CD3e (T-Cell Marker) Antibody MBS4381387 from MyBioSource.com

Product Specs
ItemCD3e (T-Cell Marker) Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4381387
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ClonalityMonoclonal
ReactivityHuman
Format200ug/ml of Ab Purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml
ApplicationsFlow Cytometry (FC/FACS), Immunohistochemistry (IHC) Frozen, Immunofluorescence (IF), Functional Studies
SpeciesMouse
Molecular Weight23kDa
TargetCD3e
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA at 1.0mg/ml
NCBI Full Gene NameCD3e molecule
NCBI Gene AliasesTCRE, T3E, IMD18
Conjugate/TagUnconjugated
IsotypeIgG2a kappa
CloneOKT3

Specifications/Features

Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. It is found on all mature T-lymphocytes, NK, T-cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. It is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. This MAb has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection

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