Rabbit Anti-CELA3B/ELA3B Antibody MBS4380559 from MyBioSource.com

Product Specs
ItemRabbit Anti-CELA3B/ELA3B Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380559
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ApplicationsImmunohistology (Formalin-Fixed)
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Conjugate/TagUnconjugated
ReactivityHuman. Others not known
SpeciesRabbit
Molecular Weight~17kDa
TargetCELA3B/ELA3B
IsotypeIgG
CloneCELA3B/2810R
ClonalityMonoclonal
NCBI Full Gene Namechymotrypsin like elastase family member 3B
NCBI Gene AliasesELA3B, CBPP

Specifications/Features

This MAb recognizes a protein of ~30kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function

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