Rabbit Anti-P40 Antibody MBS4381362 from MyBioSource.com

Product Specs
ItemRabbit Anti-P40 Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4381362
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ClonalityPolyclonal
ReactivityHuman
Format200ug/ml of Ab Purified by Protein A Column. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ApplicationsImmunohistochemistry (IHC) Paraffin
SpeciesRabbit
Molecular Weight40kDa
Targetp40
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
NCBI Full Gene Nametumor protein p63
NCBI Gene AliasesEEC3, TP53CP, p63, LMS, SHFM4, B(p51B), TP53L, RHS, NBP, B(p51A), AIS, p51, p53CP, TP73L, p73L, KET, OFC8, p73H, p40
Conjugate/TagUnconjugated
IsotypeIgG

Specifications/Features

p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibody s ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques

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