Human IL-22 R alpha 1 Antibody AF2770 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman IL-22 R alpha 1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF2770
NCBI Gene AliasesIL22R, IL22R1, CRF2-9
ApplicationsBlocking,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization
IsotypeIgG
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Rat
HostGoat
TargetIL-22 R alpha 1
NCBI Full Gene Nameinterleukin 22 receptor subunit alpha 1
ClonalityPolyclonal
ImmunogenChinese hamster ovary cell line CHO-derived recombinant human IL-22 R alpha 1, Pro18-Thr228, Accession # Q8N6P7
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Interleukin-22 regulates B3GNT7 expression to induce fucosylation of glycoproteins in intestinal epithelial cellsThe Journal of biological chemistryFebruary 1, 2022Carroll DJ, Burns MWN, Mottram L, Propheter DC, Boucher A, Lessen GM, Kumar A, Malaker SA, Xing C, Hooper LV, et al.rhIL-22 (R&D Systems) for 4 h. In additional experiments, 5 μg/ml IL22Rα1 blocking antibody (Cat no. AF2770) or isotype control (R&D Systems) was also added prior to the addition of rhIL-22. Flow cytometry analysis Enteroids

(2) Crystal Structure of the Labile Complex of IL-24 with the Extracellular Domains of IL-22R1 and IL-20R2Journal of immunology (Baltimore, Md. : 1950)October 1, 2018Lubkowski J, Sonmez C, Smirnov SV, Anishkin A, Kotenko SV, Wlodawer A.anti-IL-24, cat# AF1965; anti IL-20R1, cat# AF1176; anti-IL-20R2, cat# AF1788 and anti-IL-22R1, cat# AF2770 (all from R&D Systems); as well as anti-Penta-His-tag, cat# 34660 (Qiagen). Electrophoretic mobility shift assay (EMSA

(3) Interleukin-22 participates in the inflammatory process of vitiligoOncotargetDecember 12, 2017Dong J, An X, Zhong H, Wang Y, Shang J, Zhou J.IL-22 receptor signaling The cells were pretreated with either rabbit anti-human IL-22R antibody (AF2770; R&D systems) or with the isotype control (AB-108-C; R&D systems) at a concentration of 50 μg/ml for

(4) IL‑22 expression is increased variedly in the initial phase, onset and chronic phase of a pristane‑induced arthritis rat modelMolecular medicine reportsAugust 1, 2017Hou W, Wang B, Zhou Y, Xu K, Meng L, Zhu W, Jiang C, Xu P, Lu S.1:200 dilution) from Santa Cruz Biotechnology, Inc. (Dallas, TX USA) and goat anti-IL-22R1 (cat. no. AF2770; 1:200 dilution) from R&D Systems, Inc. (Minneapolis, MN, USA). Biotin conjugated secondary antibodies

(5) Interleukin-22 Might Act as a Double-Edged Sword in Type 2 Diabetes and Coronary Artery DiseaseMediators of inflammationJanuary 1, 2016Gong F, Wu J, Zhou P, Zhang M, Liu J, Liu Y, Lu X, Liu Z.IL-22R1 Signaling To block IL-22R1 in HUVECs, the cells were incubated with human IL-22R1 antibody (AF2770; R&D systems, US) at a concentration of 8 μg/mL for 1 h prior to the addition of IL-22 (PeproTech, US)

(6) IL-22 negatively regulates Helicobacter pylori-induced CCL20 expression in gastric epithelial cellsPloS oneJanuary 1, 2014Chen JP, Wu MS, Kuo SH, Liao F.IL-22 receptor AGS cells were pretreated with 2 µg/ml of a neutralizing antibody against IL-22R1 (AF2770; R&D Systems, Minneapolis, MN) for 1 h before being infected with H. pylori in the absence or presence

(7) IL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cellsRespiratory researchNovember 1, 2013Johnson JR, Nishioka M, Chakir J, Risse PA, Almaghlouth I, Bazarbashi AN, Plante S, Martin JG, Eidelman D, Hamid Q.Biosciences, Lincoln, NE). Blots were then incubated with a goat anti-human IL-22 receptor antibody (1 μg/ml, AF2770, R&D Systems, Minneapolis, MN), a mouse anti-human E-cadherin antibody (1:600, ab1416, Abcam, Cambridge,

(8) IL-22 suppresses IFN-γ-mediated lung inflammation in asthmatic patientsThe Journal of allergy and clinical immunologyFebruary 1, 2013Pennino D, Bhavsar PK, Effner R, Avitabile S, Venn P, Quaranta M, Marzaioli V, Cifuentes L, Durham SR, Cavani A, et al.anti-CD3 (UCHT1) and anti-CD28 (CD28.2; both from BD Bioscience), anti–IFN-γR1 (MAB6732), anti–IL-22Rα1 (AF2770), mouse IgG1 (MAB002), and polyclonal goat IgG (AB-108-C; all from R&D Systems). Isolation and expansion

(9) IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expressionEuropean journal of immunologyOctober 1, 2009Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, Tokumaru S, Okazaki H, Sayama K, Hashimoto K.

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IL-22 R alpha 1 Antibody

IL-22 R alpha 1 Antibody

IL-22 R alpha 1 Antibody

Human IL-22 R alpha 1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (9)

Reviews

Human IL-22 R alpha 1 Antibody from R&D Systems, a Bio-Techne Brand

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