DNA Cytosine Modification Antibody Sampler Kit from Cell Signaling Technology

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DNA Cytosine Modification Antibody Sampler Kit

Description

5-Methylcytosine (5-mC) (D3S2Z) Rabbit mAb recognizes endogenous levels of 5-methylcytosine. 5-Hydroxymethylcytosine (5-hmC) (HMC31) Mouse mAb recognizes endogenous levels of 5-hydroxymethylcytosine. 5-Formylcytosine (5-fC) (D5D4K) Rabbit mAb recognizes transfected levels of 5-formylcytosine. 5-Caroxylcytosine (5-caC) (D7S8U) Rabbit mAb recognizes transfected levels of 5-methylcytosine. These antibodies have been validated using ELISA and dot blot, and cross-reactivity was not observed with other marks. Many cells and tissues contain very low endogenous levels of 5-hmC, 5-fC, and 5-caC that may fall below the detection limits of these antibodies