The HTATIP2 antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human antigen. The HTATIP2 antibody has been shown to work in the following applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy