beta-Galactosidase (E2U2I) Rabbit mAb 27198S from Cell Signaling Technology

Product Specs
Itembeta-Galactosidase (E2U2I) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number27198S
Quantity100 µl
ApplicationsW, IF-IC
ReactivityH, M, R, Hm, Mk
TargetBeta Galactosidase
IsotypeIgG
HostRabbit
NCBI Full Gene Namegalactosidase beta 1
NCBI Gene AliasesEBP, ELNR1, MPS4B
ClonalityMonoclonal
Research AreaGlucose / Energy Metabolism
Molecular Weight65

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Assessment of sub-chronic toxicity and anti-aging effects of a solid self-microemulsifying drug delivery system of Kaempferia parviflora extract in a D-galactose-induced rat modelPharmaceutical BiologyDecember 31, 2026Somsuda Somintara, Waraporn Sakaew, Sarunya Tuntiyasawasdikul, Peera Tabboon, Catheleeya Mekjaruskul, Jenjiralai Phanphak, Choowadee Pariwatthanakun, Bungorn Sripanidkulchai, Tawut Rudtanatipmouse-anti-Sirt-1 (cat. no. 8469S, Cell Signaling Technology Inc., USA), rabbit-anti-SA-β-gal (cat. no. 27198S, Cell Signaling Technology Inc., USA), rabbit-anti-TNF-α (cat. no. 3707S, Cell Signaling Technology

(2) Numb mitigates intestinal epithelial cell senescence induced by radiation through a PLK1-dependent pathwayScientific ReportsMarch 27, 2026Yongtao Yang, Xiao Hu, Yuwei Pan, Wen Ji, Tao Liu, Xi ZhengCruz, sc-517348), Cyclin B (Santa Cruz, sc-166210), Plk1 (Abcam, ab12157) and β-galactosidase (CST, #27198) were incubated with the membranes at 4 °C overnight, followed by incubation with the respective secondary

(3) Conditional BCL-2 Expression in Fibroblasts Promotes Persistent Pulmonary Fibrosis which is Reversible by Therapeutic BCL-2 InhibitionNature CommunicationsFebruary 28, 2026Elizabeth F. Redente, Tengyao Song, Nomin Javkhlan, Benjamin L. Edelman, Daniel G. Foster, Jasmine A. Wilson, Sangeeta Chakraborty, Joseph C. Cooley, Rohit Gaurav, Satria Saguthi, et al.#ab211542 rabbit, 1:100), p21WAF (Abcam #ab188224 rabbit, 1:250), β-galactosidase (Cell Signaling #27198 rabbit, 1:200), CCSP (Seven Hills Bioreagents #WRAB-3950 rabbit, 1:200, Cincinnati, OH), pro-SPC (Millipore

(4) Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicityInternational Journal of OncologyFebruary 24, 2026Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz[PA5-32396, Invitrogen/Thermo Fisher Scientific; Carlsbad, USA], Galactosidase beta (E2U2I) (cat. no. 27198, Cell Signaling Technology, Inc.), GAPDH (14C10; cat. no. 2118S; Cell Signaling Technology, Inc.), H2AX

(5) Interleukin-17A Orchestrates Lung Injury and Remodeling Through p53 and uPA System CrosstalkInternational Journal of Molecular SciencesFebruary 14, 2026Durgesh Nandini Das, Akarsha Balnadupete, Rashmi Shetty, Venkadesa Perumal Gopu, Rushil Sajjan, Yashodhar P. Bhandary, Amarnath S. Marudamuthu, Christian Oliver, Aarav Patel, Aryan Patel, et al.Technology,3700,1:1000, 9,IL-17A,Abcam,ab79056,1:1000,1:500 10,IL-17RA,Abcam,ab180904,1:1000, 11,TRF1,Abcam,ab1423,1:1000,1:500 12,TRF2 (D1Y5D) rabbit mAb,CST,13136S,1:1000,1:500 13,β-Gal,CST,27198s,1:1000, 14,Anti-Col-1 mAb,Southern Biotech,#1340-01,1:1000, 15,Anti-FN Ab,Molecular Innovations,#ASMFBN,1:1000, 16,PNUTS,CST,14171,1:1000, 17,PP2Ac,CST,2259S,1:1000, 18,pATM,Millipore,05-740Sp,1:1000, 19,MDM2,Abcam,ab226939,1:1000, 20,ATM,Millipore,05513,1:1000, 21,Anti-αSMA

(6) FTO-dependent m6A methylation mediates gestational diabetes mellitus-induced offspring cardiac senescent hypertrophy and dysfunctioniScienceJanuary 16, 2026Wansu Yu, Yong Li, Siyi Jiang, Jia Tian, Shu-Wei Sun, Lubo Zhang, DaLiao Xiao,Cell Signaling Technology,Cat# 14796; RRID: AB_271625 Rabbit β-Galactosidase,Cell Signaling Technology,Cat# 27198; RRID: AB_2798940 Rabbit Ki-67,Cell Signaling Technology,Cat# 9129; RRID: AB_2687446 Donkey Anti-Rabbit

(7) Therapeutic potential of recombinant human collagen XVII in blue light-induced skin photoaging: preserving epidermal-dermal structural integrity and functional homeostasisFrontiers in bioengineering and biotechnologyJanuary 1, 2026Wang X, Zhang L, Li Q, Ao J, Zhang X, Yang X, Li J, Sui S, Ge G, Li H, et al.were then incubated overnight at 4 °C with primary antibodies against SA-β-gal (Cell signaling, Cat#27198T, 1:100), IL-6 (Abcam, Cat#Ab9324, 1:100), TNF-α (Abcam, Cat#Ab307164, 1:100), COL4A1 (Abcam, Cat#Ab6586,

(8) Correlation of molecular and cellular signatures in primary skeletal muscle satellite cells derived from lean and diet-induced obese miceIn Vitro Cellular & Developmental Biology - AnimalNovember 21, 2025Florian Krabichler, Andreas Mayr, Kristin Seichter, Maryam Keshavarz, Kevin Knäbel, Kerstin Stemmer, Marco Koch, Laura Steingruberab129815","Rabbit, polyclonal","WB, 1:1000" ß-galactosidase 1 (GLB1),"Cell Signaling, Danvers, MA; 27198S","Rabbit, monoclonal","WB, 1:1000" CD56/NCAM1,"Abcam, Cambridge, UK; ab220360","Mouse, monoclonal","WB,

(9) Tet Methylcytosine Dioxygenase 3 Promotes Cardiovascular Senescence by DNA 5-Hydroxymethylcytosine-Mediated Sp1 Transcription Factor ExpressionMedComm (2020)June 19, 2025Yanqi Dang, Jing Ma, Shuang Ling, Shurong Wang, Huining Guo, Jun Liu, Guang Ji, Jin-Wen Xuab26350, Abcam), SP1 (1:100, A19649, ABclonal), TET3 (1:200, GTX‐121453, GENETEX), β‐galactosidase (1:100, 27198, CST), p16 (1:100, sc‐1661, Santa Cruz), p21 (1:100, sc‐6246, Santa Cruz), and p53 (1:100, 2524, CST).

(10) Comprehensive secretome profiling and CRISPR screen identifies SFRP1 as a key inhibitor of epidermal progenitor proliferationCell death & diseaseMay 3, 2025Cheng B, Peng SI, Jia YY, Tong E, Atwood SX, Sun BK.software. Immunofluorescence staining was also performed on cells (for β-galactosidase, Cell Signaling, cat# 27198 and cleaved caspase-3, Cell Signaling, cat#9664) or colonies (for Ki67) seeded on chamber slides. RNA-sequencing Primary

(11) PrP(C) Glycoprotein Is Indispensable for Maintenance of Skeletal Muscle Homeostasis During AgingJournal of cachexia, sarcopenia and muscleFebruary 1, 2025Liu W, Kieu TTT, Wang Z, Sim HJ, Lee S, Lee JC, Park Y, Kim SH, Kook SH.Parkin (SCBT, sc‐32 282, USA); PRNP (Cell Signaling, #14025, USA); β‐Galactosidase (Cell Signaling, #27198, USA); P16 (SCBT, sc‐759, USA); Pax‐7 (SCBT, sc‐81 648, USA); MyoD (SCBT, sc‐377 460, USA); Myogenin

(12) Exposure of Young Mice to Atmospherically Relevant PM2.5 Has Sex-Dependent Long-Lasting Impacts on the Skeletal Muscle SystemAging DisDecember 16, 2024Wenduo Liu, Zilin Wang, Min-Hye Kim, Yu Gu, Hyun-Jaung Sim, Jeong-Chae Lee, Sung-Ho Kook, Sang Hyun Kimwith the following primary antibodies: Pax-7 (SCBT, sc-81648, USA), β-galactosidase (Cell Signaling, #27198, USA), and P16 (SCBT, sc-759, USA). After three washes with PBS-T, the samples and secondary antibodies

(13) Exposure of Young Mice to Atmospherically Relevant PM2.5 Has Sex-Dependent Long-Lasting Impacts on the Skeletal Muscle SystemAging DisDecember 2, 2024Wenduo Liu, Zilin Wang, Min-Hye Kim, Yu Gu, Hyun-Jaung Sim, Jeong-Chae Lee, Sung-Ho Kook, Sang Hyun Kimwith the following primary antibodies: Pax-7 (SCBT, sc-81648, USA), β-galactosidase (Cell Signaling, #27198, USA), and P16 (SCBT, sc-759, USA). After three washes with PBS-T, the samples and secondary antibodies

(14) Deciphering the role of rapamycin in modulating decidual senescence: implications for decidual remodeling and implantation failureJournal of assisted reproduction and geneticsSeptember 1, 2024Kendirci-Katirci R, Sati L, Celik-Ozenci C.DIO2 (Goat, 1:100, Invitrogen, PA5-18659, USA), and β-galactosidase (Rabbit, 1:400, Cell Signaling, #27198, USA) diluted in 5% BSA-PBS. Rabbit IgG and goat IgG served as the isotype control for appropriate primary

(15) Alternative splicing of BAZ1A in colorectal cancer disrupts the DNA damage response and increases chemosensitizationCell death & diseaseAugust 7, 2024Mohan N, Johnson GS, Tovar Perez JE, Dashwood WM, Rajendran P, Dashwood RH.antibody to pH2AX Ser139 (#9718, Cell Signaling), BAZ1A (#A301-318A, Bethyl labs), β-galactosidase (#27198, Cell Signaling) or H3 (#39064, Active Motif) followed by secondary antibody coupled to AlexaFluor 555

(16) Single-cell transcriptomic Atlas of aging macaque ocular outflow tissuesProtein & CellJuly 20, 2024Jian Wu, Chaoye Wang, Shuhui Sun, Tianmin Ren, Lijie Pan, Hongyi Liu, Simeng Hou, Shen Wu, Xuejing Yan, Jingxue Zhang, et al.by Image J 1.52a software. The antibodies against APOE (13366) and β-galactosidase (i.e., SA-β-gal, 27198) were obtained from Cell Signaling Technology (Danvers, MA, USA). Antibodies against CLU (12289-1-AP),

(17) Co‐targeting SKP2 and KDM5B inhibits prostate cancer progression by abrogating AKT signaling with induction of senescence and apoptosisThe ProstateJune 1, 2024LaKendria K. Brown, Thanigaivelan Kanagasabai, Guoliang Li, Sherly I. Celada, Jelonia T. Rumph, Samuel E. Adunyah, LaMonica V. Stewart, Zhenbang Chenanti-pAKT Ser473,1: 1000,Cell Signaling,9271S 1° rabbit anti-β-Galactosidase,1: 1000,Cell Signaling,27198 1° rabbit anti-Bax,1: 1000,Cell Signaling,2772 1° mouse anti-Bcl2,1: 1000,Cell Signaling,3498 1°

(18) Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse modelAging (Albany NY)May 30, 2024Lucie Aumailley, Marie Julie Dubois, André Marette, Michel Lebelprotein (p16 INK4A (E5F3Y) #29271) and senescence associated-β-galactosidase (β-Galactosidase (E2U2I) #27198S) from Cell Signaling (Whitby, ON, Canada). Coomassie blue dye was used to stain proteins in SDS-PAGE gels

(19) A renal clearable fluorogenic probe for in vivo β-galactosidase activity detection during aging and senolysisNature CommunicationsJanuary 26, 2024Sara Rojas-Vázquez, Beatriz Lozano-Torres, Alba García-Fernández, Irene Galiana, Ana Perez-Villalba, Pablo Martí-Rodrigo, M. José Palop, Marcia Domínguez, Mar Orzáez, Félix Sancenón, et al.membranes, blocked with 5% nonfat milk and incubated overnight with antibodies to β-Gal (Cell Signaling, #27198, diluted 1:1000) and to GAPDH (Cell Signaling, #2118, diluted 1:3000) as a loading control. Then, membranes

(20) The Triterpenoid Nrf2 Activator, CDDO-Me, Decreases Neutrophil Senescence in a Murine Model of Joint DamageInternational journal of molecular sciencesMay 15, 2023Amirova KM, Dimitrova PA, Leseva MN, Koycheva IK, Dinkova-Kostova AT, Georgiev MI.Cell Signaling Technology, Leiden, The Netherlands) or anti-β-galactosidase antibody (dilution 1:200, #27198; clone E2U2I, Cell Signaling Technology, Leiden, The Netherlands) or isotype control antibodies (Cell

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beta-Galactosidase (E2U2I) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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beta-Galactosidase (E2U2I) Rabbit mAb from Cell Signaling Technology

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