MyBioSource.com's Rabbit Anti-Histone H2A Antibody is a Rabbit monoclonal antibody. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling