Ape1 (E5Y2C) Rabbit mAb 10519S from Cell Signaling Technology

Product Specs
ItemApe1 (E5Y2C) Rabbit mAb
CompanyCell Signaling Technology
Price $357.00 Inquire
Catalog Number10519S
Quantity100 µl
ApplicationsW, IHC-P, IF-IC
ReactivityH, M, R
TargetAPE1
Molecular Weight34
HostRabbit
NCBI Full Gene Nameapurinic/apyrimidinic endodeoxyribonuclease 1
NCBI Gene AliasesAPE, APE1, APEN, APEX, APX, HAP1, REF1
ClonalityMonoclonal
Research AreaCell Cycle / Checkpoint Control

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) An APE1 Redox Inhibitor Attenuates Pathological Retinal Vascularization by Suppressing FGF2 Angiogenic SignalingInvest Ophthalmol Vis SciMarch 20, 2026Chenfei Yan, Qiangqiang Fu, Jiawei Wang, Qian Fan, Haoran Xu, Rui Zhang, Yan Yuan, Jianqiao Liprimary antibodies overnight at 4°C. Used primary antibodies were rabbit anti-APE1 at a 1:200 dilution (#10519; Cell Signaling Technology, USA), and rabbit anti-FGF2 at a 1:200 dilution (#DF6038; Affinity, China).

(2) Small-molecule RNA therapeutics to target prostate cancerCancer CellMay 12, 2025Duygu Kuzuoglu-Ozturk, Hao G. Nguyen, Lingru Xue, Emma Figueredo, Vishvak Subramanyam, Isabelle Liu, Kenya Bonitto, Ashish Noronha, Adrianna Dabrowska, Janet E. Cowan, et al.,Proteintech Group INC,Cat# 16964-1-AP; RRID: AB_2180894 Rabbit monoclonal anti-Apex1,Cell Signaling Technology,Cat# 10519; RRID: AB_3064913 Mouse monoclonal anti-HIF-1 alpha,Proteintech Group INC,Cat# 66730; RRID: AB_2882080 Rabbit

(3) OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced senescence in human fibroblastsNat CommunJanuary 21, 2025Mariarosaria De Rosa, Ryan P. Barnes, Ariana C. Detwiler, Prasanth R. Nyalapatla, Peter Wipf, Patricia L. Opresko(Enzo Life Science #ALX-804-220-R100, WB dilution 1:500), anti-APE1 rabbit monoclonal (Cell Signaling #10519S, WB dilution 1:1000), anti-Cyclin A mouse monoclonal (Santa Cruz #sc-271682, WB dilution 1:200). Flow Cytometry Analysis

(4) Flap endonuclease 1 repairs DNA-protein cross-links via ADP-ribosylation-dependent mechanismsScience advancesJanuary 10, 2025Sun Y, Jenkins LM, El Touny LH, Zhu L, Yang X, Jo U, Escobedo L, Maity TK, Saha LK, Uribe I, et al.monoclonal, Santa Cruz Biotechnology, 13563; anti-APE1, rabbit monoclonal, Cell Signaling Technology, 10519; anti-EXO1, rabbit polyclonal, Abcam, 95068, anti-DNA2, rabbit polyclonal, Abcam, 96488; anti-MRE11,

(5) Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapyCellOctober 17, 2024Chhabra Y, Fane ME, Pramod S, Hüser L, Zabransky DJ, Wang V, Dixit A, Zhao R, Kumah E, Brezka ML, et al.,Cell Signaling,5246;RRID:AB_10694683 H3K27me3,Cell Signaling,9733;RRID:AB_2616029 APE1,Cell Signaling,10519;RRID:AB_3064913 SOD1,Cell Signaling,37385;RRID:AB_3073954 SOD2,Cell Signaling,13141;RRID:AB_2636921 SOD3,Santa Cruz Biotechnology

(6) A Spatio-Temporal-Dependent Requirement of Sonic Hedgehog in the Early Development of Sclerotome-Derived Vertebrae and RibsInternational journal of molecular sciencesMay 21, 2024Kahane N, Dahan-Barda Y, Kalcheim C.Molecular Probes, Eugene, OR, USA, https://www.thermofisher.com/il/en/home/brands/molecular-probes.html, #10519). Monoclonal antibodies against Pax7 (PAX7-s, 1:20, DSHB, University of Iowa), phosphorylated Smad 1-5-8

(7) OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescencebioRxiv : the preprint server for biologyApril 11, 2023Rosa M, Barnes RP, Nyalapatla PR, Wipf P, Opresko PL.(Sigma A1106; 1:500 WB); PAR (10H) (Enzo ALX-804-220-R100, 1:500 WB, 1:100 IF), APE1 (Cell Signaling 10519S; 1:1000 WB); Cyclin A (Santa Cruz sc-271682; 1:500 WB). Recombinant DNA pLentiCRISPR v2 gRNA, OGG1

(8) MYC oncogene elicits tumorigenesis associated with embryonic, ribosomal biogenesis, and tissue-lineage dedifferentiation gene expression changesOncogeneNovember 1, 2022Sullivan DK, Deutzmann A, Yarbrough J, Krishnan MS, Gouw AM, Bellovin DI, Adam SJ, Liefwalker DF, Dhanasekaran R, Felsher DW.clone SolA15, Invitrogen, Cat# 13-5698-82), Apex1 (1:100, clone E5Y2C, Cell Signaling Technology, Cat# 10519), biotinylated anti-rabbit (1:300, Vectastain ABC kit, Vector Laboratories, Cat# BA-1000). DAB staining

(9) Early recruitment of PARP-dependent m(8)A RNA methylation at DNA lesions is subsequently accompanied by active DNA demethylationRNA biologyJanuary 1, 2022Legartová S, Svobodová Kovaříková A, Běhalová Suchánková J, Polášek-Sedláčková H, Bártová E.USA), anti-RIF1 (#GTX131889, GeneTex, Taiwan), anti-PARP1 (#A2432, ABclonal, USA), and anti-APE1 (#10519S, Cell Signalling Technology, USA). The indicated primary antibodies were diluted at 1:100 in blocking

(10) Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progressionCell metabolismDecember 2, 2014Dentice M, Ambrosio R, Damiano V, Sibilio A, Luongo C, Guardiola O, Yennek S, Zordan P, Minchiotti G, Colao A, et al.antibody is described elsewhere (Huang et al., 2003). Anti-Desmin antibody was from MP Biomedicals (#10519). Anti-total Akt was from Upstate, and anti-pAkt and anti-PARP were from Cell Signaling Technology.

(11) Perivascular Mural Cells of the Mouse Choroid Demonstrate Morphological Diversity That Is Correlated to Vasoregulatory FunctionPLoS ONEJanuary 4, 2013Audrey B. Condren, Anil Kumar, Pradeep Mettu, Katharine J. Liang, Lian Zhao, Jen-yue Tsai, Robert N. Fariss, Wai T. Wongα-SMA (1∶200, Sigma), NG2 (1∶200; Upstate Cell Signaling Solutions, CA) and anti-desmin (1∶20; Cat # 10519, MP Biomedicals, Solon, OH) for labeling choroidal smooth muscle cells and pericytes. Secondary antibodies,

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Ape1 (E5Y2C) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Ape1 (E5Y2C) Rabbit mAb from Cell Signaling Technology

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