MyBioSource.com's RNF7 Antibody - N-terminal region is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
This is a rabbit polyclonal antibody against RBX2. It was validated on Western Blot
Target Description: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported