VCAM-1/CD106 Antibody (6G9)

Product Specs
ItemVCAM-1/CD106 Antibody (6G9) - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $429.00Supplier Page View Company Product Page
Catalog NumberNBP1-47491
TargetVCAM-1/CD106
NCBI Gene AliasesINCAM-100, CD106
ImmunogenThis VCAM-1/CD106 Antibody (6G9) was developed against a purified recombinant fragment of human VCAM-1 expressed in E. coli. [Uniprot: P19320]
Clone6G9
ApplicationsELISA,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunoblotting,Simple Western,Immunocytochemistry/ Immunofluorescence
Quantity0.1 ml (also 0.025 ml)
FormatPBS
HostMouse
ReactivityHuman,Mouse
ClonalityMonoclonal
IsotypeIgG1
Conjugate/TagUnconjugated
NCBI Full Gene Namevascular cell adhesion molecule 1
Concentration1.0 mg/ml
PurityAmmonium sulfate precipitation
Molecular Weight81 kDa
Research AreaCancer, Mesenchymal Stem Cell Markers, Stem Cell Markers
Antibody TypePrimary Antibodies
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Sizes Available: 0.1 ml (also 0.025 ml)

Questions and Answers

Can this VCAM-1 antibody be used for immunohistochemistry on human tissues?

Yes, the VCAM-1/CD106 Antibody (6G9) has been shown to work in immunohistochemistry for human tissue, as referenced in the study by Chen et al. (2015) where it was utilized to assess VCAM-1 expression in human samples.

Is this antibody effective for studying endothelial-to-mesenchymal transition in atherosclerosis?

The VCAM-1/CD106 Antibody (6G9) has been cited in research investigating endothelial-to-mesenchymal transition, particularly in the context of atherosclerosis, as demonstrated in the study by Chen et al. (2015). This suggests its utility in exploring the molecular mechanisms involved in this process.

What applications can I use this antibody for in my research?

This antibody is versatile and can be used in various applications including Western blotting, ELISA, immunocytochemistry, immunofluorescence, immunohistochemistry, and immunoprecipitation, making it suitable for a wide range of experimental setups.

Does this antibody react with both mouse and human samples?

Yes, the VCAM-1/CD106 Antibody (6G9) is reactive with both mouse and human samples, which allows for comparative studies across species in research involving stem cells and vascular biology.

Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Symptoms and clinical course of EHEC O104 infection in hospitalized patients: a prospective single center studyPloS oneJanuary 1, 0001"Ullrich S, Bremer P, Neumann-Grutzeck C, Otto H, Rüther C, von Seydewitz CU, Meyer GP, Ahmadi-Simab K, Röther J, Hogan B, et al."

(2) A microphysiological model of human trophoblast invasion during implantationNature communicationsJanuary 1, 0001"Park JY, Mani S, Clair G, Olson HM, Paurus VL, Ansong CK, Blundell C, Young R, Kanter J, Gordon S, et al."Abcam, catalog # ab11333), Ki67 (37C7-12, Abcam, catalog # ab245113) VCAM-1(6G9, Novus Biologicals, NBP1-47491), and Complement C4 (JM88-13, Thermo Fisher, catalog # MA5-32856) diluted at 1:200 in 1% BSA-containing

(3) The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosisNature communicationsJanuary 1, 0001"Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, Song L, Zhou X, Chen J, Zhou H, et al."p65 (Cell Signaling Technology, #8242T, 1:1,000), ICAM-1 (Sangon, #D221861, 1:1,000), VCAM-1 (Novus, #NBP1-47491, 1:1,000), CD62E (Abcam, #ab18981, 1:1,000), NEMO (given by Dr Wang Ming, 1:1,000), or IκBα (Cell Signaling Technology

(4) Endothelial-to-mesenchymal transition drives atherosclerosis progressionThe Journal of clinical investigationJanuary 1, 0001"Chen PY, Qin L, Baeyens N, Li G, Afolabi T, Budatha M, Tellides G, Schwartz MA, Simons M."Cell Signaling; IB), TGF-βR1 (sc-398, Santa Cruz; IB), β-tubulin (T7816, Sigma-Aldrich; IB), VCAM-1 (NBP1-47491, Novus Biologicals; IHC for human tissue), VCAM-1 (ab19569, abcam; IHC for mouse tissue), VCAM-1 (3540-1, Epitomics;

(5) Smooth Muscle Cell Reprogramming in Aortic AneurysmsCell stem cellJanuary 1, 0001"Chen PY, Qin L, Li G, Malagon-Lopez J, Wang Z, Bergaya S, Gujja S, Caulk AW, Murtada SI, Zhang X, et al."anti-TIMP3,abcam,"Cat# ab39184, RRID:AB_2204971" Mouse monoclonal anti-VCAM-1 (clone 6G9),NOVUS BIOLOGICALS,"Cat# NBP1-47491, RRID:AB_10010443" Rat monoclonal anti-CD90 (clone 778053),R and D Systems,"Cat# MAB7335, RRID:AB_2687967" Rabbit

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