Rabbit Anti-Lambda Light Chain Antibody MBS4380765 from MyBioSource.com

Product Specs
ItemRabbit Anti-Lambda Light Chain Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380765
SpeciesRabbit
TargetLambda Light Chain (B-Cell Marker)
NCBI Gene AliasesIGL@, IGLC6
ReactivityHuman (Hu)
IsotypeIgG
ApplicationsWB, FCM, IF, IHC-p
Conjugate/TagUnconjugated
NCBI Full Gene Nameimmunoglobulin lambda locus
Molecular Weight~22.5kDa
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)

Specifications/Features

This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant

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