any non-... Read Review

FoxM1 (D12D5) XP ® Rabbit mAb

FoxM1 (D12D5) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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FoxM1 (D12D5) XP ® Rabbit mAb from Cell Signaling Technology

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