Rabbit Anti-Ksp-Cadherin/CDH16 Antibody MBS4380769 from MyBioSource.com

Product Specs
ItemRabbit Anti-Ksp-Cadherin/CDH16 Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380769
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
NCBI Full Gene Namecadherin 16
Conjugate/TagUnconjugated
ApplicationsImmunohistochemistry-paraffin (IHC-p)
IsotypeIgG
ReactivityHu, Ms, Rt
TargetKsp-Cadherin (Kidney-Specific Cadherin)/CDH16
Molecular Weight130kDa
SpeciesRabbit
Format200ug/ml of Ab Purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ClonalityPolyclonal
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)

Specifications/Features

This antibody recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma

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