Rabbit Anti-Caldesmon, HMW Antibody MBS4381353 from MyBioSource.com

Product Specs
ItemRabbit Anti-Caldesmon, HMW Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4381353
ClonalityPolyclonal
Format200ug/ml of Ab Purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ApplicationsImmunohistochemistry (IHC) Paraffin
SpeciesRabbit
TargetCaldesmon, HMW
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
NCBI Full Gene Namecaldesmon 1
NCBI Gene AliasesCDM, HCAD, NAG22, L-CAD, LCAD, H-CAD
Conjugate/TagUnconjugated
ReactivityHu, Rt
IsotypeIgG
Molecular Weight150kDa
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)

Specifications/Features

Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120'150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70'80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction

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