The BACE1 Mouse mAb Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human, Mouse, and Rat antigen. The BACE1 Mouse mAb Antibody has been shown to work in the following applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, and Western Blot.
Description
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene