GFRα-1 (E-11) Antibody sc-271546 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemGFRα-1 (E-11) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-271546
ClonalityMonoclonal
ApplicationsWB, IP, IF, IHC(P), ELISA
NCBI Gene AliasesRHDA4, GDNFR-alpha-1, GDNFRA, GFR-ALPHA-1, RET1L, TRNR1, GFRalpha-1, GDNFR, RETL1
Antibody TypePrimary Antibodies
CloneE-11
Conjugate/TagUnconjugated
Reactivitymouse, rat, human
Quantity200 µg/ml
Hostmouse
NCBI Full Gene NameGDNF family receptor alpha 1, glial cell line derived neurotrophic factor family receptor alpha 1
TargetGFRalpha-1
FormatPurified
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Effect of Extracellular Matrix Derived from Porcine Tissue on Stemness of Porcine Spermatogonial Stem CellsInt J Mol SciOctober 13, 2025Donghyeon Kim, Min-Gi Han, Yoseop Jeon, Hyoyoung Maeng, Youngseok Choi, Kwonho Hong, Jeong Tae Do, Hyuk Song1% BSA (primary antibodies: PGP9.5 [7863-1004], Invitrogen; PLZF [PA5-29213], R&D Systems; GFRα-1 [sc-271546], Santa Cruz Biotechnology, Dallas, TX, USA; and β-actin [SC-47778], Santa Cruz Biotechnology). After

(2) Wu Zi Yan Zong Wan Improves Triptolide-Induced Testicular Spermatogenic Dysfunction Through the Spermatogenic Microenvironment and the PLCγ/PKC PathwayAm J Mens HealthOctober 2, 2025Lei Zhang, Binghao Bao, Weizhen Wu, Haolang Wen, Suyan Tong, Xueyan Wang, Baoxing LiuUSA)SCF: Santa Cruz Biotechnology (Cat. No. sc-13126; TX, USA)GFRα1: Santa Cruz Biotechnology (Cat. No. sc-271546; TX, USA)C-kit: Abcam (Cat. No. ab256345; dilution; Cambridge, UK)CSF1R: Proteintech (Cat. No. 25949-1-AP;

(3) Reactive Astrocytes Release GDNF to Promote Brain Recovery and Neuronal Survival Following Ischemic StrokeNeurochemical researchMarch 14, 2025Zhang Z, Zhang N, Ding S.No. SC-13147, Santa Cruz Biotechnology), a mouse anti-GFR α1 monoclonal antibody (1:1000, Cat. No. SC-271546, Santa Cruz Biotechnology), a rabbit anti-RET monoclonal antibody (1:500, Cat. No. 3223, Cell Signaling),

(4) GDNF/GFRA1 signaling contributes to chemo- and radioresistance in glioblastomaScientific reportsJuly 31, 2024Avenel ICN, Ewald JD, Ariey-Bonnet J, Kristensen IH, Petterson SA, Thesbjerg MN, Burton M, Thomassen M, Wennerberg K, Michaelsen SR, et al.retrieval was completed, and the sections were stained with both Hematoxylin (Roche Diagnostics) and GFRA1 (sc-271546 E-11, 1:800, Santa Cruz Biotechnology). Stained slides were digitalized with the Vectra Polaris Automated

(5) Electroacupuncture improves gastrointestinal motility through a central-cholinergic pathway-mediated GDNF releasing from intestinal glial cells to protect intestinal neurons in Parkinson's disease ratsNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeuticsJuly 1, 2024Zhang C, Chen T, Fan M, Tian J, Zhang S, Zhao Z, Liu X, Ma H, Yang L, Chen Y.Hydrolase,1:500,mouse,"Santa Cruz, sc-25269" GDNF,1:500,mouse,"Santa Cruz, sc-13147" GFRα1,1:500,mouse,"Santa Cruz, sc-271546" AKT,1:1000,Rabbit,"Boster, A00024-2" phosphorylation-AKT,1:1000,Rabbit,"Boster, A00024Y437" GAPDH,1:1000,Rabbit,"Boster,

(6) Prediction of cell-cell communication patterns of dorsal root ganglion cells: single-cell RNA sequencing data analysisNeural Regeneration ResearchJune 1, 2024Yanna Lian, Cheng Wu, Li Liu, Xiangyao Liprimary antibodies (rabbit anti-A2B antibody, Cat# sab4500429, Sigma-Aldrich; mouse anti-GFRα-1, Cat#sc-271546, Santa Cruz Biotechnology, Santa Cruz, CA, USA; both 1:100) overnight at 4°C. Slides were washed in

(7) Evaluation of Apoptosis-Related Genes and Hormone Secretion Profiles Using Three Dimensional Culture System of Human Testicular OrganoidsGalen Medical JournalAugust 26, 2023Aghbibi Nikmahzar, Aghbibi Nikmahzar, Morteza Khadivi, Morteza Jahanshahi, Masoomeh Dehghan Tarazjani, Mehrdad Jahanshahi, Yasaman Shabani, Yasaman Abbasifixed cells were treated with anti-GFRα-1 (sc-28319, Santa Cruz Biotechnology, USA) and anti-PLZF (sc-271546, Santa Cruz Biotechnology, USA) primary antibodies at 1:100 concentrations and 37 °C for 2 h.and was

(8) Evaluation of Apoptosis-related Genes and Hormone Secretion Profiles Using Three Dimensional Culture System of Human Testicular OrganoidsGalen Med JAugust 26, 2023Aghbibi Nikmahzar, Farnaz Khadivi, Morteza Koruji, Mehrdad Jahanshahi, Masoomeh Dehghan Tarazjani, Maryam Shabani, Yasaman Abbasi, Mehdi Abbasifixed cells were treated with anti-GFRα-1 (sc-28319, Santa Cruz Biotechnology, USA) and anti-PLZF (sc-271546, Santa Cruz Biotechnology, USA) primary antibodies at 1:100 concentrations and 37 °C for 2 h.and was

(9) Dissecting the spermatogonial stem cell niche using spatial transcriptomicsCell reportsJuly 25, 2023Rajachandran S, Zhang X, Cao Q, Caldeira-Brant AL, Zhang X, Song Y, Evans M, Bukulmez O, Grow EJ, Nagano M, et al.Anti-VWF antibody (1:100, 66682-1-Ig, Proteintech), mouse anti-GFRa1 Alexa Fluor 647 antibody (1:100, sc-271546 AF647, Santa Cruz Biotechnology) and Alexa Fluor 488-, 594-, and 647-conjugated secondary antibodies

(10) A 1-kb human CDCA8 promoter directs the spermatogonia-specific luciferase expression in adult testisGeneMay 25, 2023Wu Y, Zeng S, Miao C, Wu H, Xu X, Chen L, Lu G, Lin G, Dai C.

(11) Kinome Reprogramming Is a Targetable Vulnerability in ESR1 Fusion-Driven Breast CancerCancer ResApril 18, 2023Xuxu Gou, Beom-Jun Kim, Meenakshi Anurag, Jonathan T. Lei, Meggie N. Young, Matthew V. Holt, Diana Fandino, Craig T. Vollert, Purba Singh, Mohammad A. Alzubi, et al.antibody (Abcam, cat# ab51103, RRID:AB_870738, 1:500), GFRα-1 antibody (Santa Cruz Biotechnology, cat# sc-271546, RRID:AB_10649373, 1:1,000), and GAPDH (Santa Cruz Biotechnology, cat# sc-47724, RRID: AB_627678, 1:5,000).

(12) Improving the process of spermatogenesis in azoospermic mice using spermatogonial stem cells co-cultured with epididymosomes in three-dimensional culture systemLife sciencesDecember 1, 2022Rahbar M, Asadpour R, Azami M, Mazaheri Z, Hamali H.

(13) The kinase PLK1 promotes the development of Kras/Tp53-mutant lung adenocarcinoma through transcriptional activation of the receptor RETScience signalingOctober 4, 2022Kong Y, Allison DB, Zhang Q, He D, Li Y, Mao F, Li C, Li Z, Zhang Y, Wang J, et al.(12373) were from Cell Signaling Technology. Antibodies against p-ERK (sc7383), ERK (sc514302), GFRα−1 (sc271546) and GFRα−3 (sc-398618) were from Santa Cruz Biotechnology. Antibodies to Ki67 (ab16667) and TTF-1 (ab133737)

(14) Activation of GDNF-ERK-Runx1 signaling contributes to P2X3R gene transcription and bone cancer painiScienceSeptember 16, 2022Yuan ZL, Liu XD, Zhang ZX, Li S, Tian Y, Xi K, Cai J, Yang XM, Liu M, Xing GG.4370S Rabbit anti-ERK1/2,Cell Signaling Technology,Cat# 4695S Mouse anti-GFRα1,Santa Cruz Biotechnology,Cat#sc-271546 Mouse anti-GAPDH,ZSGB-Bio,Cat# TA-08 Anti-GDNF antibody,Abcam,Cat# ab28956 FITC-conjugated Bandeiraea

(15) GATA-1 mutation alters the spermatogonial phase and steroidogenesis in adult mouse testisMolecular and cellular endocrinologyFebruary 15, 2022Gonçalves MFF, Lacerda SMDSN, Lara NLEM, Oliveira CFA, Figueiredo AFA, Brener MRG, Cavalcante MA, Santos AK, Campolina-Silva GH, Costa VV, et al.

(16) Astaxanthin Relieves Busulfan-Induced Oxidative Apoptosis in Cultured Human Spermatogonial Stem Cells by Activating the Nrf-2/HO-1 pathwayReproductive sciences (Thousand Oaks, Calif.)February 1, 2022Afzali A, Amidi F, Koruji M, Nazari H, Gilani MAS, Sanjbad AS.

(17) Interaction of transcription factor AP-2 gamma with proto-oncogene PELP1 promotes tumorigenesis by enhancing RET signalingMolecular oncologyApril 1, 2021Liu J, Liu Z, Li M, Tang W, Pratap UP, Luo Y, Altwegg KA, Li X, Zou Y, Zhu H, et al.contamination, and STR DNA profiling of the cells was used to confirm identity. The TFAP2C (sc‐12762) and GFRA1 (sc‐271546) antibodies were purchased from Santa Cruz Biotechnology (Dallas, TX, USA). The PELP1 antibody (A300‐180A)

(18) The systemic administration of neural stem cells expressing an inducible and soluble form of growth arrest specific 1 inhibits mammary gland tumor growth and the formation of metastasesCytotherapyMarch 1, 2021Romero-Trejo D, Mejía-Rodríguez R, Sierra-Mondragón E, Navarrete A, Pérez-Tapia M, González RO, Segovia J.

(19) Involvement of Cytokines and Hormones in the Development of Spermatogenesis In Vitro from Spermatogonial Cells of Cyclophosphamide-Treated Immature MiceInternational journal of molecular sciencesFebruary 7, 2021Solomon R, AbuMadighem A, Kapelushnik J, Amano BC, Lunenfeld E, Huleihel M.1:100), polyclonal rabbit anti-mouse CD9 (Santa Cruz; 1:100), monoclonal mouse anti-mouse GFRα-1 (Santa Cruz, sc-271546; 1:50), monoclonal mouse anti-mouse α-6-INTEGRIN (Santa Cruz, 1:50), monoclonal mouse anti-mouse CD9

(20) Eif2s3y Promotes the Proliferation of Spermatogonial Stem Cells by Activating ERK SignalingStem cells internationalJanuary 1, 2021Zhang M, Li N, Liu W, Du X, Wei Y, Yang D, Zhou Z, Ma F, Peng S, Zhang S, et al.Santa Cruz Biotechnology, CA, USA), rabbit anti-STRA8 (1 : 200; ab49602, Abcam, Cambridge, UK), mouse anti-GFRa1 (1 : 200; sc-271546, Santa Cruz Biotechnology, CA, USA), rabbit anti-SOX9 (1 : 200; ab185230, Abcam, Cambridge, UK), and

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GFRα-1 (E-11) Antibody

GFRα-1 (E-11) Antibody from Santa Cruz Biotechnology, Inc.

Santa Cruz Biotechnology, Inc.

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GFRα-1 (E-11) Antibody from Santa Cruz Biotechnology, Inc.

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