Rabbit Anti-PDCD1/PD1/CD279 Antibody MBS4381153 from MyBioSource.com

Product Specs
ItemRabbit Anti-PDCD1/PD1/CD279 Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4381153
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ReactivityHuman
Format200ug/ml of Ab Purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
SpeciesRabbit
Molecular Weight55kDa
TargetPDCD1/PD1/CD279 (Programmed Cell Death 1)
Conjugate/TagUnconjugated
IsotypeIgG
ApplicationsImmunohistochemistry-paraffin (IHC-p)
NCBI Gene AliaseshPD-l, CD279, PD-1, PD1, hSLE1, SLEB2, hPD-1
NCBI Full Gene Nameprogrammed cell death 1
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
ClonalityPolyclonal

Specifications/Features

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells

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